Protein Alignment sav and sav1

DIOPT Version :10

• Sequence 1: NP_788721.1
• Gene: sav / 252554
• FlyBaseID: FBgn0053193
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_001004560.1
• Gene: sav1 / 447821
• ZFINID: ZDB-GENE-040912-28
• Length: 397
• Species: Danio rerio
• Alignment Length: 602
• Identity: 145/602 - (24%)
• Similarity: 209/602 - (34%)
• Gaps: 231/602 - (38%)

  Fly    15 MLSR-RNKEKSQHKEGVVGKYMKKDTPPDISVINVWSDQRAKKKSLQRCASTSPSCEFHPRSSST 78
            |||| ::|.::.....|.|||:||:|.|.:
Zfish     1 MLSRKKSKNEASKPPEVQGKYVKKETSPLL----------------------------------- 30

  Fly    79 SRNTYSCTDSQPDYYHARRAQSQMPLQQHSHSHPHSLPHPSHPHVRSHPPLPPHQFRASSNQLSQ 143
             ||..                            |..:.||:  .:|..|||
Zfish    31 -RNLM----------------------------PSFIRHPT--FLRREPPL-------------- 50

  Fly   144 NSSNYVNFEQIERMRRQQSSPLLQTTSSPAPGAGGFQRSYSTTQRQHHPHLGGDSYDADQGLLSA 208
                      :|.:          :...|.||.|              |:..|...|     :|.
Zfish    51 ----------VEPV----------SAGVPGPGPG--------------PYTTGSVGD-----VSG 76

  Fly   209 SYANMLQLPQRPHSPAHYAVPPQQQQH-----PQIHQQHASTPFGSTLRFDRAAMSIRERQPRYQ 268
            ..:.:...|  |.:|...:   :::.|     |.:|:.::.:                  .|.|.
Zfish    77 PKSFLRNAP--PRTPLEVS---RRESHRLSAPPHLHRDYSPS------------------SPSYI 118

  Fly   269 PTSSPMQQQQQQQQQQQQQLQHTQLAAHLGGSYSSDSYPIYENPSRVISMRATQSQRSESPIYSN 333
            ..:|.:.:...                  .|.|.....|.|.|          |.:|:..|.:.|
Zfish   119 SDASSVTENGD------------------NGPYYYPPEPYYNN----------QPRRARRPDHFN 155

  Fly   334 TTASSATLAVVPQHHHQGHLAVPSGSGGGSLSGSGRGGSSGSVRGASTSVQSLYVPPRT------ 392
            ...         :::....|..|...|                            .|:|
Zfish   156 ENY---------RYYDHNELNFPRNPG----------------------------QPQTPQPHSR 183

  Fly   393 PPSAVAGAGGSANGSLQKVPSQQSLTEPEELPLPPGWATQYTLHGRKYYIDHNAHTTHWNHPLER 457
            ||.|:......:.|:|..:..       ||..|||||...:|:.||||:||||.:||||:|||||
Zfish   184 PPPAIGRVPAKSVGNLTTMSG-------EEAALPPGWTVDWTIRGRKYFIDHNTNTTHWSHPLER 241

  Fly   458 EGLPVGWRRVVSKMHGTYYENQYTGQSQRQHPCLTSYYVYTTSAEPPKAIRPEASLYAPPTHTHN 522
            ||||.||.||.|...|.||.:....::|.:|||..|...|.....||...:|.     ||.....
Zfish   242 EGLPPGWERVESAEFGVYYVDHINKRAQYRHPCAPSVPRYDQPPPPPVTYQPR-----PPERNPP 301

  Fly   523 ALVPANPYLLEEIPKWLAVYSEADSSKDHLLQFNMFSLPELEGFDSMLVRLFKQELGTIVGFYER 587
            .|||||||...|||.||.||:.|....||:|::.:|.|.:|:.:..||..||.:||..||..||.
Zfish   302 VLVPANPYHSAEIPDWLQVYARAPLKYDHILKWELFQLMDLDTYQGMLKLLFMKELECIVKSYEA 366

  Fly   588 YRRALILEKNRRAGQNQ 604
            ||:||:.|.:.|..:.|
Zfish   367 YRQALLTELDTRKQRQQ 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sav	NP_788721.1	PAT1	<95..>225	CDD:401645	19/129 (15%)
		WW	425..454	CDD:459800	18/28 (64%)
		SARAH_Sav	533..599	CDD:439176	29/65 (45%)
sav1	NP_001004560.1	WW	210..240	CDD:238122	19/29 (66%)
		WW	245..274	CDD:238122	11/28 (39%)
		SARAH_Sav	312..378	CDD:439176	29/65 (45%)