Protein Alignment SPBC887.12 and CG33298

DIOPT Version :9

• Sequence 1: NP_596486.1
• Gene: SPBC887.12 / 2541239
• PomBaseID: SPBC887.12
• Length: 1258
• Species: Schizosaccharomyces pombe
• Sequence 2: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Alignment Length: 1380
• Identity: 429/1380 - (31%)
• Similarity: 666/1380 - (48%)
• Gaps: 291/1380 - (21%)

pombe    46 IFGSESQYISSSGQNSTNPFLADTRIENSPLGSESKANQ-LNKQGTNVN------HIEIPLRDFN 103
            |.|:..:.|.|:.:.....| :..:|.:||.||.:.|.: .::.|:..:      |.|.|.|:.:
  Fly   112 IVGANGRPIKSAMKGHQRAF-SQGQITDSPPGSAAPAGRGHSRVGSKTDFILPPGHKEEPAREPS 175

pombe   104 DPTQPESFLPPPKNTFTSRIKKIKNLFKKEK-----------------------KQVKPEDLGPR 145
            .||.........:.  .||.:.|..|.:.|.                       :.|.|....|.
  Fly   176 APTSATGGRGHSRQ--ASRSESIYTLRRTEAPPWWKRLTLCNYNTGDKFEERSYRTVVPNHTVPP 238

pombe   146 QIILNDYSANHFLHNAVSTCKYSAFTFLPKFLKEQFSKYANLFFLFTAVVQQIPGITPVNRYTTI 210
            :....|:....|:.|.:.|.||:..:|:||.|.|||.:.|||:|:|..::..:|.|:...:...:
  Fly   239 KTPKRDHPNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAM 303

pombe   211 GPMLIVLSVSGIKEIMEDIKRKKQDQELNESPCYVLQG--TGFVEKQWKDVVVGDIVKIVSETFF 273
            .|:|.||.|:.:|::.||.:|:..|:.:|.:.|.|..|  ..:.:.:|:::.|||||.:.:....
  Fly   304 IPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETV 368

pombe   274 PADLVLLSSSEPEGLCYIETANLDGETNLK---IKQALPETAGLLKPVELGQLSGEVKSEQPNNN 335
            |||::||.:|:|:|:|||:|.:||||||||   :.:...|...:..|   .:....|:::.|...
  Fly   369 PADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVP---SKFVSRVEADAPTTK 430

pombe   336 LYTFDATLKLLPSDRELPLSPDQLLLRGAQLRNTPWVYGIVVFTGHESKLMKNTTETPIKRTSVE 400
            ||.|...| :.|:...:|:|.:.||||.::|:||.::.||||:.|||:|.|.|.:....||:.||
  Fly   431 LYRFHGAL-IHPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVE 494

pombe   401 KQVNSQILFLLCIFVFLCFASSLGALIHRSVYGS-ALSYV---KYTSNRAGMFFKGLLTFW---I 458
            :|:|..:::.:.|.:.||...::|..:..|.:.. .:.|:   |.|:|...|:.     ||   :
  Fly   495 QQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFPVPYLPPNKLTANMESMWI-----FWTYIV 554

pombe   459 LYSNLVPISLFVTFELVRYIQAQLISSDLDMYNEETDTPAACRTSSLVEELGQVGYIFSDKTGTL 523
            :...::|:||:||.||.:.:|...|.:::|:::.||:....||..::.|||||:.:||:||||||
  Fly   555 ILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTL 619

pombe   524 TRNQMEFRQCTIAGVAY------------------ADVIPEDRQFTSEDLDSDMYIYDFDTLKEN 570
            |.|:|.||:|.:.|..|                  ..:||.|      :|:|||     ..|.:.
  Fly   620 TENKMIFRRCVVNGSDYNHPPSELEKIYSKPGAPAPPLIPND------NLNSDM-----AQLTQG 673

pombe   571 LKHSENASLIHQFLLVLSICHTVI----PEYD--------------------------------- 598
            ...:.:|..|.:||:||:||:|||    |..|
  Fly   674 TYLTPHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASS 738

pombe   599 ----------------------------------------------------------------- 598
                                                                             
