DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sav and magi2a

DIOPT Version :9

Sequence 1:	NP_788721.1	Gene:	sav / 252554	FlyBaseID:	FBgn0053193	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	NP_001314782.1	Gene:	magi2a / 564112	ZFINID:	ZDB-GENE-050810-4	Length:	1503	Species:	Danio rerio

Alignment Length:	229	Identity:	52/229 - (22%)
Similarity:	84/229 - (36%)	Gaps:	61/229 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   299 GSYSSDSY----------PIYENPSRVISMRAT---QSQRSESPIYSNTTASSATLAVVPQHHHQ 350
            |:|..:.|          |:..|.:..:...||   |.:|..:...||...:    .:.|....:
Zfish   180 GTYEDNYYGTPKPPAEPSPLLLNVAEQLLPGATPTSQGKRRRNKSVSNMEKA----GIEPPEEEE 240

  Fly   351 GHLAVPSGSG-----------GGSLSGSGRGGSSGSVRGASTSVQSLYVPPRTPPSAVAGAGGSA 404
            ....|.:|:|           ..|...||...::.....::.:.:....||::||..
Zfish   241 EERPVINGNGVAITPESSEHEDKSTDASGEMATTCPSETSTDAPKEDTEPPKSPPKP-------- 297

  Fly   405 NGSLQKVPSQQSLTEPEEL-PLPPGWATQYTLHGRKYYIDHNAHTTHWNHP-----------LER 457
                         .|.:|| |||..|...||..|..|:||||..||.|..|           .:.
Zfish   298 -------------DENDELGPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKE 349

  Fly   458 EGLPVGWRRVVSKMHGTYYENQYTGQSQRQHPCL 491
            ..||.||.::...::||||.:....::|.::|.|
Zfish   350 NELPYGWEKIDDPIYGTYYVDHINRRTQFENPVL 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sav	NP_788721.1	WW	425..454	CDD:278809	14/28 (50%)
magi2a	NP_001314782.1	PDZ_signaling	25..100	CDD:238492
		NK	122..286	CDD:302627	18/109 (17%)
		WW	307..337	CDD:238122	14/29 (48%)
		WW	352..381	CDD:278809	9/28 (32%)
		PDZ	431..511	CDD:214570
		PDZ	595..676	CDD:214570
		PDZ	762..856	CDD:214570
		PDZ_signaling	920..1007	CDD:238492
		PDZ_signaling	1182..1262	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284488at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010