Protein Alignment Npr3 and Gyc76C

DIOPT Version :9

• Sequence 1: XP_006232107.1
• Gene: Npr3 / 25339
• RGDID: 3196
• Length: 652
• Species: Rattus norvegicus
• Sequence 2: NP_001163473.1
• Gene: Gyc76C / 8674026
• FlyBaseID: FBgn0266136
• Length: 1525
• Species: Drosophila melanogaster
• Alignment Length: 591
• Identity: 117/591 - (19%)
• Similarity: 226/591 - (38%)
• Gaps: 141/591 - (23%)

  Rat   105 SRWPGRALAGNRMRSLLLFTFSACVLLARALLAGGASSGGGDTGPGNRRREREALAAQKIEVLVL 169
            :|||...|.      ||......|......|..|..::..||.      :.|:.||......:.|
  Fly     2 TRWPFNLLL------LLSVAVRDCSNHRTVLTVGYLTALTGDL------KTRQGLAISGALTMAL 54

  Rat   170 --LPRDDSYLFSLARVRPAIEYALRSVEGNGTGRKLLPPGTRFQVAYEDSDCGNRALFSLV-DRV 231
              :.:|.:.|       |.:...||..:..|                 |:....:|:..:: |.:
  Fly    55 DEVNKDPNLL-------PNVYLDLRWNDTKG-----------------DTVLATKAITEMICDGI 95

  Rat   232 AAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDTEY-----SHLTRVAPA 291
            |...|.:     || | |..|.|::..   ::||:|         :|..||     ....|..|.
  Fly    96 ATIFGPE-----GP-C-YVEAIVSQSR---NIPMIS---------YKCAEYRASAIPTFARTEPP 141

  Rat   292 YAKMGEMMLALFRHHHWSRAALLYSDDKLERNCYFTLEGVHEVFQEEGL-------HTSAYNFDE 349
            ..::.:.:|||.|::.|::.::||.|         ....|.::.:::..       |..::..:.
  Fly   142 DTQVVKSLLALLRYYAWNKFSILYED---------VWSPVADLLKDQATKRNMTINHKQSFIDNR 197

  Rat   350 TKDLD--LD--------DIVRYIQGSERVVIMCASGDTIRRIMLAVHRHGM-TSGDYAFFNIELF 403
            .|..:  ||        .:|:......|:.:...:.:::...|.::...|: ..|:|....:::.
  Fly   198 VKCCEQMLDCCRSGYWYQLVQNTMNRTRIYVFLGAANSLVDFMSSMETAGLFARGEYMVIFVDMM 262

  Rat   404 -NSSSYGDGSWKRGDKHDF----EAKQAYSSLQTVTLLRTAKP---EFEKFSMEVKSSVEKQGLN 460
             .|....:...:|.|:..|    .:.:.::.:....|:..:.|   ::.:|:.:|:....|...|
  Fly   263 VYSEREAEKYLRRVDQITFMSNCHSTENFNQMARSLLVVASTPPTKDYIQFTKQVQKYSSKPPFN 327

  Rat   461 EE-----------DYVNMFVEGFHDAILLYVLALHEVLRAGYS----------KKDGGKIIQQ-T 503
            .|           .:::::....:|::.||..|:.::||....          ..:|.::|.. .
  Fly   328 LEIPRLFVESNFSKFISIYAAYLYDSVKLYAWAVDKMLREETRVLTDDVIFEVASNGTRVIDTII 392

  Rat   504 WNRTFEGIAG-QVSIDANGDRYGDFSVVA--------MTDTEAGTQEVIGDYF--GKE-GRFKM- 555
            .|||:..|.| ::.||..||..|:|||:|        ..:.......|...||  |:| ..:|:
  Fly   393 KNRTYMSITGSKIKIDQYGDSEGNFSVLAYKPHKWNNSNNMPCNYHMVPVAYFHQGEEHPEYKLI 457

  Rat   556 RSNVKYPWGSLKLRIDETRIVEHTNSSPCKSSGGLEESAVTGIVVGALL--GAGLLMAFYFFRKK 618
            ..::.:|.|..| ..||. :....|.. ||.......|.|..:|:|.||  ...:.|:.|   :|
  Fly   458 NGSIDWPSGGEK-PADEP-MCGFANEL-CKKDDTHYTSTVAAVVLGVLLFCSGVITMSIY---RK 516

  Rat   619 YRITIE 624
            ::|.:|
  Fly   517 WKIELE 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Npr3	XP_006232107.1	PBP1_NPR_C_like	165..556	CDD:107381	84/459 (18%)
		ANF_receptor	182..535	CDD:279440	75/415 (18%)
		TM_EphA1	587..618	CDD:214014	8/32 (25%)
Gyc76C	NP_001163473.1	PBP1_Speract_GC_like	26..445	CDD:107365	86/476 (18%)
		ANF_receptor	48..412	CDD:279440	71/415 (17%)
		PK_GC-A_B	543..827	CDD:270944
		HNOBA	<835..881	CDD:285003
		CYCc	860..1052	CDD:214485
		Guanylate_cyc	887..1074	CDD:278633

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810