Protein Alignment X11L and apba1b

DIOPT Version :9

• Sequence 1: NP_001285376.1
• Gene: X11L / 252671
• FlyBaseID: FBgn0026313
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: XP_005155643.1
• Gene: apba1b / 565507
• ZFINID: ZDB-GENE-070925-3
• Length: 971
• Species: Danio rerio
• Alignment Length: 1132
• Identity: 367/1132 - (32%)
• Similarity: 513/1132 - (45%)
• Gaps: 327/1132 - (28%)

  Fly   196 AEYEGSPRRFGSQPNTNTITMGGPRKRP------------------------------------- 223
            |...|.|.....|||...:..|.||.||
Zfish    10 AGLRGPPPHRSKQPNGTPLEGGRPRWRPCQLHNPDAESQGQHHHHYHHQAHQHASGSSRAPPRHR 74

  Fly   224 ----PGFPQRVSPTTSVANNATAAAKASVGNLIDLVDHEEERSGTLREKTPTFDYLYEFSETRKV 284
                ||..||..| .|..:.|.|..:...|      ..:..|||   |:.    |.:.:.:..|.
Zfish    75 RRHVPGQAQRRRP-ESGDSEARAGQQPKPG------ASKHHRSG---ERL----YQHRYRQQHKD 125

  Fly   285 LEEFFKANPEDEKRYTDYT-TESGDDVASSQPQEYPAT-------PMEQAYIGQRLARIPKDEL- 340
            .|:..|..|:::......: .:|..|:.:..||:.|.|       |........::.|.|:.|.
Zfish   126 EEQHVKTPPKEQASEPLLSPDDSSQDLLTPSPQDEPVTDELDESSPDLSHSSDTQINRDPEQEQA 190

  Fly   341 --------YMVHRSPTKKPPSD--------QNPSTAYQEHNDIELYIDSNSRSSG--------DL 381
                    ..|||...|.|..:        ::.||...|.:.:...|.|.||...        |:
Zfish   191 ESSVDQPEENVHREEFKNPCEEELVKVNEVEDLSTQIPEEDYVPPKIASKSRPESKRTSPLRVDV 255

  Fly   382 -----------------ADTELEANLRRH-----------SRNFTLSPETTDYDS----NCGDLD 414
                             :......:|||:           :.|:..:....::||    :.|||.
Zfish   256 PPFATSPHQIINKPFFQSPRSFPESLRRYNSDPKSYPTFFNNNYACTRNDKEFDSPRSHDEGDLS 320

  Fly   415 SLSNDINCPTDFGKLYTSMPVLEDGLSSGHASDTENNVSVV-----------------CDKQQSS 462
            .           .:.||      |.....|..|||.:::..                 ||.||..
Zfish   321 D-----------SEAYT------DSYPESHPKDTETDLNPAFEEPQAYEMNYSMSMDECDDQQDL 368

  Fly   463 QSQPVHEHNGNGERLENDYNVMSASLATLTTDASQSAL--ISDFASLPMPPAPPPSSPPQI--EI 523
            :.:| :.|:..|.||.: |:..|...|. :...|::.|  .|...|||:...|......::  ..
Zfish   369 EEEP-NPHSAVGSRLHH-YDEQSGDEAE-SFGRSRAHLRKTSSSTSLPLEVHPQDDETSEMTQNS 430

  Fly   524 ADASESMTMVPDADNPLDSHYGAVYAAALGGTHTEKSAGSGLGVTPVTAGGSLPSQAASEIQEAM 588
            .|..|.:..||:..:.:                ||....:|..|          |.|..:|:||:
Zfish   431 TDLQEEVEDVPEKQDQI----------------TESCKATGDAV----------SLAIRDIKEAI 469

  Fly   589 KEIRSALQRAKTQPEKLKFCDEVLPTDPDSPVWVPRKGTTISTAQGAAADEEPDTDLETDRLLGQ 653
            :|:::...|:...|:|:           ..||||.|:
Zfish   470 EEVKTKTVRSPYMPDKI-----------TEPVWVMRQ---------------------------- 495

