Protein Alignment X11L and Apba3

DIOPT Version :9

• Sequence 1: NP_001285376.1
• Gene: X11L / 252671
• FlyBaseID: FBgn0026313
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: XP_006241080.1
• Gene: Apba3 / 83611
• RGDID: 620846
• Length: 636
• Species: Rattus norvegicus
• Alignment Length: 692
• Identity: 247/692 - (35%)
• Similarity: 349/692 - (50%)
• Gaps: 153/692 - (22%)

  Fly   507 LPMPPAPPPSSPPQIEIADASESMTMVPDADNPLDSHYGAVYAAALG--GTHTEKSAGSGLGVTP 569
            ||.|..||  .||.:::.:...  ..||..|:|.::.:      |||  |..|
  Rat     4 LPEPQHPP--GPPTMDLEEPKG--PEVPSEDHPSNTQW------ALGPRGPDT------------ 46

  Fly   570 VTAGGSLPSQAASEIQEAMKEIRSALQRAKTQPEKLKFCDEVLPTD-----PDS---PVWVPRKG 626
                       .||::.....:|:.:|:.           |.||:|     ||.   |:
  Rat    47 -----------LSEMELDTSSVRALVQQL-----------EALPSDLGGQFPDGAPCPL------ 83

  Fly   627 TTISTAQGAAADEEPD------TDLETDRLLGQQRHDEQDFFADQSLADNNANEGTDI------- 678
             .|:|.||.|..|..|      .:...|.|||..|.:..  ...||:..:.|.....:
  Rat    84 -HIATGQGLATQENLDAGGLLSAEAGGDNLLGLLRCEAS--LPAQSVPPDPAQAAPRLLQPPEDP 145

  Fly   679 -ASNGHLNGTSDNNNPNPMNNSKPQTY-STATIRQGIGTSLTPNSPDICQIVGT-TDISISSPEK 740
             ...|.:.||...:|.:  ::|.|:.: .||.:       :|...|.    ||| :..:::|...
  Rat   146 GGDPGWMEGTEPADNRS--SSSSPELWLETAPL-------VTHRDPP----VGTQSQETLASCPA 197

  Fly   741 LQFTKSPTGSIKSLKDSANSDKKAKSRNKEGLLEPKVLIEGVLFRARYLGSTQLVCEGQPTKSTR 805
            :.....|.|.                         :.|::||||.|:|||||||:.|..|..|||
  Rat   198 VSEVPGPCGQ-------------------------EELMDGVLFGAKYLGSTQLLSERNPPPSTR 237

  Fly   806 MMQAEEAVSRIKALAPEGESQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVV 870
            |.||:||:.|:|  |||||:||.||||:||||:::.||..|.::.:|||||:|||||||||.::|
  Rat   238 MGQAQEAMDRVK--APEGETQPMTEVDIFISTKRVKVLAADSQDALMDHALQTISYIADIGPVLV 300

  Fly   871 LMARRRFVPNSVVDPSITSPLGDVPTPGIGEEESPPKEPLSKHNRTPKMICHVFESDEAQFIAQS 935
            ||||||....:      ||.                    .:..:..||:||||.|::||.|||:
  Rat   301 LMARRRLAKRT------TSQ--------------------DRQRQLYKMLCHVFHSEDAQLIAQA 339

  Fly   936 IGQAFQVAYMEFLKANGIENESLAKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEIL 1000
            |||||.:||.:||:.|.|:    ..::..|...::......:|:.|...:..:||.:.|..||.|
  Rat   340 IGQAFSIAYSQFLQENRID----PSQVGMQPSASASHPHNGDLDHFCNSQNCREVCIQKRPGEGL 400

  Fly  1001 GVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGMSLVGLPLSTCQSYIRNAKNQ 1065
            ||.:|||||||:|||.|||||:..|.|.|||.|:|||::.||||.|||||.|:.||:.:|..:..
  Rat   401 GVALVESGWGSLLPTAVIANLLHGGPAERCGALSIGDRVTAINGTSLVGLSLAACQAAVREVRRH 465

  Fly  1066 TAVKFTVVPCPPVVEVKILRPKALFQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVV 1130
            ::|..:::.||||....|.||....||||.|:||:|||||||..||||||||||||||:|.||||
  Rat   466 SSVTLSIIHCPPVTTAVIHRPHVREQLGFCVENGIICSLLRGSAAERGGVRVGHRIIEVNGQSVV 530

  Fly  1131 AVPHDTIVKLLSSS----VGEILMKTMPTSMFRLLTGQETPI 1168
            |:||..|::||:.:    ||.:.....|.:....|....:|:
  Rat   531 AMPHARIIQLLTETREVCVGHLTRSPDPVTNTLTLLPDSSPL 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
X11L	NP_001285376.1	PTB_X11	775..954	CDD:269919	88/178 (49%)
		PDZ_signaling	988..1065	CDD:238492	45/76 (59%)
		PDZ_signaling	1092..1151	CDD:238492	40/62 (65%)
Apba3	XP_006241080.1	PTB_X11	208..359	CDD:269919	89/182 (49%)
		PDZ_signaling	388..473	CDD:238492	46/84 (55%)
		PDZ_signaling	478..549	CDD:238492	43/70 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3605
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002645
OrthoInspector	1	1.000	-	-		mtm8963
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12345
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.870