Protein Alignment G6PC1 and G6P

DIOPT Version :9

• Sequence 1: NP_000142.2
• Gene: G6PC1 / 2538
• HGNCID: 4056
• Length: 357
• Species: Homo sapiens
• Sequence 2: NP_001097063.1
• Gene: G6P / 33476
• FlyBaseID: FBgn0031463
• Length: 350
• Species: Drosophila melanogaster
• Alignment Length: 362
• Identity: 88/362 - (24%)
• Similarity: 164/362 - (45%)
• Gaps: 37/362 - (10%)

Human     1 MEEGMNVLHD-FGIQSTHYLQVNYQDSQD--------WFILVSVIADLRNAFYVLFPIWFHLQEA 56
            ||..:::|.| :....|..|.:| :.:|:        |..| ||..:....|.::.|:.....:.
  Fly     1 MESIVHILSDAYHTTLTRELFIN-EWAQERLSFGRPLWHFL-SVHLEPNKMFNIIIPLCGIFSQE 63

Human    57 VGIKLLWVAVIGDWLNLVFKWILFGQRPYWWVLDTDYYSNTSV---PLI--KQFPVTCETGPGSP 116
            :.:.|.....:...||...|||....||.|::  .:.::|..|   |.:  :...::||...|.|
  Fly    64 ILVHLFTAFTLISTLNSFEKWIYPETRPLWFL--REQFANNVVVKKPAVALESHQLSCEMTGGLP 126

Human   117 SGHAMGTAGVYYVMVTSTLSIF----QGKIKPTYRFRCLNVILWLGFWAVQLNVC--LSRIYLAA 175
            ..|:| |..|:.:::.|...:.    ...::.:: .||:..:|.:|     :.||  |||:|||.
  Fly   127 CAHSM-TFTVFVLILASFFFVHCWDRFAALRSSF-CRCIMYLLIIG-----MVVCMWLSRLYLAT 184

Human   176 HFPHQVVAGVLSGIAVAETF-SHIHSIYNASLKKYFLITFFLFSFAIGFYLLLKGLGVDLLWTLE 239
            .|.||.:.|...||....|| .::..:::...:......|||...|:..|.:...|.:|..|::.
  Fly   185 EFLHQCILGSYLGIRSLCTFEGNVKYLFSRPRRYAVSAVFFLGGLALSVYYVKLELNIDPHWSVR 249

Human   240 KAQRWCEQPEWVHIDTTPFASLLKNLGTLFGLGLALNSSMYRESCKGKLSKWLPFRLSSIVASLV 304
            :|.:||.:|.::..:..|..:|:::||.|  :||||.|.:|:...| :.|.|...|...::..:.
  Fly   250 EAFKWCPEPTYLRHEVGPIFALVRDLGNL--MGLALASPLYKLEMK-QSSFWRRCRFLGVLEFVN 311

Human   305 LLHVFDSLKPPSQVELVFYVLSFCKSAVVPLASVSVI 341
            ....|.:.|...:  .||....|.::.:..|..:..:
  Fly   312 YGLRFSTFKQSGR--FVFLTYEFLRNVIHSLVLIKYV 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
G6PC1	NP_000142.2	PAP2_glucose_6_phosphatase	42..280	CDD:239476	65/249 (26%)
G6P	NP_001097063.1	PAP2_glucose_6_phosphatase	49..290	CDD:239476	66/251 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146783
Domainoid	1	1.000	52	1.000	Domainoid score	I11461
eggNOG	1	0.900	-	-		E1_2CMVX
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	98	1.000	Inparanoid score	I5024
Isobase	1	0.950	-	0	Normalized mean entropy	S7962
OMA	1	1.010	-	-		QHG49592
OrthoDB	1	1.010	-	-		D325559at33208
OrthoFinder	1	1.000	-	-		FOG0001425
OrthoInspector	1	1.000	-	-		otm42077
orthoMCL	1	0.900	-	-		OOG6_111430
Panther	1	1.100	-	-	O	PTHR12591
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5586
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.750