Protein Alignment X11L and Pdzk1

DIOPT Version :9

• Sequence 1: NP_001285376.1
• Gene: X11L / 252671
• FlyBaseID: FBgn0026313
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: NP_001139473.1
• Gene: Pdzk1 / 59020
• MGIID: 1928901
• Length: 519
• Species: Mus musculus
• Alignment Length: 524
• Identity: 96/524 - (18%)
• Similarity: 172/524 - (32%)
• Gaps: 168/524 - (32%)

  Fly   757 SANSDKKAKSRNKEG-----LLEPKVLIEGVLFRARYLGSTQLVCEGQPTKSTRMMQAEEAVSRI 816
            |..:.::.|...:||     .|..:...:|.|.|        ::.||.|.:...::..:. |.||
Mouse     3 STFNPRECKLSKQEGQNYGFFLRIEKDTDGHLIR--------VIEEGSPAEKAGLLDGDR-VLRI 58

  Fly   817 KALAPEGES---------QPSTEVDLFI----STEKIMVLNTDLKEIMMDHALRTISYIADIGDL 868
            ..:..:.|.         :....|.|.:    |.||.:....||||  :|.:.|.    |.:.|
Mouse    59 NGVFVDKEEHAQVVELVRKSGNSVTLLVLDGDSYEKAVKNQVDLKE--LDQSQRE----AALND- 116

  Fly   869 VVLMARRRFVPNSVVDPSITSPLGDVPTPGIGEEESPPKEPLSKHNRTPKMICH-VFESDEAQFI 932
                                    ..|.||:.....|..:|         .:|: |.|.:...|.
Mouse   117 ------------------------KKPGPGMNGAVEPCAQP---------RLCYLVKEGNSFGFS 148

  Fly   933 AQSI--------------GQAFQVAYM---EFLKANG--IENESLAKEMDYQEVLNSQEIFGDEL 978
            .::|              |.|.:...:   ..::.||  :||.|      ::||:......|..:
Mouse   149 LKTIQGKKGVYLTNIMPQGVAMKAGVLADDHLIEVNGENVENAS------HEEVVEKVTKSGSRI 207

  Fly   979 EIF------------AKKELQKEVVVPKAKGEILGVVIVE---SGWGSMLPT------VVIANLM 1022
            ...            .|.:.::|....|.......||:::   :|:|..|..      .:|.::
Mouse   208 MFLLVDKETARCHSEQKTQFKRETASLKLLPHQPRVVVIKKGSNGYGFYLRAGPEQKGQIIKDI- 271

  Fly  1023 SSGAAARCGQLNIGDQLIAINGMSLVGLPLSTCQSYIRNAKNQT--------------------- 1066
            ..|:.|....|...|.::|:||.|:..|........||...:||
Mouse   272 EPGSPAEAAGLKNNDLVVAVNGKSVEALDHDGVVEMIRKGGDQTTLLVLDKEAESIYSLARFSPL 336

  Fly  1067 -----------AVKFTVVPCP---------PVVEVKILRPKALFQL------GFSVQ------NG 1099
                       :||....|.|         |..:.:..:||....|      ||.:.      ..
Mouse   337 LYCQSQELPNGSVKEGPAPIPAPLEATGSEPTEDAEGHKPKLCRLLKEDDSYGFHLNAIRGQPGS 401

  Fly  1100 VICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHDTIVKLLSSSVGEILMKTMPTSMFRLLTGQ 1164
            .:..:.:||.|::.|:.....|||:|.::|...|:|.:|:.:.||...:.:.......:.....:
Mouse   402 FVKEVQQGGPADKAGLENEDVIIEVNGENVQEEPYDRVVERIKSSGKHVTLLVCGKMAYSYFQAK 466

  Fly  1165 ETPI 1168
            :.||
Mouse   467 KIPI 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
X11L	NP_001285376.1	PTB_X11	775..954	CDD:269919	37/211 (18%)
		PDZ_signaling	988..1065	CDD:238492	19/85 (22%)
		PDZ_signaling	1092..1151	CDD:238492	17/70 (24%)
Pdzk1	NP_001139473.1	PDZ_signaling	7..87	CDD:238492	16/88 (18%)
		PDZ	132..212	CDD:214570	16/94 (17%)
		PDZ_signaling	242..320	CDD:238492	19/78 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	348..374		5/25 (20%)
		PDZ_signaling	376..455	CDD:238492	19/78 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	479..519

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810