DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sid1 and par-1

DIOPT Version :9

Sequence 1:	NP_593564.1	Gene:	sid1 / 2542746	PomBaseID:	SPAC9G1.09	Length:	471	Species:	Schizosaccharomyces pombe
Sequence 2:	NP_995894.2	Gene:	par-1 / 2768852	FlyBaseID:	FBgn0260934	Length:	1170	Species:	Drosophila melanogaster

Alignment Length:	357	Identity:	93/357 - (26%)
Similarity:	161/357 - (45%)	Gaps:	78/357 - (21%)

- Green bases have known domain annotations that are detailed below.

pombe     9 YTLLRKLGSGSFGVVWKARENVSGDIIAIKQID---LETGIDDITDIEQEVFMLSNCNSSNVIQY 70
            |.|::.:|.|:|..|..|:...:|..:|||.||   |..|  .:..:.:||.::...:..|:::.
  Fly   253 YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPG--SLQKLFREVRIMKMLDHPNIVKL 315

pombe    71 YGCFVDGYTLWILMEHMDGGSVSGLLKM-GRLNEQVISIILREVLYGLNYLHGQNKIHRDIKAAN 134
            :.......||:::||:..||.|...|.: ||:.|:...:..|:::..:.|.|.:..||||:||.|
  Fly   316 FQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAEN 380

pombe   135 ILLSSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVIQQTSY-GLAADIWSLGITAIEM 198
            :||.|.. |:|:||||.:.:.: ..|:..||.|:|.:.|||:.|...| |...|:||||:....:
  Fly   381 LLLDSEL-NIKIADFGFSNEFT-PGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTL 443

pombe   199 ANGIPP--RATMHPM--RVI---FEIPQSEPPKLDDHFSPTFRDFVSCCLDLNPNMRWSAKELLQ 256
            .:|..|  .:|:..:  ||:   :.||        .:.|....:.:...|.|||..|.|.:.::.
  Fly   444 VSGSLPFDGSTLRELRERVLRGKYRIP--------FYMSTDCENLLRKFLVLNPAKRASLETIMG 500

pombe   257 HPFIKSAGTVKDIIPLLVQKENKLFDDSDQSVLEETINNTLKPFEEPIAEGNADIEDWTFETVKK 321
            ..::                 |..|::.:           |||:.||    .||:.|
  Fly   501 DKWM-----------------NMGFEEDE-----------LKPYIEP----KADLAD-------- 525

pombe   322 SDSTVLGNTSIPKN---SIISSQNKEELPSSI 350
                       ||.   .:....|:.|:.:|:
  Fly   526 -----------PKRIEALVAMGYNRSEIEASL 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sid1	NP_593564.1	STKc_MST3_like	7..279	CDD:270786	78/281 (28%)
sid1	NP_593564.1	S_TKc	9..260	CDD:214567	78/262 (30%)
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	78/262 (30%)
		S_TKc	253..504	CDD:214567	78/262 (30%)
		UBA_MARK_Par1	525..563	CDD:270522	6/41 (15%)
		MARK1-3_C	839..936	CDD:213381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910