Protein Alignment DIP2 and Dip2c

DIOPT Version :9

• Sequence 1: NP_612019.2
• Gene: DIP2 / 252479
• FlyBaseID: FBgn0024806
• Length: 1773
• Species: Drosophila melanogaster
• Sequence 2: XP_038951677.1
• Gene: Dip2c / 307067
• RGDID: 1560155
• Length: 1626
• Species: Rattus norvegicus
• Alignment Length: 1826
• Identity: 959/1826 - (52%)
• Similarity: 1194/1826 - (65%)
• Gaps: 267/1826 - (14%)

  Fly     6 SLPGYVREKLAELDLELSEGDITQKGYEKKRAKLLQPFLKKPEGDKVKSTPPPPYYNVKNANNST 70
            :||..||.:||||:|||||||||||||||||:||:..:|           |.||..|
  Rat    10 ALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYL-----------PQPPTAN-------- 55

  Fly    71 NHGNINNDGVIV------SSEGYSYVTEVPSLSSSQQRHSKKIDFHQQAAMSLSSAPQSGNAGAP 129
                    |..|      ..||   |...|..|:    |....|..:.||.. .:|..:||  .|
  Rat    56 --------GAAVVRCRLQPGEG---VPRRPFRSA----HIGVCDIREAAARE-RAASAAGN--RP 102

  Fly   130 ------GYENMRPQGGAVGDPGYQNTREPSAFQNQQSTNNSQHRQRRTQRKVTHNEKRYHSEVRQ 188
                  |.:...|          |..|.|..    .|:.:..||:|.:..:    ::||.|:|..
  Rat   103 LFYFRFGVDQALP----------QERRAPVT----PSSASRYHRRRSSGSR----DERYRSDVHT 149

  Fly   189 EAVQQALAALKGRPKPSLPMPSKRTSVL-----------NRSPGCNDELDSSTDDESIPEETISP 242
            ||||.|||..|.| |.::||||||.|::           :.|.|..||.....|.:..|..:
  Rat   150 EAVQAALAKHKER-KMAVPMPSKRRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSS--- 210

  Fly   243 DKEYNYPRDH-ISNSILPPEPIIKPPIRESSMGS-QQHARTDV-KQNQITNQKYTAPNSAPERRP 304
              :.:...:| ||.:|..............|.|| ..|...|| .|..|.|      :|||
  Rat   211 --QGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHIEN------HSAP---- 263

  Fly   305 PQNLPPLPTSEPLSSDYPPIAYKRENDFSDKAFKQKQYNAPDITQFNNAH-----RAADRVT--- 361
                                                    ||:|.:.:.|     |.....|
  Rat   264 ----------------------------------------PDVTTYTSEHSIQVERPQGSTTSRT 288

  Fly   362 --RYVNVSQNELNETDANG---KWKVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDP 421
              :|.|.   ||.|| .:|   ..:||||||||:||||||||.||.||:.| |.|..:.....||
  Rat   289 APKYGNA---ELMET-GDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVD-DFEELLEVQQPDP 348

  Fly   422 NAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVTTTLTYGKLLS 486
            |.|||||:.|...:||||.:....|.:||.||||:||.|.|:|..|.:|.|||....||||||.:
  Rat   349 NQPKPEGAQMLATRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWT 413

  Fly   487 RAQKIAHALSTKIFSKGPEQVTLKPGDRVALVYPNNDPLSFITAWYGCMFRGLVPLPIELPLSSS 551
            |:.|:|:.:..|:.:|  ::..::||||||||:|||||.:|:.|:|||:...:||:|||:||:..
  Rat   414 RSMKVAYNILHKLGTK--QEPMVRPGDRVALVFPNNDPAAFMVAFYGCLLAEVVPVPIEVPLTRK 476

  Fly   552 DTPPQQVGFLLSSCGITVALTSEACLKGLPKSTTTGEIAKLKGWPRLQWFVTE--HLPKPPKEFN 614
            |...||:||||.|||:||||||:||.|||||| .||||.:.||||:|.|||||  ||.|||:::
  Rat   477 DAGSQQIGFLLGSCGVTVALTSDACHKGLPKS-PTGEIPQFKGWPKLLWFVTESKHLSKPPRDW- 539

