Protein Alignment X11L and apba2a

DIOPT Version :9

• Sequence 1: NP_001285376.1
• Gene: X11L / 252671
• FlyBaseID: FBgn0026313
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: XP_021326395.1
• Gene: apba2a / 100330365
• ZFINID: ZDB-GENE-121107-1
• Length: 923
• Species: Danio rerio
• Alignment Length: 1039
• Identity: 336/1039 - (32%)
• Similarity: 474/1039 - (45%)
• Gaps: 271/1039 - (26%)

  Fly   280 ETRKVLEEF----FKANPEDEKRYTDYTTESGDDVASSQPQEYPATPMEQAYIGQRLARIPKDEL 340
            |||.|..|.    |.|.||..::.      |||       ::.|.  :|:|
Zfish     8 ETRSVAAELNPPAFSAVPEGREQL------SGD-------RDDPV--LEEA-------------- 43

  Fly   341 YMVHRSPTKKPPSDQNPSTAYQEHNDIELYIDSNSRSSGDLADTELEANLRRHSRNFTLSPETTD 405
                                  ||:.::....|.:.:...|:|...:.::|..|   .|.|::.:
Zfish    44 ----------------------EHDKLDCQTPSPTPAQYSLSDESGDDSIRGES---PLQPDSME 83

  Fly   406 YDS-----NCG--------------------DLDSLSNDIN-CPTDFGKLYTSMPVLEDGLSSGH 444
            .||     |.|                    :.|.::..:: ||.|...:        :||....
Zfish    84 EDSLSEYDNVGSGDEQEEVERDYEEDEELQTEADRMTYYVHCCPEDESYM--------EGLDCHE 140

  Fly   445 ASDTENNVSVVCDKQQSSQSQPVHEHNG----NGERLENDYNVMSASLATLTTDASQSALISDFA 505
            .:|.....|...|.::|.:.:...||:.    .|::.:         .||:.....:....:.|.
Zfish   141 GADGAECPSTSQDVRESCKPKEAWEHSDTSLCKGQQKD---------AATMVYKQPEPITETTFV 196

  Fly   506 SLPM--PPAPPPSSPPQIEIADASESMTMVPDADNPLDSHYGAVYAAALGGTHTEKSAGSGLGVT 568
            ..||  .......:...:|..|:.|.       ||....||....|.........|...|.:
Zfish   197 QAPMAEDEEDEEETEEDVEEEDSEEE-------DNGGFFHYEGNEAELNNNEIPHKDNCSNV--- 251

  Fly   569 PVTAGGSLPSQAASEI---------------------------QEAMKEIRS------------- 593
             ....|..|.|..|.:                           ::.|:.:|.
Zfish   252 -CRREGKSPPQEFSRVKVGQESRRSQDNPKYSRDVPLGSNCTQRDRMERVRDKNGSDCPKVSNAP 315

  Fly   594 -ALQRAKTQPEKLKFCDEVLPTDPDSPVWVPRKGTTISTAQGAAADEEPDTDLETDRLLGQQRHD 657
             |.:..|...:..|:....|.|..:..  ...:|.:..|.:|.:||.|       ||...::||
Zfish   316 VARESRKDSRQNFKYRGHHLETKNNRE--TAYQGHSAVTIKGKSADAE-------DRGTWKKRH- 370

  Fly   658 EQDFFADQSLADNNANEGTDIASNGHLNGTSDNN-------------NPNPMNNSKPQTYSTATI 709
                ....|..|....:|    :|.|....|..|             ..|..|..|......|.|
Zfish   371 ----LLKYSREDARGGDG----NNSHKRSKSPENCKNRPQDHPICSHKSNGENERKISGNVEARI 427

  Fly   710 RQGIGTSL--TPN-------SPDICQIV----------------------GTTDISISSPEKLQF 743
            ...:.|.|  .||       :||..:.|                      |..:..:.||.| |.
Zfish   428 ENEVKTKLIIAPNNSGRTKVAPDQAKNVKGAPESPRASSASSGKRNSKPRGQANTPVQSPAK-QV 491