  Fly   654 QRHDEQDFFADQSLADNNANEGTDIASNGHLNGTSDNNNPNPMNNSKPQTYSTATIRQGIGTSLT 718
                                   |:               :|:..|.||.:|            .
Zfish   496 -----------------------DV---------------SPVEESHPQIHS------------Y 510

  Fly   719 PNSPDICQIVGTTDISISSPE---KLQFTKSPTGSIKS----------LKDSANSDKKAKSR--- 767
            |.||  ||      ||.|||:   .:|..:.|.|:..|          |..:..|:::.||.
Zfish   511 PQSP--CQ------ISQSSPQYAAPIQDAEPPLGAESSGVLHQDQDQELCPNVPSEEQRKSLASF 567

  Fly   768 ----NKEGLLEPKVLIEGVLFRARYLGSTQLVCEGQPTKSTRMMQAEEAVSRIKALAPEG----- 823
                :..|..:|:.||:|::|.|.|||||||:.|..||||.||.||:||:||::....:.
Zfish   568 PTYVDVPGPCDPEDLIDGIIFAANYLGSTQLLSERTPTKSARMQQAQEAMSRVRTAQAQAKIRNK 632

  Fly   824 ---ESQP--STEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRFVPNSVV 883
               ||.|  .|||||||||::|.||:...::.||||.|||||||||||::|||||||:.:.:...
Zfish   633 QGTESGPPSCTEVDLFISTQRIKVLSAYTQDTMMDHPLRTISYIADIGNMVVLMARRKMIRSQSA 697

  Fly   884 DPSITSPLGDVPTPGIGEEESPPKEPLSKHNRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFL 948
            ..::.:            .|:....|.....|..|||||||||::||.|||||||||.|||.|||
Zfish   698 QENLDT------------AETQHTNPARDDRRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFL 750

  Fly   949 KANGIENESLAKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSML 1013
            :||||:.|.|: :.:|.::||:|:::.|:|..|:|.|..::|.:.|.||||||||||||||||:|
Zfish   751 RANGIDPEDLS-QREYSDLLNTQDMYNDDLIHFSKSENCRDVYIEKQKGEILGVVIVESGWGSIL 814

  Fly  1014 PTVVIANLMSSGAAARCGQLNIGDQLIAINGMSLVGLPLSTCQSYIRNAKNQTAVKFTVVPCPPV 1078
            |||:||:||..|.||:.|:||||||::.:||.||||||||||||.|:..|:|:.:|..:|.||||
Zfish   815 PTVIIASLMHGGPAAKSGRLNIGDQIMTVNGTSLVGLPLSTCQSIIKGLKSQSRIKMNIVRCPPV 879

  Fly  1079 VEVKILRPKALFQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHDTIVKLLSS 1143
            ..|.|.||...:|||||||||:||||:||||||||||||||||||||.|||||.||:.||.:||:
Zfish   880 TMVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSN 944

  Fly  1144 SVGEILMKTMPTSMFRLLTGQETPIYI 1170
            :||||.|||||.:|:||||.||.|:||
Zfish   945 AVGEIHMKTMPAAMYRLLTAQEQPVYI 971

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
X11L	NP_001285376.1	PTB_X11	775..954	CDD:269919	95/188 (51%)
		PDZ_signaling	988..1065	CDD:238492	52/76 (68%)
		PDZ_signaling	1092..1151	CDD:238492	47/58 (81%)
apba1b	XP_005155643.1	PTB_X11	579..757	CDD:269919	96/189 (51%)
		PDZ	790..873	CDD:278991	54/82 (66%)
		PDZ_signaling	879..952	CDD:238492	53/72 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	175	1.000	Domainoid score	I3583
eggNOG	1	0.900	-	-		E1_KOG3605
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	530	1.000	Inparanoid score	I1184
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6563
orthoMCL	1	0.900	-	-		OOG6_104247
Panther	1	1.100	-	-	O	PTHR12345
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1305
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.820