DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab4a and Rab14

DIOPT Version :9

Sequence 1:	NP_037151.2	Gene:	Rab4a / 25532	RGDID:	3529	Length:	218	Species:	Rattus norvegicus
Sequence 2:	NP_788056.1	Gene:	Rab14 / 34840	FlyBaseID:	FBgn0015791	Length:	239	Species:	Drosophila melanogaster

Alignment Length:	220	Identity:	126/220 - (57%)
Similarity:	155/220 - (70%)	Gaps:	11/220 - (5%)

- Green bases have known domain annotations that are detailed below.

  Rat     4 TAMSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWD 68
            ||....|:::||:::||:.|.|||||||||.||||..:..||||||||::||.|..|.:||||||
  Fly    26 TAAPYNYNYIFKYIIIGDMGVGKSCLLHQFTEKKFMANCPHTIGVEFGTRIIEVDDKKIKLQIWD 90

  Rat    69 TAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDLDAD 133
            ||||||||:|||||||||||||:|||||.|.|||.|::||||.|.|.:.:.||.|.|||.||::.
  Fly    91 TAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDTRNLTNPSTVIFLIGNKSDLEST 155

  Rat   134 REVTFLEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIESGELDPERMGSGIQYGDAA 198
            ||||:.||..||.||.|||||.||:||:||||||::.||||...|:.|.||.....||:|:..:
  Fly   156 REVTYEEAKEFADENGLMFLEASAMTGQNVEEAFLETARKIYQNIQEGRLDLNASESGVQHRPS- 219

  Rat   199 LRQLRSPRRTQAPS-----AQECGC 218
                 .|.||...|     ..:|.|
  Fly   220 -----QPSRTSLSSEATGAKDQCSC 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab4a	NP_037151.2	Rab4	14..174	CDD:206696	108/159 (68%)
Rab4a	NP_037151.2	Effector region. /evidence=ECO:0000250	42..50		5/7 (71%)
Rab14	NP_788056.1	Rab14	34..199	CDD:133322	110/164 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1146851at2759
OrthoFinder	1	1.000	-	-		FOG0001311
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X808
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920