DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FUT7 and FucTA

DIOPT Version :9

Sequence 1:	NP_004470.1	Gene:	FUT7 / 2529	HGNCID:	4018	Length:	342	Species:	Homo sapiens
Sequence 2:	NP_001261872.1	Gene:	FucTA / 39653	FlyBaseID:	FBgn0036485	Length:	503	Species:	Drosophila melanogaster

Alignment Length:	301	Identity:	92/301 - (30%)
Similarity:	141/301 - (46%)	Gaps:	47/301 - (15%)

- Green bases have known domain annotations that are detailed below.

Human    64 PSDTCTRYGIARCHLSANRSLLASADAVVFHHRELQTRRSHLPLAQRPRGQPWVWASM----ESP 124
            |.||        |.|:|||.|.::||.:::....:.|.      .:||.....|  ||    |.|
  Fly   201 PVDT--------CELTANRDLASTADMILYKDHYIPTG------IRRPSNSKQV--SMLYYLECP 249

Human   125 SHTHGLSHLRGIFNWVLSYRRDSDIFVPYGRLEPH------------WGPSPPLPAKSRVAAWVV 177
            .||..:. :....||..:|||||.|..||.:.:.:            :..:     |::..||.|
  Fly   250 YHTQNVK-VPDAINWTATYRRDSTIVAPYEKWQYYDTKVQQQEQDINYSVN-----KTKKVAWFV 308

Human   178 SNFQERQLRARLYRQLAPHLRVDVFGRANGRPLCA-----SCLVPTVAQYRFYLSFENSQHRDYI 237
            ||...|..|.:...:|..::.||::| |.|...|:     .|.......|:|||:||||..:|||
  Fly   309 SNCGARNGRLQYAHELQKYIEVDIYG-ACGNFKCSRSTADKCFEILDNDYKFYLAFENSNCKDYI 372

Human   238 TEKFWRNALVAGTVPVVLGPPRATYEAFVPADAFVHVDDFGSARELAAFLTGM--NESRYQRFFA 300
            ||||:.|||....:|:|:|.....||...|..:::|||:|.|.:|||.:|..:  ::..|..:|.
  Fly   373 TEKFFVNALNRRVLPIVMGARPEDYEVSAPRRSYIHVDEFSSPKELAEYLRILDHDDELYNSYFK 437

Human   301 WRDRLRVRLFTDWRERFCAICDRYPHLPRSQVYEDLEGWFQ 341
            |:..... :.|.:..|.||.......|.:.:.|.||..|::
  Fly   438 WKGTGEF-INTYYWCRVCATLHNEEQLRKPRWYTDLNDWWR 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FUT7	NP_004470.1	Glyco_tran_10_N	44..154	CDD:319100	30/93 (32%)
FUT7	NP_004470.1	Glyco_transf_10	169..337	CDD:307136	59/174 (34%)
FucTA	NP_001261872.1	Glyco_tran_10_N	173..277	CDD:293644	29/92 (32%)
FucTA	NP_001261872.1	Glyco_transf_10	300..473	CDD:279224	59/174 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	123	1.000	Domainoid score	I5576
eggNOG	1	0.900	-	-		E1_KOG2619
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I4402
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D394490at33208
OrthoFinder	1	1.000	-	-		FOG0000215
OrthoInspector	1	1.000	-	-		mtm8516
orthoMCL	1	0.900	-	-		OOG6_100170
Panther	1	1.100	-	-	O	PTHR11929
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3232
SonicParanoid	1	1.000	-	-		X114
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.860