Protein Alignment Man2a1 and LManIII

DIOPT Version :9

• Sequence 1: NP_037111.2
• Gene: Man2a1 / 25478
• RGDID: 3038
• Length: 1148
• Species: Rattus norvegicus
• Sequence 2: NP_001285762.1
• Gene: LManIII / 34203
• FlyBaseID: FBgn0032066
• Length: 1003
• Species: Drosophila melanogaster
• Alignment Length: 1098
• Identity: 270/1098 - (24%)
• Similarity: 455/1098 - (41%)
• Gaps: 228/1098 - (20%)

  Rat   155 YEA-DEWDREPLQVFVVPHSHNDPGWLKTFNDYFRDK--------TQYIFNNMVLKLKEDSSRKF 210
            ||: .|.....:.:.:|||||:|.|||||.:.|:...        .||||:.:|.:|.:||.|:|
  Fly    26 YESCPETKSNMINIHLVPHSHDDLGWLKTVDQYYYGNKHNIQHAGVQYIFDTVVAELSKDSRRRF 90

  Rat   211 IWSEISYLAKWWDIIDNPKKEAVKSLLQNGQLEIVTGGWVMADEATTHYFALIDQLIEGHQWLEK 275
            |..|..:.||||:.....||:.||:|:..|:||...|.|.|.|||..:|.::|||...|.::|..
  Fly    91 IQVETGFFAKWWEDQSETKKKLVKTLVNEGRLEFTGGAWSMNDEAAVNYQSVIDQFAVGLKFLND 155

  Rat   276 NLGV--KPRSGWAIDPFGHSPTMTYLLKRAGFSHMLIQRVHYSVKKHFSLQKTLEFFWRQNWDLG 338
            |.||  :||.||.||.||||.....:..:..|......|:..:.|........||..    ||..
  Fly   156 NFGVCGRPRVGWQIDAFGHSREQASMFAQMAFDGQFFARMDQNDKNKRVDNLGLEMV----WDAS 216

  Rat   339 STTDILCHMMPFYS---YDIPHTCGPDPKIC----CQFDFKRLPGGRYGCPWGVPPEAISPGNVQ 396
            .|.:    .|.|::   |:  |...| |..|    || |...:.|..|            ..||:
  Fly   217 ETLE----EMDFFTGMLYN--HYSAP-PGFCFDSLCQ-DDPIIDGKSY------------DNNVK 261

  Rat   397 SRAQMLLDQYRKKSKLFRTKVLLAPLGDDFRFSEYTEWDLQYRNYEQLFSYMNSQ--PHLKVKIQ 459
            ||....|:.....:..:|:..::.|:||||   :|....:.|:|.::|..|:|.:  ...|..|.
  Fly   262 SRVDDFLNYASNLAGYYRSNHIMVPMGDDF---QYENAYMNYKNMDKLIKYVNERQASGSKYNIF 323

  Rat   460 FGTLSDYFDALEKSVAAEKKGGQSVFPALSGDFFTYADRDDHYWSGYFTSRPFYKRMDRIMESRL 524
            :.|...|.::|.||:.:        ||..:.||..::.....:|:|:|||||..||.:|.....|
  Fly   324 YSTAGCYLNSLHKSLQS--------FPNKTQDFLPHSHEAKSFWTGFFTSRPTQKRFERDGNHIL 380

  Rat   525 RTAEILYHLA-LKQAQKYKINKFLSSPHYTTLTEARRNLGLFQHHDAITGTAKDWVVVDYGTRLF 588
            :.|:.|..|| |...:::|...:|           |:.:.:.|||||||||.|..|..||...|:
  Fly   381 QVAKQLSVLADLSGEEQHKDLDYL-----------RQIMAVMQHHDAITGTEKQEVSNDYDRLLY 434

  Rat   589 QSLNSLEKIIGDSAFLLILKDKKLYQSDPSKAFLEMD------TKQSSQDSLPKKNIIQLSAQEP 647
            .::........|:..:|..:....:||     .|:::      ||:::.|.:
  Fly   435 DAILGGANTARDALRVLTNQPNGEFQS-----CLKLNISECAFTKENADDFM------------- 481

