DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sav and magi1

DIOPT Version :9

Sequence 1:	NP_788721.1	Gene:	sav / 252554	FlyBaseID:	FBgn0053193	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	XP_031757087.1	Gene:	magi1 / 100379993	XenbaseID:	XB-GENE-940612	Length:	1468	Species:	Xenopus tropicalis

Alignment Length:	340	Identity:	78/340 - (22%)
Similarity:	118/340 - (34%)	Gaps:	83/340 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   292 QLAAHLGGSYSSDSYPIYENPSRVISMRATQS----QRSESPIYSNTTASSATLAVVPQHHHQGH 352
            ::..:.|..|.:...|......:|||..|.|:    .:..:|..:.:........||...|::..
Frog   173 EVGTYEGNYYGTPKPPSQPTSGKVISRDALQNPLAGSKQSTPKRTKSYNDMQNAGVVHTDHYEFD 237

  Fly   353 LAVPSGSGGGSLSGSGRGGSSGSVRGASTSVQSLYVPPRT---PPSAVAGAGGSANGSLQKVPSQ 414
            ...|      .:|.|..|.||.:........|. .|||..   |...:..|  |.|......|.:
Frog   238 DDAP------EMSSSFTGDSSEADEHTINLSQD-KVPPAARILPTFPITEA--SQNLPHYLPPDE 293

  Fly   415 QSLTEPEELPLPPGWATQYTLHGRKYYIDHNAHTTHW---------NHPLE-----REG------ 459
            :||.     |||..|...:|.:|..|:||||..||.|         ..|||     .||
Frog   294 ESLG-----PLPDNWEMAFTENGEVYFIDHNTKTTSWLDPRCLNKQQKPLEECEDDEEGVHTEEL 353

  Fly   460 ----------LPVGWRRVVSKMHGTYYENQYTGQSQRQHPCLTSYYVYTTSAEPPKAIRPEAS-- 512
                      ||.||.::...::|.||.:....::|.::|.|        .|:..|.:..:.|
Frog   354 DSELGIGSPELPAGWEKIEDPVYGVYYVDHINKKTQYENPVL--------EAKRKKQLGQQQSEE 410

  Fly   513 -------LYAPPTHTHNALVPANPYLLEEIPKWLAVYSEADSSKDHLLQFNMFSLPELEG-FDSM 569
                   :..||....|.|.|...             ..|..:..|:..|...:..||:| |...
Frog   411 WTGDHPTIAPPPIMLPNNLTPKKK-------------EPARETASHVKPFFTRNPSELKGKFIHT 462

  Fly   570 LVRLFKQELG-TIVG 583
            .:|...:..| |:||
Frog   463 KLRKSSRGFGFTVVG 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sav	NP_788721.1	WW	425..454	CDD:278809	13/37 (35%)
magi1	XP_031757087.1	NK	117..>232	CDD:418433	11/58 (19%)
		MAGI_u1	197..257	CDD:406950	14/65 (22%)
		WW	299..328	CDD:395320	13/28 (46%)
		WW	364..395	CDD:197736	9/30 (30%)
		PDZ	458..544	CDD:214570	6/20 (30%)
		PDZ	629..712	CDD:214570
		MAGI_u5	713..800	CDD:406953
		PDZ_signaling	800..883	CDD:238492
		PDZ_signaling	958..1053	CDD:238492
		PDZ	1111..1196	CDD:214570
		PTZ00121	<1221..>1446	CDD:173412
		U2AF_lg	1327..>1433	CDD:273727
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284488at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010