Protein Alignment X11L and PDZD3

DIOPT Version :9

• Sequence 1: NP_001285376.1
• Gene: X11L / 252671
• FlyBaseID: FBgn0026313
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: XP_011541302.1
• Gene: PDZD3 / 79849
• HGNCID: 19891
• Length: 571
• Species: Homo sapiens
• Alignment Length: 442
• Identity: 85/442 - (19%)
• Similarity: 137/442 - (30%)
• Gaps: 166/442 - (37%)

  Fly   794 LVCEGQPTKSTRMMQAEEAVSRIKALAPEGESQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRT 858
            :||...|..|.:....:|.                         ::|:.:|.|    :::|.
Human   140 VVCRVDPGTSAQRQGLQEG-------------------------DRILAVNND----VVEHE--- 172

  Fly   859 ISYIADIGDLVVLMARRRFVPNSVVDPSITSPLGDVPTPGIGEEE------SPPKEPLSKHNRTP 917
                    |..|::.|.|.....|:...:.....||....:||:.      .|...|
Human   173 --------DYAVVVRRIRASSPRVLLTVLARHAHDVARAQLGEDAHLCPTLGPGVRP-------- 221

  Fly   918 KMICHVFESDEAQF-------------IAQSIGQAFQVAYM----EFLKANGIENESLAKEMDYQ 965
             .:||:.: ||..|             :..|.|.|.:.|.:    ..|:.||:..|........:
Human   222 -RLCHIVK-DEGGFGFSVTHGNQGPFWLVLSTGGAAERAGVPPGARLLEVNGVSVEKFTHNQLTR 284

  Fly   966 EVLNSQE-----IFGDELEIFAKKELQKEVVVPKAKG-------EILGVVIVESGWGSMLPTVVI 1018
            ::..|.:     :.|.|:|... ::|...:..|.|:|       ..|.:.....|:|.:|..
Human   285 KLWQSGQQVTLLVAGPEVEEQC-RQLGLPLAAPLAEGWALPTKPRCLHLEKGPQGFGFLLRE--- 345

  Fly  1019 ANLMSSGAAARCGQ---------------LNIGDQLIAINGMSLVGLPLSTCQSYIRNAKNQTAV 1068
                ..|...|.||               :..||:|:|:.|.|:.||......|.|:.  ..:.|
Human   346 ----EKGLDGRPGQFLWEVDPGLPAKKAGMQAGDRLVAVAGESVEGLGHEETVSRIQG--QGSCV 404

  Fly  1069 KFTVV------------------------PCPP-------VVEVK-------------------I 1083
            ..|||                        |..|       :||.:                   .
Human   405 SLTVVDPEADRFFSMVRLSPLLFLENTEAPASPRGSSSASLVETEDPSLEDTSVPSVPLGSRQCF 469

  Fly  1084 LRPKALFQLGF---SVQNG---VICSLLRGGIAERGGVRVGHRIIEINNQSV 1129
            |.|......||   .|.:|   .|..:..||.|.|.|::||..|:|:|...|
Human   470 LYPGPGGSYGFRLSCVASGPRLFISQVTPGGSAARAGLQVGDVILEVNGYPV 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
X11L	NP_001285376.1	PTB_X11	775..954	CDD:269919	32/182 (18%)
		PDZ_signaling	988..1065	CDD:238492	21/98 (21%)
		PDZ_signaling	1092..1151	CDD:238492	16/44 (36%)
PDZD3	XP_011541302.1	PDZ_signaling	113..193	CDD:238492	14/92 (15%)
		PDZ_signaling	221..298	CDD:238492	15/86 (17%)
		PDZ	326..411	CDD:214570	22/93 (24%)
		PDZ_signaling	466..545	CDD:238492	18/56 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900