DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment X11L and tamalin

DIOPT Version :9

Sequence 1:	NP_001285376.1	Gene:	X11L / 252671	FlyBaseID:	FBgn0026313	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	NP_001035013.1	Gene:	tamalin / 558950	ZFINID:	ZDB-GENE-060312-30	Length:	382	Species:	Danio rerio

Alignment Length:	163	Identity:	41/163 - (25%)
Similarity:	64/163 - (39%)	Gaps:	37/163 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  1023 SSGAAARCGQLNIGD---------QLIAINGMSLVGLPLSTCQSYIRN-AKNQTAVKFTVVPCPP 1077
            :|..:..||.:|.|.         :.:|.:|.:|.           || .||....|:..:...|
Zfish    32 TSSKSDSCGIVNRGPSNSTEVYNYKTLAYSGGTLP-----------RNFKKNGGLQKWKPLAQSP 85

  Fly  1078 VVEVK--ILRPKALFQLGFSVQ---------NGV-----ICSLLRGGIAERGGVRVGHRIIEINN 1126
            ..:.|  ||..|.....||.:|         |.|     :|.:.....|...|::||..|..:|:
Zfish    86 EPQRKTVILEKKEEESFGFEIQTYGLHHQSENSVEMCTFVCKVHEDSPALLAGLKVGDTIASVND 150

  Fly  1127 QSVVAVPHDTIVKLLSSSVGEILMKTMPTSMFR 1159
            .||....|..||:|:.||...|.::|:.:...|
Zfish   151 TSVDGFRHKEIVQLIKSSGNNIRLETVYSDSIR 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
X11L	NP_001285376.1	PTB_X11	775..954	CDD:269919
		PDZ_signaling	988..1065	CDD:238492	11/51 (22%)
		PDZ_signaling	1092..1151	CDD:238492	21/72 (29%)
tamalin	NP_001035013.1	PDZ_signaling	90..175	CDD:238492	25/84 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900