DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment apm4 and stnB

DIOPT Version :9

Sequence 1:	NP_592921.1	Gene:	apm4 / 2541527	PomBaseID:	SPAC31A2.09c	Length:	446	Species:	Schizosaccharomyces pombe
Sequence 2:	NP_001036318.2	Gene:	stnB / 4379834	FlyBaseID:	FBgn0016975	Length:	1262	Species:	Drosophila melanogaster

Alignment Length:	450	Identity:	94/450 - (20%)
Similarity:	146/450 - (32%)	Gaps:	146/450 - (32%)

- Green bases have known domain annotations that are detailed below.

pombe   102 DNVSFIFELLDEMIDYGIIQTTEPDALARSVSIT----------------AVKKKGN---ALSLK 147
            |....||.:..:.|.|.......|..:.::..||                .||:.|:   .|.|.
  Fly   795 DQFGKIFTMKLQYIFYKERPGVRPGQVTKAERITNKLTKFAQYAIAGDYEGVKEFGSDLKKLGLP 859

pombe   148 RSH---SSQLAHTTS-------------SEIPGSVP-WRRAGIKYRKNSIYIDIVERMNLLISST 195
            ..|   ||||....|             .|....:| .|...:.|:...:.:..|:.:.:.....
  Fly   860 VEHAPQSSQLFKIGSMNYEDMKQFSVCIEEALFKIPALRERALTYKMEEVQVTAVDEITVEQDFE 924

pombe   196 GNVLRSDVSGVVKMR----AMLSGMPECQFGLNDKLDFKLKQSESKSKSNNSRNPSSVNG----- 251
            |.:|:.    :.::|    |.|:|||..:.|:||..                |....|.|
  Fly   925 GKILKQ----IARVRLFFLAFLTGMPTIELGVNDMW----------------RQGKEVVGRHDII 969

pombe   252 -----GFVILEDCQFHQCVRLPEFENEHRITFIPPDGE-VELMSYRSHENINIPFRIVPIVEQLS 310
                 .::.||..:||..|...|:|....|.|.|||.. :||:.:|.....|   |.:|:  ||.
  Fly   970 PVATEEWIRLEAVEFHSVVNQKEYERTRTIKFQPPDANYIELLRFRVRPPKN---RELPL--QLK 1029

pombe   311 KQKII--YRISIRADY------PHKLS----SSLNFRIPVP------------------------ 339
            ....:  .::.:|||.      ..||.    ..::.|.|:|
  Fly  1030 ATWCVSGNKVELRADILVPGFTSRKLGQIPCEDVSVRFPIPECWIYLFRVEKHFRYGSVKSAHRR 1094

pombe   340 TNVVKANPR--------------VNRGKAGYEPSENIINWKIPRFLGETELIFYAEVELSNTTNQ 390
            |..:|...|              |..|:|.||.....|.|:.||...|.:..:        ||:|
  Fly  1095 TGKIKGIERILGAVDTLQESLIEVTSGQAKYEHHHRAIVWRCPRLPKEGQGAY--------TTHQ 1151

pombe   391 QIWAKPPISLD--------FNILMFTSSGLHVQYLRVS----EPSNSKYKSIKWVRYSTR 438
            .:......|.|        :..:.||.....|.:..|.    :.|:......|:|||..|
  Fly  1152 LVCRMALTSYDQIPSELAPYAFVEFTMPATQVSHTTVRSVSVQDSDGDEPPEKYVRYLAR 1211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
apm4	NP_592921.1	Clat_adaptor_s	1..134	CDD:261170	6/31 (19%)
apm4	NP_592921.1	AP-2_Mu2_Cterm	175..445	CDD:271159	71/340 (21%)
stnB	NP_001036318.2	Trypan_PARP	377..496	CDD:114603
stnB	NP_001036318.2	AP_MHD_Cterm	897..1219	CDD:299401	72/347 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10529
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010