Protein Alignment Slc5a11 and CG31262

DIOPT Version :10

• Sequence 1: NP_001093952.2
• Gene: Slc5a11 / 252854
• RGDID: 621410
• Length: 673
• Species: Rattus norvegicus
• Sequence 2: NP_732222.2
• Gene: CG31262 / 318649
• FlyBaseID: FBgn0051262
• Length: 579
• Species: Drosophila melanogaster
• Alignment Length: 632
• Identity: 144/632 - (22%)
• Similarity: 245/632 - (38%)
• Gaps: 136/632 - (21%)

  Rat    28 DIVVLVLYFLFVLAVGLWSTVRTKR------------------DTVKGYFLAGGDMVWWPVGASL 74
            |.:|||...|.....|::.....|:                  :.:..|.:...:|...||..:|
  Fly    10 DYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNMKVIPVSITL 74

  Rat    75 F--ASNVGSG----HFIGLAGSGAAVGISVAAYELNGLFSVLMLAWIFLPIYIAGQVTTMPEYLR 133
            :  .|.:|:.    |:      |....:.:.|..|.|    :..::::||:|.|.|:.:..|||.
  Fly    75 YRVTSIIGTPSEIYHY------GTQYYLIIVAIILQG----IAFSYVYLPVYSALQIGSAYEYLG 129

  Rat   134 RRFGGSRIPITLAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAVTA--LYTVAGG 196
            .|| .|.|..|.:.:|:| .|.|.:...:|..|:.:.|...|:.:|  :||:.:.|  .||..||
  Fly   130 LRF-NSIIRTTASFMYVF-GILTYLPFIVYVPALSLSQVSGLNTHL--IGLVIILACVTYTFMGG 190

  Rat   197 LAAVIYTDALQTVIMLIG----AFILMGYSFAAVGGMEGLKDQYFLALASNRSENSSCGLPREDA 257
            |.||::||..|..:|.:.    ||:.:.||...|...:..:....|.||:.   |.|
  Fly   191 LKAVVHTDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRLMLANT---NPS-------- 244

  Rat   258 FHIFRDPLTSDLPWPGILFGMSIPSLWYWCT----DQVIVQRSLAAKNLSHAKGGSLMAAYLKVL 318
                  |......|..::.|.|     :|.:    .|.:|||.::..:|..::..|.:......:
  Fly   245 ------PYVRHTVWSVLIGGFS-----FWTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIGVSI 298

  Rat   319 PLFLMVFPGMVSRILFPDQVACAHPDICQRVCSNPSGCSDIAYPKLVLELLPT-------GLRGL 376
            .:.|..|.|:   :||.....|           :|.....|.....:|.|...       |:.||
  Fly   299 FIALCCFMGL---LLFSKYKDC-----------DPRSAGMILNDDQLLPLFVVQSVGHIYGMPGL 349

  Rat   377 MMAVMVAALMSSLTSIFNSASTIFTMDL---WHHIRPRASERELMIVGRVFVLALVLVSILWIPV 438
            .:|.:..|.:|||:|.||:.|.:|..|:   :..:.|  |||:..|:.:..::...:::.|.:.:
  Fly   350 FIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFFKMEP--SERQSTILIKTCIIFQGILAFLIVFL 412

  Rat   439 VQASQGGQLFIYIQSISSYLQPPVAVVFIMGCFWKRTNEKG-AFSGLILGLLLGLVRLILDFVYV 502
            :|..:|  :.....||||........||.:|..:...|..| |..||...||.|.:.
  Fly   413 LQHLRG--ILSVCNSISSITAGTSFGVFTLGMLFPWANTIGTAVGGLSSVLLAGWIS-------- 467

  Rat   503 QPRCDQPDDRPAVVKDVHYLYFSMILSSTTLITVFTVSWFTETPSKEMVSRLTWFTRHEPVAQKD 567
                                :.|.|.:::..:.    |.......||.|..:|  ...:|...:|
  Fly   468 --------------------FGSQIAAASGQLK----SGMLPVSVKECVGNVT--LPEDPWVDQD 506

  Rat   568 SVPPENPLSL-TISQNG--TTEATGISIQLESVQEATTKAHSDGVSP 611
            .|.|...||. .:|..|  |....|..:.|.:........|::.:||
  Fly   507 QVFPLYRLSYHWVSPIGVVTAVVVGALVSLITKPADIKTLHAELISP 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc5a11	NP_001093952.2	SLC5-6-like_sbd	28..673	CDD:444915	144/632 (23%)
CG31262	NP_732222.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	137/599 (23%)