DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sele and hig

DIOPT Version :9

Sequence 1:	XP_008767830.1	Gene:	Sele / 25544	RGDID:	3654	Length:	619	Species:	Rattus norvegicus
Sequence 2:	NP_724773.1	Gene:	hig / 35949	FlyBaseID:	FBgn0010114	Length:	958	Species:	Drosophila melanogaster

Alignment Length:	316	Identity:	89/316 - (28%)
Similarity:	125/316 - (39%)	Gaps:	57/316 - (18%)

- Green bases have known domain annotations that are detailed below.

  Rat   191 EYPDHGSLNCTHPFGLFSYNSSCSFSCERGYVPSSMETTVRCTSSGEWSAP-APACHVVECKALT 254
            |..|.|:..||.|.||                .:|:...|..::..:.:.| ||....:|...|.
  Fly   686 ENNDSGTFTCTSPRGL----------------TNSIAVVVATSTCPQLTEPLAPLKLRLEGNKLG 734

  Rat   255 QPAHGVRKCSSNPGSYPWNTTCTFDCEEGYRRVGAQNLQCTSSGVWDNEKPSCKAVTCDAIPR-- 317
            |.||                   ::|.||:|..||.|..|.:||.|.:..|:|.|:.|   ||
  Fly   735 QRAH-------------------YECPEGFRLDGAWNATCLASGNWSSPTPTCHAIQC---PRLE 777

  Rat   318 ---PQNGSVSCSNSTAGALAFKSSCNFTCEHSFTLQGPAQVECSAQGQWTPQIPVCKASQCEALS 379
               |....:..:.|..|...||      |:..|.|.||||::|...|.|:..:|.||..||....
  Fly   778 LDDPHLSLIELNTSAWGRAVFK------CQWGFKLTGPAQLDCEPSGVWSGPVPRCKVIQCVMPV 836

  Rat   380 APQRGHMKCLPSASAPFQSGSSCKFSCDEGFELKGSRRLQCGPRGEWDSEKPTCAAVRCDAVPWP 444
            ||..|.:.....:......|:...|||::|..|.|...:.|...|:|....|.|.: :|.....|
  Fly   837 APLNGRIGGTSLSQRRLTVGALVTFSCNDGHSLVGESSIICTENGQWSHSPPFCKS-QCPYPGDP 900

  Rat   445 QNGFAACAHANTGAFTYKSSCAFQCNEGF--KLHGSAQL-ECTSQGTWTQEVPSCQ 497
            .||..|....|..|..|.|   .||..||  ...|..:. :|...|.|:..:|.|:
  Fly   901 PNGLIAPLKFNYDAGDYLS---VQCRPGFVQSYEGPPERPKCQPDGRWSGPMPKCK 953

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sele	XP_008767830.1	CLECT_selectins_like	29..147	CDD:153062
		EGF_CA	<155..181	CDD:238011
		CCP	193..245	CDD:153056	12/52 (23%)
		CCP	250..308	CDD:153056	16/57 (28%)
		PHA02927	310..555	CDD:222943	57/196 (29%)
		CCP	312..371	CDD:153056	19/63 (30%)
		CCP	375..433	CDD:153056	15/57 (26%)
		CCP	438..497	CDD:153056	18/61 (30%)
		CCP	501..556	CDD:153056
hig	NP_724773.1	PHA02927	705..952	CDD:222943	79/278 (28%)
		CCP	714..768	CDD:153056	20/72 (28%)
		CCP	<795..828	CDD:153056	13/38 (34%)
		CCP	832..891	CDD:153056	15/58 (26%)
		Sushi	894..952	CDD:278512	18/60 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I11952
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19325
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.100