  Fly   744 TKSPTGSIKSLKDSANSDKKAKSRNKE---------------------------GLLEPKVLIEG 781
            .|.....::..|...|.::.::|.:::                           |..||:.||.|
Zfish   492 NKDSAKPVEEEKTRPNEEQVSQSASQDSSTGPPSGQNRPQTQRNPSFPSFVDIPGPCEPEDLING 556

  Fly   782 VLFRARYLGSTQLVCEGQPTKSTRMMQAEEAVSRIKALAPEGESQPSTEVDLFISTEKIMVLNTD 846
            ::|.|.|||||||:.:..|:||.||.||:|||..:||:  |.|:|..||:||||||:.|.|||.|
Zfish   557 IIFAANYLGSTQLLSDRNPSKSVRMKQAQEAVDCVKAV--EVETQSLTEIDLFISTKAIKVLNAD 619

  Fly   847 LKEIMMDHALRTISYIADIGDLVVLMARRRFVPNSVVDPSITSPLGDVPTPGIGEEESPPKEPLS 911
            .:|.|||:||||||||||||::||||||||...:|:          |....|:..:
Zfish   620 TQETMMDNALRTISYIADIGNVVVLMARRRLSNSSL----------DCTESGLNSD--------- 665

  Fly   912 KHNRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIENESLAKEMDYQEVLNSQEIFGD 976
            .:::..:|||:||||::||.|||||||||.:||.|||:||||..:.|::: ||.::||:||::.|
Zfish   666 ANHKQYRMICYVFESEDAQLIAQSIGQAFSMAYQEFLRANGINPKDLSQK-DYSDILNTQEMYND 729

  Fly   977 ELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIA 1041
            :|..|:..:..|::.:.|.||||||||||||||||:||||::|.::::|.|||.|:||:|||::|
Zfish   730 DLVHFSNSDNCKQLHLEKQKGEILGVVIVESGWGSILPTVILACMLNNGPAARSGKLNVGDQIMA 794

  Fly  1042 INGMSLVGLPLSTCQSYIRNAKNQTAVKFTVVPCPPVVEVKILRPKALFQLGFSVQNGVICSLLR 1106
            :|..|||||||:.||..|:..||...||.:||.||||..|.|.||...:|||||||||:||||:|
Zfish   795 VNDTSLVGLPLAACQGIIKALKNHVQVKLSVVSCPPVTTVLIKRPDLQYQLGFSVQNGIICSLMR 859

  Fly  1107 GGIAERGGVRVGHRIIEINNQSVVAVPHDTIVKLLSSSVGEILMKTMPTSMFRLLTGQETPIYI 1170
            |||||||||||||||||||.|||||:.|:.||..||.|||||.|||||..|||||||||||:|:
Zfish   860 GGIAERGGVRVGHRIIEINGQSVVAMAHEKIVHALSVSVGEINMKTMPAVMFRLLTGQETPVYM 923

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
X11L	NP_001285376.1	PTB_X11	775..954	CDD:269919	94/178 (53%)
		PDZ_signaling	988..1065	CDD:238492	46/76 (61%)
		PDZ_signaling	1092..1151	CDD:238492	47/58 (81%)
apba2a	XP_021326395.1	CBF	<21..114	CDD:332044	23/146 (16%)
		PTB_X11	550..709	CDD:269919	95/179 (53%)
		PDZ	742..823	CDD:278991	47/80 (59%)
		PDZ_signaling	831..904	CDD:238492	53/72 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	175	1.000	Domainoid score	I3583
eggNOG	1	0.900	-	-		E1_KOG3605
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	530	1.000	Inparanoid score	I1184
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6563
orthoMCL	1	0.900	-	-		OOG6_104247
Panther	1	1.100	-	-	O	PTHR12345
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1305
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.860