Protein Alignment DIP2 and dip2b

DIOPT Version :9

• Sequence 1: NP_612019.2
• Gene: DIP2 / 252479
• FlyBaseID: FBgn0024806
• Length: 1773
• Species: Drosophila melanogaster
• Sequence 2: XP_002933754.2
• Gene: dip2b / 100487550
• XenbaseID: XB-GENE-1011309
• Length: 1579
• Species: Xenopus tropicalis
• Alignment Length: 1813
• Identity: 901/1813 - (49%)
• Similarity: 1140/1813 - (62%)
• Gaps: 286/1813 - (15%)

  Fly     5 ASLPGYVREKLAELDLELSEGDITQKGYEKKRAKLLQPFLKKPEGDKVKSTPPPPYYNVKNANNS 69
            ::||..|||:||||:|||||||||||||||||||||.|::.:.:|       ..|....:|.|.:
 Frog     9 SALPKEVREQLAELELELSEGDITQKGYEKKRAKLLGPYIPQTQG-------VDPALQKENRNQT 66

  Fly    70 TNHGNINNDGVIVSSEGYSYVTEVPSLSSSQQRHSKKIDFHQQAAMSLSSAPQSGNAGAPGYENM 134
            |..                  ...|:.|||:...::
 Frog    67 TGS------------------PAAPAQSSSKYHRAR----------------------------- 84

  Fly   135 RPQGGAVGDPGYQNTREPSAFQNQQSTNNSQHRQRRTQRKVTHNEKRYHSEVRQEAVQQALAALK 199
              .|||                                     .::||.|::..||||.|||..|
 Frog    85 --SGGA-------------------------------------RDERYRSDIHTEAVQAALAKHK 110

  Fly   200 GRPKPSLPMPSKRTSVLNRSPGCNDELDSSTDDESIPEETISPDKEYNYPRDH------ISNSIL 258
             ..|.:||||:||.|...:||.          |...|.:|.|..::....|..      ::.|:.
 Frog   111 -EQKMALPMPTKRRSTFVQSPA----------DACTPPDTSSASEDEGSLRRQAALSAALAQSLQ 164

  Fly   259 PPEPIIKPPIRESSMGSQ-----QHAR--------TDVKQN----------QITNQKYTAPNSAP 300
            ..|..|...::.||..|.     .|..        .|:..|          .:||    ..||..
 Frog   165 NSEAWINRSVQGSSTSSSASSTLSHGEVKSTSGTLADILSNTHIDSSPAPPDVTN----TTNSTT 225

  Fly   301 ERRPPQNLPPLPTSEPLSSDYPPIAYKRENDFSDKAFKQKQYNAPDITQFNNAHRAADRVTRYVN 365
            ......:...|.:..|.:.|.||....:                       ..|:||.|
 Frog   226 TTSTSSSSSSLSSVRPATIDLPPAGLVK-----------------------GVHKAARR------ 261

  Fly   366 VSQNELNETDANG---KWKVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPE 427
               :.|.:| |:|   ..:||.||||||||||||||.||.||:.| |.|..:.....|||.||||
 Frog   262 ---SSLMDT-ADGVAVNSRVSTKIQQLLNTLKRPKRPPLKEFFVD-DFEEIVEVPRPDPNQPKPE 321

  Fly   428 GSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVTTTLTYGKLLSRAQKIA 492
            |..:|||:||.|.:....|.::|.||||:||...|....|.||..||.|.|||||||.:|:.::|
 Frog   322 GRQVTPVKGEPLGVVCNWPPSVEAALQRWGTTQAKCSCLTALDVTGKPTYTLTYGKLWTRSVRLA 386

  Fly   493 HALSTKIFSKGPEQVTLKPGDRVALVYPNNDPLSFITAWYGCMFRGLVPLPIELPLSSSDTPPQQ 557
            :.|..|:.:|. ||| ||||||||||||||||:.|:.|:|||:...::|:|||:||:..|....|
 Frog   387 YTLLNKLGTKN-EQV-LKPGDRVALVYPNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGHQ 449

  Fly   558 VGFLLSSCGITVALTSEACLKGLPKSTTTGEIAKLKGWPRLQWFVTE--HLPKPPKEF-----NV 615
            :||||.|||:.:|||:|.||||||| |..|||.:.||||:|:|.||:  :|.|.||::     |.
 Frog   450 IGFLLGSCGVKIALTTEVCLKGLPK-TQNGEIVQFKGWPKLKWVVTDSRYLSKSPKDWQPHITNA 513

  Fly   616 GNLRADDSAAAYIEYTTDKEGSVMGVTVTRAAMINHCRALTMACHYTEGETIVCVLDFKREVGLW 680
            |      :..|||||.|.||||||||||:|.||::||:||:.||:||||||:|.||||||:.|||
 Frog   514 G------TEPAYIEYKTSKEGSVMGVTVSRIAMLSHCQALSQACNYTEGETLVNVLDFKRDAGLW 572

