Protein Alignment HEPACAM2 and ketn-1

DIOPT Version :9

• Sequence 1: NP_001275733.1
• Gene: HEPACAM2 / 253012
• HGNCID: 27364
• Length: 485
• Species: Homo sapiens
• Sequence 2: NP_001294668.1
• Gene: ketn-1 / 178740
• WormBaseID: WBGene00004130
• Length: 4963
• Species: Caenorhabditis elegans
• Alignment Length: 282
• Identity: 57/282 - (20%)
• Similarity: 99/282 - (35%)
• Gaps: 49/282 - (17%)

Human    64 VHGVRGQALYLPVHYGFHTPASDIQIIWLFERPHTMPKYLLGSVNKSVVPDLEYQHKFTMMPPNA 128
            :.|..|:|....:.:   ..|:.:::.||.:          |...||.     ::...|..|.|:
 Worm  4555 LQGELGKAAKFVIEF---AGAAPVKVTWLKD----------GKEIKST-----FRTLITTTPTNS 4601

Human   129 SLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTK---PVVQIHPPSGAVEYVGNMT 190
            ||.|..|:....|.|.|::.   |...:......:||..|.|:   |..........::..|...
 Worm  4602 SLHIGRLENSHAGEYTVRLE---NAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAE 4663

Human   191 LTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNT--LHIAPVTKEDIGNYSCLVRNPVSEMES 253
            .:|.:.|..:...||.|:|:|:.....:....:...  |..:.:...|.|.|..:.:|.|.|...
 Worm  4664 FSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEARC 4728

Human   254 DIIMPIIYYGPYGLQVNSDKGLKVG------------EVFTVDLGEAILFDCSADSHPPNTYSWI 306
            ...:.:      .|| .:.||.:.|            :...||.|:...|.......|..|..|.
 Worm  4729 KARLNV------NLQ-KTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRWY 4786

Human   307 RRTDNTTYIIKHGPRLEVASEK 328
            |..:.    :||....|::..|
 Worm  4787 RNNEP----VKHADGYEISQSK 4804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HEPACAM2	NP_001275733.1	Ig	128..>197	CDD:299845	15/71 (21%)
		I-set	172..255	CDD:254352	16/84 (19%)
		IGc2	190..249	CDD:197706	12/60 (20%)
ketn-1	NP_001294668.1	I-set	3720..3806	CDD:254352
		Ig	3740..3806	CDD:143165
		I-set	3821..3914	CDD:254352
		Ig	3822..3914	CDD:299845
		I-set	3962..4052	CDD:254352
		Ig	3989..4050	CDD:143165
		I-set	4098..4184	CDD:254352
		Ig	4105..4184	CDD:299845
		I-set	4546..4635	CDD:254352	20/100 (20%)
		Ig	4567..4635	CDD:299845	17/88 (19%)
		I-set	4645..4734	CDD:254352	16/88 (18%)
		Ig	4662..4734	CDD:299845	14/71 (20%)
		I-set	4752..4839	CDD:254352	12/57 (21%)
		Ig	4769..4838	CDD:143165	9/40 (23%)
		I-set	4872..4960	CDD:254352
		Ig	4875..4960	CDD:299845
		I-set	18..106	CDD:254352
		Ig	21..101	CDD:299845
		I-set	136..224	CDD:254352
		Ig	153..218	CDD:299845
		I-set	303..393	CDD:254352
		Ig	305..387	CDD:299845
		Ig	705..795	CDD:299845
		I-set	706..797	CDD:254352
		I-set	806..894	CDD:254352
		IGc2	820..884	CDD:197706
		I-set	937..1028	CDD:254352
		Ig	965..1025	CDD:143165
		I-set	1065..1156	CDD:254352
		Ig	1092..1153	CDD:143165
		I-set	1190..1281	CDD:254352
		Ig	1218..1279	CDD:143165
		I-set	1328..1420	CDD:254352
		Ig	1361..1416	CDD:299845
		I-set	1462..1554	CDD:254352
		Ig	1463..1543	CDD:299845
		I-set	1595..1685	CDD:254352
		Ig	1616..1685	CDD:143165
		I-set	1728..1816	CDD:254352
		Ig	1755..1816	CDD:143165
		IG_like	1872..1953	CDD:214653
		Ig	1872..1948	CDD:299845
		I-set	1993..2085	CDD:254352
		IGc2	2008..2076	CDD:197706
		I-set	2126..2217	CDD:254352
		IGc2	2140..2208	CDD:197706
		I-set	2258..2351	CDD:254352
		Ig	2286..2348	CDD:143165
		DUF1136	2357..2382	CDD:284093
		I-set	2391..2482	CDD:254352
		IGc2	2413..2472	CDD:197706
		DUF1136	2488..2514	CDD:284093
		Ig	2521..2615	CDD:299845
		I-set	2522..2612	CDD:254352
		DUF1136	2620..2645	CDD:284093
		I-set	2654..2746	CDD:254352
		Ig	2682..2743	CDD:143165
		DUF1136	2752..2776	CDD:284093
		IG_like	2799..2878	CDD:214653
		Ig	2805..2876	CDD:143165
		DUF1136	2885..>2905	CDD:284093
		I-set	2919..3011	CDD:254352
		Ig	2949..3011	CDD:299845
		I-set	3051..3141	CDD:254352
Ig	3078..3139	CDD:143165
I-set	3182..3274	CDD:254352
Ig	3204..3270	CDD:299845
IG	3327..3406	CDD:214652
Ig	3343..3403	CDD:143165
I-set	3448..3539	CDD:254352
Ig	3476..3537	CDD:143165
I-set	3584..3676	CDD:254352
Ig	3602..3673	CDD:143165

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910