DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment X11L and Slc9a3r2

DIOPT Version :9

Sequence 1:	NP_001285376.1	Gene:	X11L / 252671	FlyBaseID:	FBgn0026313	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	NP_075542.2	Gene:	Slc9a3r2 / 65962	MGIID:	1890662	Length:	337	Species:	Mus musculus

Alignment Length:	188	Identity:	39/188 - (20%)
Similarity:	63/188 - (33%)	Gaps:	72/188 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly  1025 GAAARCGQLNIGDQLIAINGMSLVGLPLSTCQSYIRNAKNQTAVKFTVV---------------- 1073
            |:.|....|..||:|:.:||:::.|.........|:..:.||  :..||
Mouse    42 GSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQT--QLLVVDKETDEELCRRQLTCT 104

  Fly  1074 ---------------------PC---------------PPVVEVKILRPKALFQL-------GFS 1095
                                 .|               ||    :.|||: |..|       ||:
Mouse   105 EEMAHRGLPPAHNPWEPKPDWACSGSLGSDTGQKDVNGPP----RELRPR-LCHLRRGPQGYGFN 164

  Fly  1096 VQNG------VICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHDTIVKLLSSSVGE 1147
            :.:.      .|.|:..|..|...|:|...|:||:|.|:|..:.|..:|..:.:...|
Mouse   165 LHSDKSRPGQYIRSVDPGSPASHSGLRAQDRLIEVNGQNVEGLRHAEVVARIKAQEDE 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
X11L	NP_001285376.1	PTB_X11	775..954	CDD:269919
		PDZ_signaling	988..1065	CDD:238492	10/39 (26%)
		PDZ_signaling	1092..1151	CDD:238492	18/69 (26%)
Slc9a3r2	NP_075542.2	PDZ_signaling	9..88	CDD:238492	12/47 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	112..147		3/38 (8%)
		PDZ	148..230	CDD:214570	21/76 (28%)
		EBP50_C	232..337	CDD:286142
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	242..337
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900