DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sav and magi3a

DIOPT Version :9

Sequence 1:	NP_788721.1	Gene:	sav / 252554	FlyBaseID:	FBgn0053193	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	NP_001352122.1	Gene:	magi3a / 561689	ZFINID:	ZDB-GENE-090312-48	Length:	1355	Species:	Danio rerio

Alignment Length:	148	Identity:	41/148 - (27%)
Similarity:	58/148 - (39%)	Gaps:	26/148 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   391 RTPPSAVAGAGGSANGSLQKVPSQQSLTEPEELPLPPGWATQYTLHGRKYYIDHNAHTTHWNHP- 454
            :|.||....:......:...:|...|     :.|||..|...||..|..|:||||:.||.|..|
Zfish   260 KTVPSYTQSSSSMDFRNWNTMPRDDS-----QDPLPKNWEMAYTETGMVYFIDHNSKTTTWLDPR 319

  Fly   455 ----------LEREGLPVGWRRVVSKMHGTYYENQYTGQSQRQHPCLTSYYVYTTSAEPPKAIRP 509
                      .|...||.||.::....:||||.:....::|.::|.          .|..|.:..
Zfish   320 LAKKAKPPEKCEDGELPYGWEKIEDPQYGTYYVDHINQKTQFENPV----------QEAKKKLSQ 374

  Fly   510 EASLYAPPTHTHNALVPA 527
            |.|....||...:|.|.|
Zfish   375 ETSPTNQPTAAASAAVAA 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sav	NP_788721.1	WW	425..454	CDD:278809	14/28 (50%)
magi3a	NP_001352122.1	PDZ_signaling	32..98	CDD:238492
		NK	120..>194	CDD:327404
		WW	288..320	CDD:197736	16/31 (52%)
		WW	335..364	CDD:306827	9/28 (32%)
		PDZ	421..502	CDD:214570
		PDZ	579..654	CDD:214570
		PDZ_signaling	734..818	CDD:238492
		PDZ_signaling	862..948	CDD:238492
		PDZ_signaling	1032..1105	CDD:238492
		MIP-T3	<1177..>1334	CDD:313469
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284488at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920