Protein Alignment Camk2a and CaMKII

DIOPT Version :10

• Sequence 1: XP_038952520.1
• Gene: Camk2a / 25400
• RGDID: 2261
• Length: 489
• Species: Rattus norvegicus
• Sequence 2: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Alignment Length: 527
• Identity: 368/527 - (69%)
• Similarity: 423/527 - (80%)
• Gaps: 52/527 - (9%)

  Rat     2 ATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRL 66
            |...||||::.|.:.|||||||||:|:|||:...|.|:||||||||||:|||.|||||||||||.
  Fly     3 APAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRK 67

  Rat    67 LKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131
            |.|||||||||||.||.:|||:|||||||||||||||||:|||||||||||||||:|.||||.||
  Fly    68 LHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGV 132

  Rat   132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDL 196
            |||||||||||||||.||||||||||||||||:|:.||||||||||||||||||:|:||||.||:
  Fly   133 VHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDI 197

  Rat   197 WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRIT 261
            ||||||||||||||||||||||||||.||||||||:|||||||||||||:|||:|||:||:||||
  Fly   198 WACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRIT 262

  Rat   262 AAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKNDG 326
            ||||||||||..|..|||.:||||||||||||||||||||||||||||||||| .:|...||.:|
  Fly   263 AAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFS-SRSMITKKGEG 326

  Rat   327 VKKRKSSSSVQLMESSESTNTTIEDEDTK------------------------------------ 355
                     .|:.||::|::||:||:|.|
  Fly   327 ---------SQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQNIGN 382

  Rat   356 ------VRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLW 414
                  .|:|||||:||||||||::|||:.|||:|||.:||||||||||||||:|||:|||||:.
  Fly   383 SQCSSAARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVL 447

  Rat   415 SRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFH 479
            .:|.|.::|||||||:||:|:|:|||||:|:|||:|..|...|.|||||||||:||.|||.||||
  Fly   448 GKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHTHQSEETRVWHKRDNKWQNVHFH 512

  Rat   480 RSGAPSV 486
            ||.:..:
  Fly   513 RSASAKI 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Camk2a	XP_038952520.1	STKc_CaMKII	11..302	CDD:270988	245/290 (84%)
		CaMKII_AD	357..484	CDD:285524	90/126 (71%)
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	245/290 (84%)
		CaMKII_AD	390..517	CDD:285524	90/126 (71%)