| Sequence 1: | NP_445746.3 | Gene: | Adora2a / 25369 | RGDID: | 2049 | Length: | 410 | Species: | Rattus norvegicus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_651772.1 | Gene: | AdoR / 43583 | FlyBaseID: | FBgn0039747 | Length: | 774 | Species: | Drosophila melanogaster |
| Alignment Length: | 319 | Identity: | 116/319 - (36%) |
|---|---|---|---|
| Similarity: | 172/319 - (53%) | Gaps: | 39/319 - (12%) |
- Green bases have known domain annotations that are detailed below.
|
Rat 6 YITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAA 70
Rat 71 CHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLT 135
Rat 136 PMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAAR 200
Rat 201 RQLKQMESQ-------------------PLPGERTRSTL-------QKEVHAAKSLAIIVGLFAL 239
Rat 240 CWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKII 298 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Adora2a | NP_445746.3 | 7tmA_Adenosine_R_A2A | 4..294 | CDD:320196 | 116/313 (37%) |
| TM helix 1 | 6..30 | CDD:320196 | 9/23 (39%) | ||
| TM helix 2 | 39..61 | CDD:320196 | 13/21 (62%) | ||
| TM helix 3 | 75..97 | CDD:320196 | 9/21 (43%) | ||
| TM helix 4 | 120..136 | CDD:320196 | 6/15 (40%) | ||
| Agonist binding. /evidence=ECO:0000250 | 163..172 | 3/8 (38%) | |||
| TM helix 5 | 170..193 | CDD:320196 | 11/22 (50%) | ||
| TM helix 6 | 227..249 | CDD:320196 | 10/21 (48%) | ||
| Agonist binding. /evidence=ECO:0000250 | 241..248 | 3/6 (50%) | |||
| Agonist binding. /evidence=ECO:0000250 | 259..269 | 2/9 (22%) | |||
| TM helix 7 | 262..287 | CDD:320196 | 15/24 (63%) | ||
| Interaction with GAS2L2. /evidence=ECO:0000269|PubMed:23994616 | 322..410 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 344..410 | ||||
| AdoR | NP_651772.1 | 7tm_4 | 52..>220 | CDD:304433 | 73/179 (41%) |
| 7tm_1 | 58..334 | CDD:278431 | 107/288 (37%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C166344429 | |
| Domainoid | 1 | 1.000 | 174 | 1.000 | Domainoid score | I3568 |
| eggNOG | 1 | 0.900 | - | - | E33208_3BF5B | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000536 | |
| OrthoInspector | 1 | 1.000 | - | - | otm45013 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_107098 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24246 |
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X919 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 10 | 9.700 | |||||