Protein Alignment SLC25A30 and Dic3

DIOPT Version :10

• Sequence 1: XP_005266378.1
• Gene: SLC25A30 / 253512
• HGNCID: 27371
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_610344.2
• Gene: Dic3 / 35763
• FlyBaseID: FBgn0033248
• Length: 287
• Species: Drosophila melanogaster
• Alignment Length: 300
• Identity: 74/300 - (24%)
• Similarity: 127/300 - (42%)
• Gaps: 49/300 - (16%)

Human    11 YGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALYSGIAPA 75
            :||:.:..|..||.||||.|.:||.|.|.:.....||        |..|....|:...|:||:.:
  Fly    14 FGGVCAAIAVTGTHPIDLIKVQLQTQSQADRKTVGEI--------LKGIHERSGILGFYNGISAS 70

Human    76 MLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIANPTDVLKIRMQAQSNT 140
            ..||.:|.|.:...|::.|.....:.....:.:....||:.|::..    |.||:.:|:|   |.
  Fly    71 WFRQLTYTTTRFALYEAGKDYVDTQKVSSKMALATFAGIVGGIVGV----PGDVVTVRLQ---ND 128

Human   141 IQ---------GGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLM 196
            ::         ..:......||::||...|::|......||.::.......||..|:.|.::...
  Fly   129 VKLPEEKRRNYKHVFDGLFRIYKEEGVSSLFRGTVPAVSRAVLLTIGTNAAYDQVKQMLKIATGA 193

Human   197 GDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQR-------------VLRDGRCSGYTGTLDC 248
            |:.|..||.:|...|....:.:.|:||::|..||.:             ..:.|..:.|.|.:..
  Fly   194 GEGVPLHFATSTIAGCIAVVITQPLDVIKTTFMNAQPGEFSGIGGAFLSTAKQGPLAFYKGFIPA 258

Human   249 LLQLTVLESFSTTAKPQKLISVDAISEEADTRGFTYLSCD 288
            |::::          |..:|:. .:.|:|..| |.||..|
  Fly   259 LIRVS----------PNTIITF-VLYEQARMR-FGYLPPD 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A30	XP_005266378.1	Mito_carr	5..100	CDD:395101	28/88 (32%)
		Mito_carr	102..191	CDD:395101	20/97 (21%)
		Mito_carr	199..>252	CDD:395101	15/65 (23%)
Dic3	NP_610344.2	Mito_carr	15..91	CDD:395101	28/83 (34%)
		Mito_carr	93..187	CDD:395101	20/100 (20%)
		Mito_carr	200..281	CDD:395101	19/92 (21%)