Protein Alignment Mapk10 and p38b

DIOPT Version :9

• Sequence 1: NP_001305119.1
• Gene: Mapk10 / 25272
• RGDID: 3663
• Length: 478
• Species: Rattus norvegicus
• Sequence 2: NP_477361.1
• Gene: p38b / 34780
• FlyBaseID: FBgn0024846
• Length: 365
• Species: Drosophila melanogaster
• Alignment Length: 358
• Identity: 163/358 - (45%)
• Similarity: 234/358 - (65%)
• Gaps: 22/358 - (6%)

  Rat    47 QFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRE 111
            :||.:::..:.:.:.:.||||:|:|.||.|.||.|........||||||:||||:..||||.|||
  Fly     7 KFYKLDINRTEWEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRE 71

  Rat   112 LVLMKCVNHKNIISLLNVF---TPQKTLEEFQDVYLVMELMDANLCQVIQ-MELDHERMSYLLYQ 172
            |.|:|.::|:|:|.||:||   .|..:|::||.||:|..||||:|..:|: .:|..:.:.:|:||
  Fly    72 LRLLKHMDHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDHVQFLVYQ 136

  Rat   173 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILG 237
            :|.|:|::||||:||||||||||.|..||.|:||||||||.|.:.  ||.||.||:|||||::|.
  Fly   137 ILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPAESE--MTGYVATRWYRAPEIMLN 199

  Rat   238 -MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRNYVEN 300
             |.|.:..|||||||||.|::..:.||||.|:|.|.|.::|.||||..|||.:: ..:.|||:.:
  Fly   200 WMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESARNYIRS 264

  Rat   301 RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP 365
            .|......|..:|..:        |.|    |.|||.|||.:|..|||:.:.||.|||:..::||
  Fly   265 LPVMPRRNFRDIFRGA--------NPL----AIDLLEKMLELDADKRITAEQALAHPYMEKYHDP 317

  Rat   366 AEVEAPPPQIYDKQLDEREHTIEEWKELIYKEV 398
            .:.:.  ..:||:..:|.|..:|:|:|:::.||
  Fly   318 TDEQT--AALYDQSFEENELPVEKWREMVFSEV 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mapk10	NP_001305119.1	STKc_JNK	63..398	CDD:270840	159/340 (47%)
		S_TKc	64..359	CDD:214567	149/300 (50%)
p38b	NP_477361.1	STKc_p38	8..353	CDD:143356	163/357 (46%)
		S_TKc	24..311	CDD:214567	149/300 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910