  Fly   739 TSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAE 803

pombe   599 -------ES----------TNSIK----------------------------------------- 605
                   ||          :|||.
  Fly   804 SSPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYR 868

pombe   606 -------YQASSPDEGALVKGAASIGYKFLARKPH--LVTVSIFGKDESYELLHICEFNSTRKRM 661
                   |:|.||||.|||..|.|.....|.|.|:  ||::.:.|....||:|.:..|:|:||.|
  Fly   869 TADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCM 933

pombe   662 SIVFR-CPDGKIRLYVKGADTVIMERL---ASDNP---YLQTTIHHLEDYATVGLRTLCIAMREV 719
            |||.| ....:|.||.||||:.||..|   :.::|   ..:.|...|:.||..|||.|.:|.|.:
  Fly   934 SIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTL 998

pombe   720 PEDEYQRWSTVFETAASSLVDRAQKLMDAAEEIEKDLILLGATAIEDRLQDGVPDTISTLQTAGI 784
            ...:|..|....:....||.:|.::|.|:..::|.:|.|||||.||||||||||:||::|.:|||
  Fly   999 NSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGI 1063

pombe   785 KIWVLTGDRQETAINIGMSCKLIDEDMGLVIVNEETKEATAESVMAKLSSIYRNEATTGNV---- 845
            .:||||||:.||||||..|.||..:.|.|:.:...:::|...::...|:.: .|:.||..:
  Fly  1064 SVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDM-ENDKTTSTLGYGQ 1127

pombe   846 ----ESMALVIDGVSLTYALD--FSLERRFFELASLCRAVICCRVSPLQKALIVKMVKRNTGEVL 904
                :..|||:||.:||:.||  ..|...|..|:..|.:|:|||.:|||||.:||:||.......
  Fly  1128 SLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRT 1192

pombe   905 LAIGDGANDVPMIQAAHVGVGISGMEGLQAVRSSDFSISQFCYLKKLLLVHGSWCYQRLSKLILY 969
            ||||||||||.|||.|.|||||||.||:|||.::||::.:|.||::|||.||.|||.|||::|||
  Fly  1193 LAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILY 1257

pombe   970 SFYKNIALYMTQFWYAFCNAFSGQVIFESWSISLYNVLFTVLPPVVIGIFDQFVSAGQLFQYPQL 1034
            .||||.|.....|||.....|||||:.:...:.|||::||.|||:.||::|:.|:...|.:.|.|
  Fly  1258 FFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYL 1322

pombe  1035 YQLGQRSEFFNLKRFWSWITNGFYHSLLLF---LCSIAVFYYDGPNKDGLASGHWVWGTTLYAAI 1096
            |:.|:....:....||..:.:..|.||::|   ||:.|       ..|   .|.|.:|||:.|:.
  Fly  1323 YKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYA-------ESD---VGIWEFGTTITASC 1377

pombe  1097 LATVLGKAALISNHWT---QYTVIATLGSFLLWIVFMPIY-AVAAPAIGFSKEYYGIIPHLYGNL 1157
            |...|...|:....||   ..:::.:||||.|:.:   :| :|.....|....|: :|...:.:.
  Fly  1378 LFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAI---VYDSVCMNCFGVRSSYW-VIFVCFASA 1438

pombe  1158 KFWASLLVLPTIALM 1172
            ..|..:::...:|::
  Fly  1439 VHWLVIMLSTVVAVL 1453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPBC887.12	NP_596486.1	PhoLip_ATPase_N	147..208	CDD:292826	20/60 (33%)
		ATPase-Plipid	157..1194	CDD:273734	402/1239 (32%)
		E1-E2_ATPase	213..>307	CDD:278548	39/98 (40%)
		Cation_ATPase	590..686	CDD:289987	49/265 (18%)
		HAD_like	<736..935	CDD:304363	100/208 (48%)
		PhoLip_ATPase_C	935..1186	CDD:292829	83/245 (34%)
CG33298	NP_995666.1	PhoLip_ATPase_N	249..299	CDD:292826	19/49 (39%)
		ATPase-Plipid	250..1473	CDD:273734	402/1239 (32%)
		E1-E2_ATPase	302..>394	CDD:278548	34/91 (37%)
		Cation_ATPase	<880..965	CDD:289987	37/84 (44%)
		HAD_like	<1177..1240	CDD:304363	37/62 (60%)
		PhoLip_ATPase_C	1223..1468	CDD:292829	83/245 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820