  Fly   615 VGNLRADDSAAAYIEYTTDKEGSVMGVTVTRAAMINHCRALTMACHYTEGETIVCVLDFKREVGL 679
            ..:::..::..|||||.|.|:|||:||||||.|::.||:|||.||.|||.||||.|||||::|||
  Rat   540 FPHIKDANNDTAYIEYKTCKDGSVLGVTVTRIALLTHCQALTQACGYTEAETIVNVLDFKKDVGL 604

  Fly   680 WHSVLTSVLNGMHVIFIPYALMKLRPSSWMQLITKHRASCCLVKSRDLHWGLLATKDHKDISLSS 744
            ||.:||||:|.||||.|||||||:.|.||:|.:.:::|....|||||:||.|:|.:|.:|::|||
  Rat   605 WHGILTSVMNMMHVISIPYALMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHRDQRDVNLSS 669

  Fly   745 LRMLLVADGANPWSLSSCDQFLSVFQAKGLRSDAICPCASSSEVFTVSLRRPGRGSCGFSPSATG 809
            ||||:|||||||||:||||.||:|||:||||.:.|||||||.|..||::|||    ...|....|
  Rat   670 LRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRRP----TDDSNQPPG 730

  Fly   810 RGVLSMAALSHGVVRVDSEDSLTSLTLQDCGQVMPAAQMVVVRSEGPPVLCKTDQVGEICVTSGS 874
            ||||||..|::||:|||||:.|:.||:||.|.|||.|.|..|:.:|.|.||:||::||:||.:.:
  Rat   731 RGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGVPQLCRTDEIGELCVCAVA 795

  Fly   875 TSASYFGLDGMTNSTFKVQPLLEELEQPKDGNGTVNIISKPIGEDFYVRSGLLGFLGPGGLVFVC 939
            |..||:||.|||.:||:|.|:...              ..||.|..::|:|||||:||||||||.
  Rat   796 TGTSYYGLSGMTKNTFEVFPMTSS--------------GAPISEYPFIRTGLLGFVGPGGLVFVV 846

  Fly   940 GSRDGLMTVTGRKHNADDIIATVLAVEPMRFIYRGRIAVFSIKVLRDERVCVIAEQRPDCSEEES 1004
            |..||||.|:||:||||||:||.||||||:|:|||||||||:.||.|||:.::||||||.:||:|
  Rat   847 GKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERIVIVAEQRPDSTEEDS 911

  Fly  1005 FQWMSRVLQAVDSIHQVGIYCLALVPPNHLPKTPLGGIHLCEARRRFLEGSLHPANVLMCPHTCV 1069
            ||||||||||:|||||||:|||||||.|.|||||||||||.|.::.||||||||.||||||||||
  Rat   912 FQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPHTCV 976

  Fly  1070 TNLPKPRELHQGVQTAAKLSSSSGCGITDTGVGPASVMVGNLVQGNRLAEAHGRDVGLAEDCERK 1134
            |||||||:                   ....:|||||||||||.|.|:|:|.|||:|..||.::.
  Rat   977 TNLPKPRQ-------------------KQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQA 1022

  Fly  1135 PQL------ITGVLRWRANTSPDHIIFTLLNSKGAIAKTLTCSELHKRAEKIAALLQERGRIEPG 1193
            .::      ::.||:|||.|:|||:::||||.:|.||.:|||.:|||||||||.:|.|||.::.|
  Rat  1023 RKVRTEFLFLSEVLQWRAQTTPDHLLYTLLNCRGTIANSLTCVQLHKRAEKIAVMLMERGHLQDG 1087

  Fly  1194 DHVALIFPPGLDLLCAFYGCLYLGAIPITIRPPHPQNLNTTLPTVRMIVDVSKSGIVLSIQPIIK 1258
            |||||::|||:||:.|||||||.|.:|||:|||||||:.||||||:|||:||:|..:::.|.|.|
  Rat  1088 DHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICK 1152

