Protein Alignment X11L and Pard3

DIOPT Version :9

• Sequence 1: NP_001285376.1
• Gene: X11L / 252671
• FlyBaseID: FBgn0026313
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: XP_006531583.1
• Gene: Pard3 / 93742
• MGIID: 2135608
• Length: 1337
• Species: Mus musculus
• Alignment Length: 739
• Identity: 152/739 - (20%)
• Similarity: 238/739 - (32%)
• Gaps: 254/739 - (34%)

  Fly   522 EIADASESMTMVPDADNPLDSHYGAVYAAALGGTHTEKSAGSGLGVTPVTAGGSLPSQAASEIQE 586
            ::||..:.:..|.|..:|  .|.|...:|:..||.:.:..||.||...|:|  ..|.||.|||
Mouse    67 DVADDKDRLVAVFDEQDP--HHGGDGTSASSTGTQSPEIFGSELGTNNVSA--FQPYQATSEI-- 125

  Fly   587 AMKEIRSALQRAKTQPEKLKFCDEVLPTDPDSPVWVPRKGTTISTAQGAAADEEPDTDLETDRLL 651
               |:..::.||                  :.|:.|.|
Mouse   126 ---EVTPSVLRA------------------NMPLHVRR--------------------------- 142

  Fly   652 GQQRHDEQDFFADQSLADNNANEGTDIASNGHLNGTSDNN----NPNPMNNSKPQTYSTATIRQG 712
                                   .:|.|..|.....||||    .|:..|   |..:||..   |
Mouse   143 -----------------------SSDPALTGLSTSVSDNNFSSEEPSRKN---PTRWSTTA---G 178

  Fly   713 IGTSLTPNSPDICQIVGTTDISISSPEKLQFTKSPTG-SIKSLKDSANSDKKA-----------K 765
            .....|..||..|.  ...|.:..|     ..:.|:. |.:..:|:|.|...|           :
Mouse   179 FLKQNTAGSPKTCD--RKKDENYRS-----LPRDPSSWSNQFQRDNARSSLSASHPMVDRWLEKQ 236

  Fly   766 SRNKEGLLEPKVLIEGVLFRARYLGSTQLVCEGQPTKSTRMMQAEEAVSR--------------- 815
            .:::||..|....:|.|       |......|..|..|...|.....|..
Mouse   237 EQDEEGTEEDSSRVEPV-------GHADTGLENMPNFSLDDMVKLVQVPNDGGPLGIHVVPFSAR 294

  Fly   816 --------IKALAPEGESQPSTEVDLFISTEKIMVLNT-DLKEIMMD---HALRTISYIADIGDL 868
                    :|.|...|:::   :.:||...:.|:.:|. ||:....:   |..|.......|...
Mouse   295 GGRTLGLLVKRLEKGGKAE---QENLFHENDCIVRINDGDLRNRRFEQAQHMFRQAMRARVIWFH 356

  Fly   869 VVLMARR-----------------RFVPNS--VVDPSI--TSPLGDVPTPGIGEEESPPKEPLSK 912
            ||..|.:                 ||.|:|  |.:.|:  .:|......|.:    |.|.|.|..
Mouse   357 VVPAANKEQYEQLSQREKNNYSPGRFSPDSHCVANRSVANNAPQALPRAPRL----SQPPEQLDA 417

  Fly   913 HNRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIENESLAKEMDYQEVLNSQEIFGDE 977
            |.|.|.. .|......|         |..:|....|..|            ...|.|:::: |..
Mouse   418 HPRLPHS-AHASTKPPA---------APALAPPSVLSTN------------VGSVYNTKKV-GKR 459

  Fly   978 LEIFAKKELQKEVVVPKAKGEILGVVIV--ESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLI 1040
            |.|..||..           |.||..|.  :...|...| :.:.|::..|||.:.|:|..||:||
Mouse   460 LNIQLKKGT-----------EGLGFSITSRDVTIGGSAP-IYVKNILPRGAAIQDGRLKAGDRLI 512

  Fly  1041 AINGMSLVGLPLSTCQSYIRNAKNQTAVKFTV------------------VPCPPVVEVK----I 1083
            .:||:.|.|.......|.:|:.|.:..|...|                  :..|...:.:    :
Mouse   513 EVNGVDLAGKSQEEVVSLLRSTKMEGTVSLLVFRQEEAFHPREMNAEPSQMQTPKETKAEDEDVV 577

  Fly  1084 LRPKALFQ---------------LGFSVQN----------GV-ICSLLRGGIAERGG-VRVGHRI 1121
            |.|....:               ||.||:.          |: :.|::.||.|.:.| :||..::
Mouse   578 LTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQL 642

  Fly  1122 IEINNQSVVAVPHDTIVKLLSSSV 1145
            |.:|.:|::...:...::.|..|:
Mouse   643 IAVNGESLLGKANQEAMETLRRSM 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
X11L	NP_001285376.1	PTB_X11	775..954	CDD:269919	44/226 (19%)
		PDZ_signaling	988..1065	CDD:238492	23/78 (29%)
		PDZ_signaling	1092..1151	CDD:238492	17/66 (26%)
Pard3	XP_006531583.1	DUF3534	2..83	CDD:338230	4/15 (27%)
		PDZ_signaling	272..347	CDD:238492	12/77 (16%)
		PDZ_signaling	465..544	CDD:238492	26/90 (29%)
		PDZ_signaling	588..681	CDD:238492	17/79 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900