DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sav and MAGIX

DIOPT Version :9

Sequence 1:	NP_788721.1	Gene:	sav / 252554	FlyBaseID:	FBgn0053193	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	NP_079135.3	Gene:	MAGIX / 79917	HGNCID:	30006	Length:	334	Species:	Homo sapiens

Alignment Length:	308	Identity:	59/308 - (19%)
Similarity:	99/308 - (32%)	Gaps:	98/308 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 RMRRQQSSPLL-----QTTSSPAPGAGGFQRSYSTTQRQHHP-HLGGDSYDADQGLLSASYANML 214
            |:||:::..:|     :.|.|..|.|         |...|.| |...::.:|.
Human    60 RLRRKEAVSVLDSADIEVTDSRLPHA---------TIVDHRPQHRWLETCNAP------------ 103

  Fly   215 QLPQRPHSPAHYAVPPQQQQ-HPQIHQQHASTPFGSTLRFDRAAMSIRERQPRYQPTSSPMQQQ- 277
              ||.....|..|..|.|.. |..:........||.||...|....           .:|:..:
Human   104 --PQLIQGKARSAPKPSQASGHFSVELVRGYAGFGLTLGGGRDVAG-----------DTPLAVRG 155

  Fly   278 --QQQQQQQQQQLQHTQLAAHLGGSYSSDSYPIYENPSRVISMRATQSQRSESPIYSNTTASSAT 340
              :....|:..:|:...|..|:.|          |:...:...:|.:..|:..|          .
Human   156 LLKDGPAQRCGRLEVGDLVLHING----------ESTQGLTHAQAVERIRAGGP----------Q 200

  Fly   341 LAVVPQHHHQGHLAVPSG------------------SGGGSLSGSGRGGSSGSVRGASTSVQSLY 387
            |.:|.:...:.|...|.|                  .||..::||         |.:|||:.. :
Human   201 LHLVIRRPLETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGS---------RSSSTSLVQ-H 255

  Fly   388 VPPRTPPSAVAGA-----GGSANGSLQKVPSQQSLTEPEELPLPPG-W 429
            .|.||......|:     ..:|:|.....|.:::....:::|..|| |
Human   256 PPSRTTLKKTRGSPEPSPEAAADGPTVSPPERRAEDPNDQIPGSPGPW 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sav	NP_788721.1	WW	425..454	CDD:278809	3/6 (50%)
MAGIX	NP_079135.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		PDZ_signaling	124..206	CDD:238492	17/112 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	209..306		22/105 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284488at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010