DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sav and Magi1

DIOPT Version :9

Sequence 1:	NP_788721.1	Gene:	sav / 252554	FlyBaseID:	FBgn0053193	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	XP_006505643.1	Gene:	Magi1 / 14924	MGIID:	1203522	Length:	1484	Species:	Mus musculus

Alignment Length:	286	Identity:	67/286 - (23%)
Similarity:	107/286 - (37%)	Gaps:	68/286 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   299 GSYSSDSYPIYENPSRVIS--------MRATQSQRSESPIYSNTTASSATLAVVPQHHHQGHLAV 355
            |:|..:.|...:.||:.:|        :.:.||...:|......:.:....|.:....::....|
Mouse   180 GTYEGNYYGTPKPPSQPVSGKVITTDALHSLQSGSKQSTPKRTKSYNDMQNAGIVHPENEEEEDV 244

  Fly   356 PSGSGGGSLSGSGRGGSSGSVRGASTSV--QSLYVPPRTPPSAVAGAGGSANGSLQKVPSQQSLT 418
            |..:  .|.:.........:::.|:...  .|:...|.|.||             ||.|....|:
Mouse   245 PEMN--SSFTADSGDQDEHTLQEATLPPVNSSILAAPITDPS-------------QKFPQYLPLS 294

  Fly   419 EPEEL-PLPPGWATQYTLHGRKYYIDHNAHTTHW---------NHPLE-----REG--------- 459
            ..:.| |||..|...||.:|..|:||||..||.|         ..|||     .||
Mouse   295 AEDNLGPLPENWEMAYTENGEVYFIDHNTKTTSWLDPRCLNKQQKPLEECEDDEEGVHTEELDSE 359

  Fly   460 --LPVGWRRVVSKMHGTYYENQYTGQSQRQHPCLTS----YYVYTTSAEPPKAIRPE------AS 512
              ||.||.::...::|.||.:....::|.::|.|.:    ........:.|:..:||      ||
Mouse   360 LELPAGWEKIEDPVYGVYYVDHINRKTQYENPVLEAKRKKQLEQQQQQQQPQPPQPEEWTEDHAS 424

  Fly   513 LYAP--PTHTHNALVPANPYLLEEIP 536
            :..|  |:|.     |:||....|.|
Mouse   425 VVPPVAPSHP-----PSNPEPARETP 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sav	NP_788721.1	WW	425..454	CDD:278809	14/37 (38%)
Magi1	XP_006505643.1	PDZ_signaling	15..100	CDD:238492
		GuKc	122..293	CDD:214504	22/127 (17%)
		WW	302..331	CDD:366073	14/28 (50%)
		WW	362..393	CDD:197736	9/30 (30%)
		PDZ	462..548	CDD:214570
		PDZ	633..716	CDD:214570
		MAGI_u5	715..798	CDD:374709
		PDZ_signaling	840..915	CDD:238492
		PDZ_signaling	989..1084	CDD:238492
		PDZ	1145..1227	CDD:214570
		PRK12678	1203..>1452	CDD:237171
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284488at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010