DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZDHHC20 and CG5880

DIOPT Version :9

Sequence 1:NP_001316988.1 Gene:ZDHHC20 / 253832 HGNCID:20749 Length:365 Species:Homo sapiens
Sequence 2:NP_651539.3 Gene:CG5880 / 43268 FlyBaseID:FBgn0039489 Length:381 Species:Drosophila melanogaster


Alignment Length:371 Identity:90/371 - (24%)
Similarity:138/371 - (37%) Gaps:126/371 - (33%)


- Green bases have known domain annotations that are detailed below.


Human    28 WSYY---------------AYVVELCVFTIFGNEENGKTVVYLVAFHLFFVMFV---------WS 68
            |||.               :|..::|:..||...:|     |......|||:.|         .:
  Fly    22 WSYMKHCWHSLTFNAHMNSSYASDVCLTPIFWFVDN-----YTHCLGPFFVVGVAALTTSVVSIA 81

Human    69 YWMTIFTSPASPSKEFYLSNSEKERY-----------EKEFSQERQQEILRRAARALPIYTTSAS 122
            ||:.:         .|:.:.|:...|           ...|  .....::..|..  |....|..
  Fly    82 YWIGL---------PFWWAKSQLVTYFLLIVGNWLLLNVVF--HYVMAVITPAGH--PPEGVSLV 133

Human   123 KTIRYCEKCQLIKPDRAHHCSACDSCILKMDHHCPWVNNCVGFSNYKFFLLFLLYSLLYCLFVAA 187
            :.:..|.||...||.|.||||.|:.|||||||||||:|||||:.|:::|.|::.|:.|.|||:..
  Fly   134 EAVSMCGKCIAPKPPRTHHCSICNRCILKMDHHCPWLNNCVGYGNHRYFFLYMTYTTLGCLFLIL 198

Human   188 TVLEYFIKF--------WT------------------------NE----------------LTDT 204
            ..||...|:        ||                        ||                :.||
  Fly   199 FGLEIGHKYLWLDHGENWTEIEPLEGQPVKFNLSGHIIPVTHPNEYDEFVLPPAVHNLPTPIVDT 263

Human   205 RA-----KFHVLFLFFVSAMFFISVLSLFSYHCWLVGKNRTTIES----------FRAPTFSYGP 254
            .|     :..:.|:.|.:....:::.||..:|..|:.:..|::|:          .:.......|
  Fly   264 DAASPGRRRALWFMAFTNVAVVLALGSLSIWHAKLITRGETSVEAHINEAERKRHLQQQRIYINP 328

Human   255 DGNGFSLGCSKNWRQVFG--DEKKYW---LLPIF-SSLGDGCSFPT 294
                ::.|..|||:...|  ..:.:|   |||.: ...|.|.||.|
  Fly   329 ----YNFGTKKNWKLFLGLVRGRSFWRTVLLPSWHKPEGTGLSFHT 370

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZDHHC20NP_001316988.1 zf-DHHC 16..301 CDD:327686 90/371 (24%)
Substrate binding. /evidence=ECO:0000305|PubMed:29326245 140..143 2/2 (100%)
CG5880NP_651539.3 zf-DHHC 139..>201 CDD:279823 35/61 (57%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG55511
OrthoDB 1 1.010 - - D1491968at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.830

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