DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sav and Magi

DIOPT Version :9

Sequence 1:	NP_788721.1	Gene:	sav / 252554	FlyBaseID:	FBgn0053193	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	NP_001286661.1	Gene:	Magi / 37403	FlyBaseID:	FBgn0034590	Length:	1202	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	97/428 - (22%)
Similarity:	138/428 - (32%)	Gaps:	167/428 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 TTSSPAPGAGGFQRSYSTTQRQHHPHLGGDSYDADQGLLSASYANMLQLPQRPHSPAHYAVPPQQ 232
            |||:...|||...|..:|.:                                  ||..|.:..||
  Fly     8 TTSTAGGGAGVAARGVATAK----------------------------------SPTDYLMLQQQ 38

  Fly   233 QQHPQIHQQHASTPFGSTLRFDRAAMSIRERQPRYQPTSSPMQQQQQQQQ----QQQQQLQHTQL 293
            ||..|..|||.:                          |:...||||.||    ....|.||:..
  Fly    39 QQQQQQQQQHFN--------------------------SNHFYQQQQPQQLAPLNASHQHQHSHP 77

  Fly   294 AAHLGGSYSSDSYPIYENPSRVISMRATQSQR---------------SESPIYSNTTASSATLAV 343
            ..|.....::.|:..:...|.:.|..|..|.|               .|....|.|.:|:.|..|
  Fly    78 HPHPHPVAAATSFATFNGNSNLNSSLANGSSRKFNCSRDNVDDGGDAGEMAAASQTLSSAGTDVV 142

  Fly   344 VPQHHH-----------QGHLAVPSG-------------------------------SGGGSL-- 364
            .....|           .|.||.|.|                               ||..||
  Fly   143 GNGSGHGNGTVTGNGEKSGGLAPPGGHHLRPPPPPALKKSASAVIGNSASREDVASLSGTSSLNS 207

  Fly   365 -------------------------SGSGRGGSSGSV-RGASTS-VQSLYVPPRTPPSAVAGAGG 402
                                     :.:||||...|: :|:..: :|:.|....|..|::....|
  Fly   208 QMSVHNQFISGLPSNGIGSNGVHGGAATGRGGPPNSILKGSKENLLQNTYYNGETGDSSLGSECG 272

  Fly   403 SANGSLQKVPSQQSLTEPEE--LPLPPGWATQYTLHGRKYYIDHNAHTTHWNHP---------LE 456
            .  |.:|. .:.:|..:|.:  .||||.|.|.||..|..|:||||..|:||..|         ||
  Fly   273 V--GDVQH-QNHESHDDPGDGLGPLPPKWETAYTERGELYFIDHNTGTSHWLDPRLSKYQKKSLE 334

  Fly   457 ---REGLPVGWRRVVSKMHGTYYENQYTGQSQRQHPCL 491
               .:.||.||.::...|:|.|:.:....::|.::|.|
  Fly   335 DCCEDELPYGWEKIEDSMYGMYFIDHVNRRTQYENPVL 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sav	NP_788721.1	WW	425..454	CDD:278809	16/28 (57%)
Magi	NP_001286661.1	WW	294..323	CDD:278809	16/28 (57%)
		WW	342..372	CDD:238122	8/29 (28%)
		PDZ	443..534	CDD:214570
		DegQ	<455..534	CDD:223343
		PDZ_signaling	606..668	CDD:238492
		PDZ	925..1011	CDD:214570
		PDZ_signaling	1029..1110	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443413
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284488at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.940