Protein Alignment X11L and Pdzd3

DIOPT Version :9

• Sequence 1: NP_001285376.1
• Gene: X11L / 252671
• FlyBaseID: FBgn0026313
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: NP_573489.2
• Gene: Pdzd3 / 170761
• MGIID: 2429554
• Length: 498
• Species: Mus musculus
• Alignment Length: 494
• Identity: 104/494 - (21%)
• Similarity: 164/494 - (33%)
• Gaps: 170/494 - (34%)

  Fly   754 LKDSANSDKKAKSRNKEGLLEPKV-LIEGV-------LFRARYLGSTQLVCEGQPTKSTRMMQ-- 808
            |:|:|....|.|...:.|:..|.: |.|..       |.|.|:   ..|..|.:.|....:.|
Mouse     7 LRDTALLTLKFKFNPRLGIDNPVLSLAEDQDQSDPWNLHRPRF---CLLSKEEEKTFGFHLQQHL 68

  Fly   809 --AEEAVSRIKALAPEGESQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVL 871
              |:..|.|:.. ....:.|...|.|..::....:|.:.       |||: .:.||...|..|:|
Mouse    69 GKADHVVCRVDP-GTSAQRQGLREGDRILAVNNNIVAHE-------DHAV-VVRYIRASGPRVLL 124

  Fly   872 MARRRFV---------PNSVVDPSITSPLGDVPTPGIGEEESPPKEPLSKHNRTPKMICHVFESD 927
            ....:.|         .::.:.|  |.|.|..|                       .:|||.: |
Mouse   125 TVLAQHVHDVARVLQGSDAFLCP--TLPSGVRP-----------------------RLCHVVK-D 163

  Fly   928 EAQF-------------IAQSIGQAFQVAYM----EFLKANGIENESLAKEMDYQEVLNSQEIFG 975
            |..|             :..|.|.|.:.|.:    ..|:.||...|.|.    |.::.......|
Mouse   164 EGGFGFSVTHGSRGPFWLVLSAGGAAERAGVPPGARLLEVNGASVEKLT----YNQLNRKLWQSG 224

  Fly   976 DELEIF-AKKELQKE-------VVVPKAKG-------EILGVVIVESGWGSMLPTVVIANLMSSG 1025
            |::.:. |..|::::       :..|.|:|       ..|.:.....|:|.:|..       ..|
Mouse   225 DQVTLLVAGLEVEEQCHQLGMPLAAPLAEGWALPAKPRCLNIEKGPEGFGFLLRE-------EKG 282

  Fly  1026 AAARCGQ---------------LNIGDQLIAINGMSLVGL----------PLSTCQSYIRNAKNQ 1065
            ...|.||               :..||:|:|:.|.|:.||          ...:|.|.|  ..:.
Mouse   283 LDGRLGQFLWDVDPGLPADKAGMKAGDRLVAVAGESVDGLGHEETVSRIRAQGSCVSLI--VVDP 345

  Fly  1066 TAVKF--------------TVVPCPPVVEVKIL------RPKAL-----------------FQLG 1093
            .|.:|              |.:..||:.|.|.|      .|..|                 |:|
Mouse   346 EADRFFSMVRLSPLLFLENTEIAAPPLAETKDLPVEDTVEPSGLAGSCQCFLYPGPGGGYGFRL- 409

  Fly  1094 FSVQNG---VICSLLRGGIAERGGVRVGHRIIEINNQSV 1129
            ..|.:|   .|..:..||.|.|.|::||..::|:|...|
Mouse   410 CCVASGPCLFISQVTPGGSAARAGLQVGDTVLEVNGYPV 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
X11L	NP_001285376.1	PTB_X11	775..954	CDD:269919	44/216 (20%)
		PDZ_signaling	988..1065	CDD:238492	22/115 (19%)
		PDZ_signaling	1092..1151	CDD:238492	14/41 (34%)
Pdzd3	NP_573489.2	PDZ_signaling	47..127	CDD:238492	20/91 (22%)
		PDZ_signaling	155..232	CDD:238492	19/104 (18%)
		PDZ	260..345	CDD:214570	19/93 (20%)
		PDZ_signaling	407..471	CDD:238492	15/43 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900