Protein Alignment sav and Sav1

DIOPT Version :10

• Sequence 1: NP_788721.1
• Gene: sav / 252554
• FlyBaseID: FBgn0053193
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_071311.1
• Gene: Sav1 / 64010
• MGIID: 1927144
• Length: 386
• Species: Mus musculus
• Alignment Length: 314
• Identity: 119/314 - (37%)
• Similarity: 155/314 - (49%)
• Gaps: 38/314 - (12%)

  Fly   308 IYENPSRVISMRATQSQRSESPIYSNTTASSATLAVVPQH--HHQGHL-----AVPSGSGGGSLS 365
            |...|..|  || .:|.|..:|.|     ...:||.||:.  ..|..|     ||.:|..|....
Mouse    79 IQRTPHEV--MR-RESHRLSAPSY-----LVRSLADVPRECGSSQSFLTEVNFAVENGDSGSRYF 135

  Fly   366 GSGRGGSSGSVRGASTSVQSLY--------VPPRTPPSA---VAGAGGSANGSLQKVPSQQSLTE 419
            .|.........|......|..|        :..|.|.|.   .:|.|.....||..:.:..|
Mouse   136 FSDNFFDGQRRRPLGDRAQEDYRYYEYNHDLFQRMPQSQGRHTSGIGRVTATSLGNLTNHGS--- 197

  Fly   420 PEELPLPPGWATQYTLHGRKYYIDHNAHTTHWNHPLEREGLPVGWRRVVSKMHGTYYENQYTGQS 484
             |:|||||||:..:|:.|||||||||.:||||:|||||||||.||.||.|...||||.:....::
Mouse   198 -EDLPLPPGWSVDWTMRGRKYYIDHNTNTTHWSHPLEREGLPPGWERVESSEFGTYYVDHTNKRA 261

  Fly   485 QRQHPCLTSYYVYTTSAEPPKAIRPEASLYAPPTHTHNALVPANPYLLEEIPKWLAVYSEADSSK 549
            |.:|||..|...|  ...||...:|:.:     ....:.|||||||...|||.||.||:.|....
Mouse   262 QYRHPCAPSVPRY--DQPPPITYQPQQT-----ERNQSLLVPANPYHTAEIPDWLQVYARAPVKY 319

  Fly   550 DHLLQFNMFSLPELEGFDSMLVRLFKQELGTIVGFYERYRRALILE-KNRRAGQ 602
            ||:|::.:|.|.:|:.:..||..||.:||..||..||.||:||:.| :||:..|
Mouse   320 DHILKWELFQLADLDTYQGMLKLLFMKELEQIVKLYEAYRQALLTELENRKQRQ 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sav	NP_788721.1	PAT1	<95..>225	CDD:401645
		WW	425..454	CDD:459800	19/28 (68%)
		SARAH_Sav	533..599	CDD:439176	30/66 (45%)
Sav1	NP_071311.1	WW	203..233	CDD:238122	20/29 (69%)
		WW	238..267	CDD:238122	12/28 (43%)
		SARAH_Sav	303..369	CDD:439176	29/65 (45%)