Protein Alignment Man2a1 and LManII

DIOPT Version :9

• Sequence 1: NP_037111.2
• Gene: Man2a1 / 25478
• RGDID: 3038
• Length: 1148
• Species: Rattus norvegicus
• Sequence 2: NP_609408.1
• Gene: LManII / 34437
• FlyBaseID: FBgn0027611
• Length: 1080
• Species: Drosophila melanogaster
• Alignment Length: 1131
• Identity: 287/1131 - (25%)
• Similarity: 469/1131 - (41%)
• Gaps: 258/1131 - (22%)

  Rat   165 LQVFVVPHSHNDPGWLKTFNDYF--------RDKTQYIFNNMVLKLKEDSSRKFIWSEISYLAKW 221
            |.|.:|.|:|:|.|||||.:.|:        :...|||.:::|..|..|..::||:.|.::..||
  Fly    47 LNVHLVAHTHDDVGWLKTVDQYYYGSETKIQKAGVQYIIDSVVEALLRDPEKRFIYVESAFFFKW 111

  Rat   222 WDIIDNPK-KEAVKSLLQNGQLEIVTGGWVMADEATTHYFALIDQLIEGHQWLEKNLGV--KPRS 283
            |. ...|| :||||.|::.|:||.:.|.|.|.|||||||.::|||...|.:.|....|.  :||.
  Fly   112 WK-EQKPKVQEAVKMLVEQGRLEFIGGAWSMNDEATTHYQSVIDQFSWGLRLLNDTFGECGRPRV 175

  Rat   284 GWAIDPFGHSPTMTYLLKRAGFSHMLIQRVHYSVKKHFSLQKTLEFFWRQNWDLGSTTDILCHMM 348
            ||.|||||||..|..:..:.||..|...|:.|..|....:.|..|..|..:.:||...|:....:
  Fly   176 GWQIDPFGHSREMASMFAQMGFDGMFFGRLDYQDKDERLMTKNAEMIWHGSANLGEEADLFSGAL 240

  Rat   349 PFYSYDIPH------TCGPDPKICCQFDFKRLPGGRYGCPWGVPPEAISPGNVQSRAQMLLDQYR 407
             :.:|..|.      .|...|.|    |.|..|                ..||:.|....||..:
  Fly   241 -YNNYQAPDGFCFDILCNDAPII----DGKHSP----------------DNNVKERIDTFLDFAK 284

  Rat   408 KKSKLFRTKVLLAPLGDDFRFSEYTEWDLQYRNYEQLFSYMNSQP--HLKVKIQFGTLSDYFDAL 470
            .:|:.:||..::..:|.||   .|....:.|:|.::|..|.|.:.  ...:.:.:.|.|.|..:|
  Fly   285 TQSQYYRTNNIIVTMGGDF---TYQAAQVYYKNLDKLIRYGNERQANGSNINLLYSTPSCYLKSL 346

  Rat   471 EKSVAAEKKGGQSVFPALSGDFFTYADRDDHYWSGYFTSRPFYKRMDRIMESRLRTAEILYHLAL 535
            ..:        ...:|..|.|||.||.....||:|||||||..||.:|.....|:..:.|..||.
  Fly   347 HDA--------GITWPTKSDDFFPYASDPHAYWTGYFTSRPTLKRFERDGNHFLQVCKQLSALAP 403

  Rat   536 KQAQKYKINKFLSSPHYTTLTEARRNLGLFQHHDAITGTAKDWVVVDYGTRLFQSLNSLEKIIGD 600
            |:.:::       .||   ||..|..||:.|||||||||.|:.|.:||..|:..:..:......:
  Fly   404 KKPEEF-------DPH---LTFMRETLGIMQHHDAITGTEKEKVALDYAKRMSVAFRACGATTRN 458

  Rat   601 SAFLLILKDKKLYQSDPSKAFLEMDTKQSSQDSLPKKNIIQLSAQEPRY-LVVYNPFEQERHSVV 664
            :...|.::.|...:...:|...|..|     .:|.......:|....|: |.:|||.....:..|
  Fly   459 ALNQLTVQSKDNVKDTSAKYVFEFKT-----CALLNITSCPVSEANDRFALTLYNPLAHTVNEYV 518

  Rat   665 SVRVNSATVKVLSDLGKAVE---VQVSAVWKDMR-TTSQAAYEVAFLA-HLPPLGLKVYKILESQ 724
            .:.|..:..:::.:.|..:|   |.:..|..|:: ..|.|.||:.||| ::|.||.:.|.:.:..
  Fly   519 RIPVPYSNYRIIDNKGVTLESQAVPIPQVLIDIKHRNSTAKYEIVFLATNIPALGYRTYYVEKLD 583

