DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sav and magi-1

DIOPT Version :9

Sequence 1:	NP_788721.1	Gene:	sav / 252554	FlyBaseID:	FBgn0053193	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	NP_001255577.1	Gene:	magi-1 / 178107	WormBaseID:	WBGene00010444	Length:	1054	Species:	Caenorhabditis elegans

Alignment Length:	337	Identity:	78/337 - (23%)
Similarity:	118/337 - (35%)	Gaps:	72/337 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   272 SPMQQQQQQQQQQQQQLQHTQLAAHL--GGSYSSDSYPIYENPSRVISMRATQSQRSESPIYSNT 334
            |.|.:.:..:..:....:|.|:|..:  .|:.:.|          :..:.|.:....|.......
Worm   133 SGMVRSEVNRILEDMMREHDQIAIEILPAGAITDD----------ICELLADRKSSGELQTIIRE 187

  Fly   335 TASSATLAVVPQHHHQG-----HLAVPSGSGGGSLSGSGRGGSSGSVRGASTSVQSLYVPPRTPP 394
            .....|:....:...:|     |....|......|..||....:|:.:|      .||..|| |.
Worm   188 NLYQKTVPYTTRPPREGEVDGEHYRFVSVDDFNKLLDSGDLLENGTYQG------HLYGTPR-PV 245

  Fly   395 SAVAGAGGSANGSLQKVPSQQSLTEPEELPLPPGWATQYTLHGRKYYIDHNAHTTHWNHPLEREG 459
            ...|.......||              |..|||.|.|.||.:|.||:||||..||.|:.|.|
Worm   246 ECYADDDMMLMGS--------------EGLLPPNWETAYTENGDKYFIDHNTGTTTWDDPRE--- 293

  Fly   460 LPVGWRRVVSKMHGTYYENQYTGQSQRQHPCLTSYYVYTTSAEPPKAIRPEASLYAPPTHTHNAL 524
            ||.||.:|..:.:||:|.:....::|.:.|    |....:||...:.:: ..:|.:...|.||
Worm   294 LPPGWEQVDDQNYGTFYVDHINRKTQYERP----YGFGGSSATIDQPVK-YGTLPSSTNHNHN-- 351

  Fly   525 VPANPYLLEEIPKWLAVYSEADSSKDHLLQFNMFSLPELEGFDSMLVRLFK----QELGTIVGFY 585
                           .:||..:|.     .....|.|...||||...|..|    .|..|....|
Worm   352 ---------------NIYSHYNSG-----TLKSSSSPRDSGFDSSPTRYRKFGDPPETATSSADY 396

  Fly   586 ERYRRALILEKN 597
            :.:.:......|
Worm   397 DHHSKMFSRSSN 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sav	NP_788721.1	WW	425..454	CDD:278809	17/28 (61%)
magi-1	NP_001255577.1	NK	180..>244	CDD:302627	14/70 (20%)
		WW	263..293	CDD:238122	17/29 (59%)
		WW	294..323	CDD:278809	9/28 (32%)
		PDZ	421..510	CDD:214570
		PDZ_signaling	535..600	CDD:238492
		PDZ_signaling	717..800	CDD:238492
		PDZ_signaling	822..902	CDD:238492
		PDZ_signaling	968..1049	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284488at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010