  Rat   648 RYLVVYNPFEQERHSVVSVRVNSATVKVLSDLGKAVEVQVSAV-WKDMR---TTSQAAYEVAFLA 708
              :.:|||........|.|.|...:.:|..:.|..|..::..| |:.:.   ..:...:|:.|
  Fly   482 --VTLYNPLAHTSTQYVRVPVKEDSYQVTDEKGGLVASELVPVPWEVLSLEFRNNDTQHELVF-- 542

  Rat   709 HLPPLGLKVYKILESQSSSSHLADYFLYNND-----------------GQAESGIFHMKNM---- 752
                           ::|.:.:|.||:...|                 .:.||.:...|..
  Fly   543 ---------------KASVNKIATYFIKKIDKTTEVDITVNTQTEQSVNEEESNVKVPKRFKKVH 592

  Rat   753 --------VDSGDAITIENSFLTLGFD-RSGLMEKVRRKEDNKQQELKVQFLWYGTTNKRDKSGA 808
                    :|..:.| ::||.:.|..| .:|.::.|  :.:...:::...|..|.|.    :|..
  Fly   593 SLKTDLETLDDQETI-VQNSLIKLVIDNNTGRLKTV--EMNGVSEDIDQTFGMYKTA----RSCH 650

  Rat   809 YLFLPDGQGQPYVSLRTPFVRVTRGRIYSDVTCFL-EHVTHKVRLYHIQGIEGQSME-VSNIVDI 871
            |:|..|...: .|.....|. |..|....:|...: |.::..:|:|  :|:.....| :...|.|
  Fly   651 YIFRQDADLE-LVEDAFDFT-VYDGESVKEVHQHVNEWISQVIRIY--EGVNRVEFEWLVGPVPI 711

  Rat   872 RSVHNREIVMRISSKINNQNRYYTDLNGYQIQPRR---------TMAKLPLQANVYPMSTMAYIQ 927
            .....:|||....|.|::...:|||.||.::..|.         .:::.|:..|.||:::...:|
  Fly   712 DDELGKEIVTIFKSGISSGGVFYTDSNGREMMRREKDKREDFSPDLSEQPVSGNYYPVTSRMALQ 776

  Rat   928 DAAHRLTLLSAQSLGASSMASGQIEVFMDRRLMQDDNRGLGQGVHDNKI------TANLFRILLE 986
            |::.|:.||:.:|.|.:|:..|::|:.:.||.:..|..|..:.:::.:.      ...||..|..
  Fly   777 DSSKRMVLLNDRSQGGASLEDGRLEMMLHRRHIFADGSGAAEAINEQQFGKGLIARGKLFLYLNA 841

  Rat   987 KRNGMNMEEDKKSPVSYPSLLSHMTSAFLNHPFLPMV-LSGQLPSPAIELLSEFRLLQSSLPCDI 1050
            ..:|....|             .:....::.||.... .|..:.|...:.||:|    :.||..:
  Fly   842 IEDGATASE-------------RVAEKEIHLPFWKFFSKSNNIQSDVTKTLSDF----NDLPQSV 889

  Rat  1051 HLVNLRTIQSKVGKGYS-DEAALILH---------------RKVFDCQLSSRAMGLPCSTTQGKM 1099
            ||:.|        :.|| ||..|.|.               |::||   ....:.:..:|..|.:
  Fly   890 HLLTL--------EPYSKDEILLRLENFLDQTEGNVVSFSIRQIFD---DLGGLEIRETTLDGNL 943

  Rat  1100 SIPKL------FNNFAVESFIPSSLSLMHSPPDAQNTSE-----VSLSPMEISTSRIR 1146
            .:..:      .:.......:|...:.:|.|..|..|.:     |:|.||:|.|..|:
  Fly   944 PLSDMKRLKFHHDGSGPSHSVPEYFTSLHKPLAADKTQDASEFSVTLKPMQIRTFIIK 1001

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Man2a1	NP_037111.2	PLN02701	127..1148	CDD:178304	270/1098 (25%)
		GH38N_Man2A1	164..507	CDD:212131	111/361 (31%)
		Alpha-mann_mid	502..587	CDD:214875	32/85 (38%)
		Glyco_hydro_38C	733..1142	CDD:285047	100/483 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1121..1148		11/31 (35%)
LManIII	NP_001285762.1	GH38N_AMII_LAM_like	37..311	CDD:212121	97/300 (32%)
		Alpha-mann_mid	358..433	CDD:286360	32/85 (38%)
		Glyco_hydro_38C	603..998	CDD:285047	93/433 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810