  Rat   725 SSSSHLADYFLYNNDGQAESGIFHMKNMVDSGDAIT-IENSFLTLGFDRSGLMEKVRRKEDNKQQ 788
            |:            :|...|     |.:.....::| |.||.:.||||.:|.:.:|  ..|...:
  Fly   584 ST------------EGNTRS-----KALPKRTSSVTVIGNSHIQLGFDTNGFLSEV--TADGLTR 629

  Rat   789 ELKVQFLWY--GTTNKRD----KSGAYLFLPDGQGQPYVSLRTPFVRVTRGRIYSDV-TCFLEHV 846
            .:..:||:|  ...|..:    .||||:|.|: :.:.:.:.....:.|.:|.:..:| ..|.:.:
  Fly   630 LVSQEFLFYEGAVGNNAEFLNRSSGAYIFRPN-ENKIHFATDQVEIEVYKGDLVHEVHQKFNDWI 693

  Rat   847 THKVRLYH------IQGIEGQSMEVSNIVDIRSVHNREIVMRISSKINNQNRYYTDLNGYQIQPR 905
            :..||:|:      .:.:.|.       :.|.....:|::.|.:|.|.:...:.||.||.::..|
  Fly   694 SQVVRVYNKDSYAEFEWLVGP-------IPIDDGIGKEVITRFNSDIASDGIFRTDSNGREMIKR 751

  Rat   906 RT------MAKL--PLQANVYPMSTMAYIQDAAHRLTLLSAQSLGASSMASGQIEVFMDRRLMQD 962
            :.      ..|:  .:..|.||::|...::|...|:.:|:.::.|.||:..|.:|:.:.|||::|
  Fly   752 KINHRDTWSVKINEAVAGNYYPITTKIDVEDDTARMAILTDRAQGGSSLKDGSLELMVHRRLLKD 816

  Rat   963 DNRGLGQGVH-----DNKITANLFRILLEK---RNGMNM-------EEDKKSPVSYPSLLSHM-- 1010
            |..|:|:.::     |..|......:...|   |.|:::       :.:|..|..  ...|:|
  Fly   817 DAFGVGEALNETEYGDGLIARGKHHLFFGKSTDREGVSLKGIERLTQLEKLLPTW--KFFSNMED 879

  Rat  1011 ------TSAFLNHPFLPMVLSG---QLPSPAIEL------------------------------- 1035
                  .:||.|      :.||   .||.|...|
  Fly   880 YSADEWQTAFTN------IFSGISLVLPKPVHLLTLEPWHENQLLVRFEHIMENGEDASYSQPVQ 938

  Rat  1036 -------------------------LSEFRLLQ---------------SSLPCD-IHLVNLRTIQ 1059
                                     |.|.|.||               .|.|.: :||::..  :
  Fly   939 FNVKNVLSAFDVEGIRETTLDGNAWLDESRRLQFAPDPEEAAFNTYATFSQPAESVHLLSAE--K 1001

  Rat  1060 SKVGKGYSDEAALILH--------RKVFDCQLSSRAMGLPCSTTQGKMSIPKLFNNFAVESFIPS 1116
            ..:|..|:|||.....        |:..:.:...:..|....:|:|.      :|:|..:|
  Fly  1002 PMLGVKYADEALPAGQLGAESNRIRRETETRQEKKDEGRSSKSTEGP------YNSFKSDS---- 1056

  Rat  1117 SLSLMHSPPDAQNTSEVSLSPMEIST 1142
                      :.....:.||||||.|
  Fly  1057 ----------SNQEYIIELSPMEIRT 1072

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Man2a1	NP_037111.2	PLN02701	127..1148	CDD:178304	287/1131 (25%)
		GH38N_Man2A1	164..507	CDD:212131	113/360 (31%)
		Alpha-mann_mid	502..587	CDD:214875	37/84 (44%)
		Glyco_hydro_38C	733..1142	CDD:285047	107/536 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1121..1148		7/22 (32%)
LManII	NP_609408.1	GH38N_AMII_LAM_like	47..323	CDD:212121	98/300 (33%)
		Alpha-mann_mid	370..445	CDD:214875	37/84 (44%)
		Glyco_hydro_38C	502..957	CDD:285047	103/489 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810