| Sequence 1: | NP_694984.5 | Gene: | BRWD3 / 254065 | HGNCID: | 17342 | Length: | 1802 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001074946.1 | Gene: | Brwd3 / 382236 | MGIID: | 3029414 | Length: | 1799 | Species: | Mus musculus |
| Alignment Length: | 1802 | Identity: | 1705/1802 - (94%) |
|---|---|---|---|
| Similarity: | 1755/1802 - (97%) | Gaps: | 3/1802 - (0%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANA 65
Human 66 HIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRP 130
Human 131 PELPVNYVKPPNVVNITSARQLTGCSRFGHIFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRI 195
Human 196 FTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVL 260
Human 261 QGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSS 325
Human 326 FSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARI 390
Human 391 WQYQQQEWKSIVLDMATKMTGNNLPSGEDKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITG 455
Human 456 QLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCK 520
Human 521 FSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMP 585
Human 586 PPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQDESILDGI 650
Human 651 IRELQREQDLRLINEGDVPHLPVNRAYSVNGALRSPNMDISSSPNIRLRRHSSQIEGVRQMHNNA 715
Human 716 PRSQMATERDLMAWSRRVVVNELNNGVSRVQEECRTAKGDIEISLYTVEKKKKPSYTTQRNDYEP 780
Human 781 SCGRSLRRTQRKRQHTYQTRSNIEHNSQASCQNSGVQEDSDSSSEEDETVGTSDASVEDPVVEWQ 845
Human 846 SESSSSDSSSEYSDWTADAGINLQPPKRQTRQTTRKICSSSDEENLKSLEERQKKPKQTRKKKGG 910
Human 911 LVSIAGEPNEEWFAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPW 975
Human 976 NKMDLREQEFVKIVGIKYEVGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFY 1040
Human 1041 NEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPI 1105
Human 1106 PEGTAFPDEVGAGVPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINHLLSLDFASPFAVPV 1170
Human 1171 DLSAYPLYCTVVAYPTDLNTIRRRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVT 1235
Human 1236 DVLLRFIGDQSCTDILDTYNKIKAEERNSTDAEEDTEIVDLDSDGPGTSSGRKVKCRGRRQSLKC 1300
Human 1301 NPDAWKKQCKELLSLIYEREDSEPFRQPADLLSYPGHQEQEGESSESVVPERQQDSSLSEDYQDV 1365
Human 1366 IDTPVDFSTVKETLEAGNYGSPLEFYKDVRQIFNNSKAYTSNKKSRIYSMMLRLSALFESHIKNI 1430
Human 1431 ISEYKSAIQSQKRRRPRYRKRLRSSSSSLSSSGAPSPKGKQKQMKLQPKNDQNTSVSHARTSSPF 1495
Human 1496 SSPVSDAAEGLSLYLLDDEPDGPFSSSSFGGYSRSGNSHDPGKAKSFRNRVLPVKQDHSLDGPLT 1560
Human 1561 NGDGREPRTGIKRKLLSASEEDENMGGEDKEKKETKEKSHLSTSESGELGSSLSSESTCGSDSDS 1625
Human 1626 ESTSRTDQDYVDGDHDYSKFIQTRPKRKLRKQHGNGKRNWKTRGTGGRGRWGRWGRWSRGGRGRG 1690
Human 1691 GRGRGSRGRGGGGTRGRGRGRGGRGASRGATRAKRARIADDEFDTMFSGRFSRLPRIKTRNQGRR 1755
Human 1756 TVLYNDDSDNDNFVSTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY 1802 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| BRWD3 | NP_694984.5 | WD 1 | 170..209 | 38/38 (100%) | |
| WD40 | <178..496 | CDD:441893 | 310/317 (98%) | ||
| WD40 repeat | 183..220 | CDD:293791 | 36/36 (100%) | ||
| WD 2 | 213..251 | 37/37 (100%) | |||
| WD40 repeat | 226..262 | CDD:293791 | 35/35 (100%) | ||
| WD 3 | 255..297 | 40/41 (98%) | |||
| WD40 repeat | 267..313 | CDD:293791 | 44/45 (98%) | ||
| WD 4 | 307..347 | 39/39 (100%) | |||
| WD40 repeat | 321..359 | CDD:293791 | 36/37 (97%) | ||
| WD 5 | 353..393 | 39/39 (100%) | |||
| WD40 repeat | 365..425 | CDD:293791 | 55/59 (93%) | ||
| WD 6 | 400..452 | 47/51 (92%) | |||
| WD40 repeat | 426..462 | CDD:293791 | 34/35 (97%) | ||
| WD 7 | 456..495 | 38/38 (100%) | |||
| WD40 repeat | 468..493 | CDD:293791 | 24/24 (100%) | ||
| WD 8 | 502..542 | 39/39 (100%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 768..910 | 126/141 (89%) | |||
| Bromo_WDR9_I_like | 1130..1242 | CDD:99958 | 108/111 (97%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1262..1292 | 21/29 (72%) | |||
| Bromodomain | 1301..1442 | CDD:445827 | 121/140 (86%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1326..1361 | 24/34 (71%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1438..1500 | 58/61 (95%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1520..1725 | 187/204 (92%) | |||
| Brwd3 | NP_001074946.1 | WD 1 | 170..209 | 38/38 (100%) | |
| WD40 | <178..496 | CDD:441893 | 310/317 (98%) | ||
| WD40 repeat | 183..220 | CDD:293791 | 36/36 (100%) | ||
| WD 2 | 213..251 | 37/37 (100%) | |||
| WD40 repeat | 226..262 | CDD:293791 | 35/35 (100%) | ||
| WD 3 | 255..297 | 40/41 (98%) | |||
| WD40 repeat | 267..313 | CDD:293791 | 44/45 (98%) | ||
| WD 4 | 307..347 | 39/39 (100%) | |||
| WD40 repeat | 321..359 | CDD:293791 | 36/37 (97%) | ||
| WD 5 | 353..393 | 39/39 (100%) | |||
| WD40 repeat | 365..410 | CDD:293791 | 44/44 (100%) | ||
| WD 6 | 400..452 | 47/51 (92%) | |||
| WD40 repeat | 426..462 | CDD:293791 | 34/35 (97%) | ||
| WD 7 | 456..495 | 38/38 (100%) | |||
| WD40 repeat | 468..493 | CDD:293791 | 24/24 (100%) | ||
| WD 8 | 502..542 | 39/39 (100%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 766..912 | 131/146 (90%) | |||
| Bromo_WDR9_I_like | 1128..1240 | CDD:99958 | 108/111 (97%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1258..1291 | 23/32 (72%) | |||
| Bromodomain | 1299..1439 | CDD:445827 | 121/140 (86%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1321..1366 | 34/45 (76%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1435..1482 | 45/46 (98%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1517..1723 | 188/205 (92%) |