Protein Alignment Cyp24a1 and shd

DIOPT Version :9

• Sequence 1: NP_963966.1
• Gene: Cyp24a1 / 25279
• RGDID: 2462
• Length: 514
• Species: Rattus norvegicus
• Sequence 2: NP_001261843.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Alignment Length: 570
• Identity: 139/570 - (24%)
• Similarity: 244/570 - (42%)
• Gaps: 106/570 - (18%)

  Rat     3 CPIDKRRTLIAFLRRL-----------RDLGQPPRSVTSKASASRAPKEVPLCPLMTDGETRNVT 56
            |.:.:.:....:||.|           .:|.||           .|||.          ..|.:.
  Fly    17 CALHRHKLADIYLRPLLKNTLLEDFYHAELIQP-----------EAPKR----------RRRGIW 60

  Rat    57 SLPGPTNWPLLGS---LLEIFWKGGLKKQHDTLAEYHKKYGQI-FRMKLGSFDSVHLGSPSLLEA 117
            .:|||...|.||:   .|..|.:..:.|.|:..|:.:::||.| ..:...:...|||.:...||.
  Fly    61 DIPGPKRIPFLGTKWIFLLFFRRYKMTKLHEVYADLNRQYGDIVLEVMPSNVPIVHLYNRDDLEK 125

  Rat   118 LYRTESAHPQRLEIKPWKAYRDHRNEAY---GLMILEGQEWQRVRSAFQKKLMKPVEIMKLDKKI 179
            :.:..|.:|.|...:....||..|.:.|   |::..:|..|||:||:....:..|
  Fly   126 VLKYPSKYPFRPPTEIIVMYRQSRPDRYASVGIVNEQGPMWQRLRSSLTSSITSP---------- 180

  Rat   180 NEVLADFLERMDELCDE-----RGR-------IPDLYSELNKWSFESICLVLYEKRFGLLQKETE 232
             .||.:||..::.:||:     |.|       :|:.....|....|::|.::..:|.|.|..:|:
  Fly   181 -RVLQNFLPALNAVCDDFIELLRARRDPDTLVVPNFEELANLMGLEAVCTLMLGRRMGFLAIDTK 244

  Rat   233 --EEALTFITAIKTMM-----STFGKMMVTPVELHKRLNTKVWQAHTLAWDTIFKSVKPCIDNRL 290
              ::......|:|.:.     |.:|      :.|.|...||.::....|.|.|:..:...||:.|
  Fly   245 QPQKISQLAAAVKQLFISQRDSYYG------LGLWKYFPTKTYRDFARAEDLIYDVISEIIDHEL 303

  Rat   291 QRYSQQPGAD----------FLCDIYQQDHLSKKELYAAVTELQLAAVETTANSLMWILYNLSRN 345
            :...:....:          || :|.:...|..::..:|:.:...|.:||.||:|:::|.:::.:
  Fly   304 EELKKSAACEDDEAAGLRSIFL-NILELKDLDIRDKKSAIIDFIAAGIETLANTLLFVLSSVTGD 367

  Rat   346 PQAQRRLLQEV-----QSVLPDNQTPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKPTVLG 405
            |.|..|:|.|.     .::|.|       .|.|..|.|||::||.||.|:.....|.|::...|.
  Fly   368 PGAMPRILSEFCEYRDTNILQD-------ALTNATYTKACIQESYRLRPTAFCLARILEEDMELS 425

  Rat   406 EYALPKGTVLTLNTQVLGSSEDNFEDSHKFRPERWLQKEKK------INPFAHLPFGIGKRMCIG 464
            .|:|..|||:.....:....:.||:.:.:|.||||:....:      .|....:|||:|:|.|.|
  Fly   426 GYSLNAGTVVLCQNMIACHKDSNFQGAKQFTPERWIDPATENFTVNVDNASIVVPFGVGRRSCPG 490

  Rat   465 RRLAELQLHLALCWIIQKYDIVATDNEPVEMLHLGILVPSRELPIAFRPR 514
            :|..|:::.|.|..::..:|:...  :|:|.....:|.|...|.:....|
  Fly   491 KRFVEMEVVLLLAKMVLAFDVSFV--KPLETEFEFLLAPKTPLSLRLSDR 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp24a1	NP_963966.1	CYP24A1	90..508	CDD:410738	115/461 (25%)
shd	NP_001261843.1	p450	63..528	CDD:299894	125/491 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820