DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPAPB1A11.03 and CG18003

DIOPT Version :9

Sequence 1:	NP_593999.1	Gene:	SPAPB1A11.03 / 2543401	PomBaseID:	SPAPB1A11.03	Length:	407	Species:	Schizosaccharomyces pombe
Sequence 2:	NP_001027401.1	Gene:	CG18003 / 3771779	FlyBaseID:	FBgn0061356	Length:	366	Species:	Drosophila melanogaster

Alignment Length:	356	Identity:	130/356 - (36%)
Similarity:	198/356 - (55%)	Gaps:	24/356 - (6%)

- Green bases have known domain annotations that are detailed below.

pombe    39 WEQLAVERMTKDAAGYVYGCAGKRETYDKNMESFKKWSIIPNRLIKSGFPDLSTTVFGQKYPFPI 103
            :|:.||.::.|:|..|....||::.|...|.|:|::..:.|..|......|:||.:||::..:|:
  Fly     9 FEKKAVGQLEKNALDYYRSGAGEQFTLGLNREAFRRLRLRPRCLRDVSRLDISTKIFGEQMQWPL 73

pombe   104 ALAPVGVQKIFNPEGESGSCAAATREHIPYIISTASATSFEDIEKASGPGERWYQLYWPSNDHQD 168
            .:||..:||:.:|:||.|:..||.:....:|:||.|.||.||:...:....:|:|||    .::|
  Fly    74 GIAPTAMQKMAHPDGEVGNARAAGKAGSIFILSTLSTTSLEDLAAGAPDTIKWFQLY----IYKD 134

pombe   169 ITIS--LLNRAKKTGCRVLIVTLDTFILGWRPSDMDNGYDPFLNPDSIGVEHGFSDPVFRKQFKE 231
            .||:  |:.||:|...:.|::|:|..|.|.|.:|:.|.   |..|..:.:.:          |:.
  Fly   135 RTITEKLVRRAEKANFKALVLTIDAPIFGHRRADVRNN---FSLPSHLSLAN----------FQG 186

pombe   232 KHGVEVEENMLEAA--KEFAGIVF-PGISHDWEDLKFLRKHWDGPIVLKGIMNVPDAKKAVEYGM 293
            .....|....:.|:  .|:....| |.|:  |:|:.:|:.....|||:||::...||..|.|:|.
  Fly   187 VKATGVGNAAMGASGINEYVSSQFDPTIT--WKDIAWLKGITHLPIVVKGVLTAEDAVLAQEFGC 249

pombe   294 QGIVVSNHGGRQQDGGVASLTMLPKIVDAVGDKLDVLFDSGVRSGADIAKALALGAKMVLIGRPY 358
            .|::|||||.||.|...||:..||:||.||||.|.|:.|.|:..|.||.||||||||.|.:|||.
  Fly   250 AGLIVSNHGARQIDTVPASIEALPEIVKAVGDNLVVMLDGGIMQGNDIFKALALGAKTVFVGRPA 314

pombe   359 VYGLALEGSSGVSHVIRCLLGDLELTLHLSG 389
            |:|||..|..||..::..|..|.|.|:.|.|
  Fly   315 VWGLAYNGQKGVEEMLSVLRKDFETTMALIG 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPAPB1A11.03	NP_593999.1	LMO_FMN	16..403	CDD:239448	130/356 (37%)
SPAPB1A11.03	NP_593999.1	FMN_dh	45..405	CDD:279418	127/350 (36%)
CG18003	NP_001027401.1	alpha_hydroxyacid_oxid_FMN	7..353	CDD:239203	130/356 (37%)
CG18003	NP_001027401.1	FMN_dh	17..359	CDD:279418	127/348 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	200	1.000	Domainoid score	I659
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	205	1.000	Inparanoid score	I976
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001123
OrthoInspector	1	1.000	-	-		oto100585
orthoMCL	1	0.900	-	-		OOG6_100930
Panther	1	1.100	-	-	O	PTHR10578
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1926
SonicParanoid	1	1.000	-	-		X693
TreeFam	0	0.000	Not matched by this tool.
	9	8.990