  Fly  1259 LLKSREAATSIDPKTWPPILDIDDNPKRKYAGIATVSF-DSSAYLDFSVSTCGRLSGVNITHRSL 1322
            ||:|||||.::|.:|||.|||.||.||::.|.|...|. |:.|||||||||.|.|:||.::|.:.
  Rat  1153 LLRSREAAAAVDVRTWPLILDTDDLPKKRPAQIYKPSNPDTLAYLDFSVSTTGMLAGVKMSHAAT 1217

  Fly  1323 SSLCASLKLACELYPSRHVALCLDPYCGLGFVMWTLIGVYSGHHSILIAPYEVEANPSLWLSTLS 1387
            |:.|.|:||.|||||||.||:|||||||||||:|.|..|||||.||||.|.|:|.||:|||..:|
  Rat  1218 SAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVS 1282

  Fly  1388 QHRVRDTFCSYGVIELCTKALSNSIPSLKQRNIDLRCVRTCVVVAEERPRVQLTQQFCKLFQALG 1452
            |::||||||||.|:|||||.|.:...|||.|.:||..|||||||||||||:.|||.|.|||:.||
  Rat  1283 QYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLG 1347

  Fly  1453 LNTRCVSTSFGCRVNPAICV----------QGASSAESAQVYVDMRALRNNRVALVERGAPNSLC 1507
            |:.|.||||||||||.|||:          ||.|..:...|||||||||::||.|||||:|:||.
  Rat  1348 LHPRAVSTSFGCRVNLAICLQPHRLWTLAEQGTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLP 1412

  Fly  1508 VIESGKLLPGVKVIIANPETKGHCGDSHLGEIWVQAPHNANGYFTIYGDETDYNDHFNAKLVTGA 1572
            ::||||:||||::|||||||||..||||||||||.:.|||:|||||||||:..:||||::|..|.
  Rat  1413 LMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGD 1477

  Fly  1573 TSELYARTGYLGFLRRTECSQSASLLDETTPSVASRDSDTESLNSISQLQLNFSNVSLGGNSEHS 1637
            |..::|||||||||||||
  Rat  1478 TQTIWARTGYLGFLRRTE----------------------------------------------- 1495

  Fly  1638 LVGGASNANDQELHDAVYVVGAVDEVISLRGMNYHPIDIENSVMRCHKKIAECAVFTWTNLLVVV 1702
                .::||. |.|||:|||||:||.:.||||.|||||||.||:|.||.:.||||||||||||||
  Rat  1496 ----LTDANG-ERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVV 1555

  Fly  1703 VELDGNESEALDLVPLVTNTVLEDHQLIVGVVVVVDPGVVPINSRGEKQRMHLRDGFLADQLDPI 1767
            |||||:|.|||||||||||.|||:|.||||||||||.||:|||||||||||||||||||||||||
  Rat  1556 VELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPI 1620

  Fly  1768 YVAYNM 1773
            ||||||
  Rat  1621 YVAYNM 1626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP2	NP_612019.2	DMAP_binding	3..115	CDD:283995	42/114 (37%)
		ARG80	33..369	CDD:227400	86/371 (23%)
		PRK09192	470..1061	CDD:236403	356/592 (60%)
		Dip2	470..1054	CDD:213273	350/585 (60%)
		AMP-binding	1142..1587	CDD:278902	291/455 (64%)
		AFD_class_I	1159..1762	CDD:302604	379/613 (62%)
Dip2c	XP_038951677.1	DMAP_binding	8..174	CDD:368923	76/219 (35%)
		Dip2	392..968	CDD:341231	357/597 (60%)
		Dip2	1048..1622	CDD:341231	389/625 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334835
Domainoid	1	1.000	611	1.000	Domainoid score	I180
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40996
Inparanoid	1	1.050	1706	1.000	Inparanoid score	I69
OMA	1	1.010	-	-		QHG52530
OrthoDB	1	1.010	-	-		D539697at2759
OrthoFinder	1	1.000	-	-		FOG0001187
OrthoInspector	1	1.000	-	-		otm46214
orthoMCL	1	0.900	-	-		OOG6_101035
Panther	1	1.100	-	-	LDO	PTHR22754
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1019
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770