  Fly   681 HSVLTSVLNGMHVIFIPYALMKLRPSSWMQLITKHRASCCLVKSRDLHWGLLATKDHKDISLSSL 745
            |.:||:|:|.||.|.:|||:||..|.||:|.:...:....:||.|||||.::|.::.|||||:||
 Frog   573 HGILTNVVNKMHTISVPYAVMKACPLSWVQRVHASKGRVAVVKCRDLHWAMIAHREQKDISLASL 637

  Fly   746 RMLLVADGANPWSLSSCDQFLSVFQAKGLRSDAICPCASSSEVFTVSLRRPGRGSCGFSPSA--T 808
            |||:|.|||||||:||||.|||:||..||:.:.|||||:|.|..||::||||      .|.|  .
 Frog   638 RMLIVTDGANPWSVSSCDAFLSLFQNHGLKPEVICPCATSPEAMTVAIRRPG------VPGAPLP 696

  Fly   809 GRGVLSMAALSHGVVRVDSEDSLTSLTLQDCGQVMPAAQMVVVRSEGPPVLCKTDQVGEICVTSG 873
            ||.:|||..||:||:||::||..::||:||.|.|||.:.|..|:.||.|.|||||::|||||:..
 Frog   697 GRAILSMNGLSYGVIRVNTEDKNSALTVQDVGHVMPGSVMCTVKPEGVPQLCKTDEIGEICVSCK 761

  Fly   874 STSASYFGLDGMTNSTFKVQPLLEELEQPKDGNGTVNIISKPIGEDFYVRSGLLGFLGPGGLVFV 938
            .....|:||.|:|.:||:|.|              ||.....|||..::|:|||||:|||.||||
 Frog   762 GGGTMYYGLAGLTKNTFEVLP--------------VNASGASIGEIPFIRTGLLGFVGPGSLVFV 812

  Fly   939 CGSRDGLMTVTGRKHNADDIIATVLAVEPMRFIYRGRIAVFSIKVLRDERVCVIAEQRPDCSEEE 1003
            .|..||.:.|:||:||||||:||.||||..:.:|||||||||:.|..|||:.|:||||||.|||:
 Frog   813 VGKMDGTVMVSGRRHNADDIVATALAVESFKTLYRGRIAVFSVTVFYDERIVVVAEQRPDASEED 877

  Fly  1004 SFQWMSRVLQAVDSIHQVGIYCLALVPPNHLPKTPLGGIHLCEARRRFLEGSLHPANVLMCPHTC 1068
            |||||||||||:|||||||:|||||||.|.||||||||||:.:.::.||||||||.|:|||||||
 Frog   878 SFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHISQTKQLFLEGSLHPCNILMCPHTC 942

  Fly  1069 VTNLPKPRELHQGVQTAAKLSSSSGCGITDTGVGPASVMVGNLVQGNRLAEAHGRDVGLAE--DC 1131
            ||||||||:                   ...|||||||||||||.|.|:|:|.|||:|..|  |.
 Frog   943 VTNLPKPRQ-------------------KQPGVGPASVMVGNLVAGKRIAQASGRDLGQIEENDL 988

  Fly  1132 ERKPQLITGVLRWRANTSPDHIIFTLLNSKGAIAKTLTCSELHKRAEKIAALLQERGRIEPGDHV 1196
            .:|.|.:|.||:|||.|:|:|::|.|||:||......:|.:||||||:|||.|.::|.:..||:|
 Frog   989 VKKHQYLTEVLQWRAQTTPEHVLFILLNAKGTAVCNASCLQLHKRAERIAAALCDKGHLNAGDNV 1053

  Fly  1197 ALIFPPGLDLLCAFYGCLYLGAIPITIRPPHPQNLNTTLPTVRMIVDVSKSGIVLSIQPIIKLLK 1261
            .|:||||::|:.|||||||.|.||:|:||||.|||..|||||||||||||:..:|:.|.:::|||
 Frog  1054 VLLFPPGIELIAAFYGCLYAGCIPVTVRPPHAQNLAATLPTVRMIVDVSKAACILTTQALLRLLK 1118

  Fly  1262 SREAATSIDPKTWPPILDIDDNPKRKYAGI-ATVSFDSSAYLDFSVSTCGRLSGVNITHRSLSSL 1325
            |:|||.::|.||||.|:|.||.|:::...: ...:.:..|||||||||.|.|:||.::|.|:::|
 Frog  1119 SKEAAAAVDVKTWPTIIDTDDLPRKRVPQLYKPPTPEMLAYLDFSVSTTGMLTGVKMSHGSVNAL 1183

  Fly  1326 CASLKLACELYPSRHVALCLDPYCGLGFVMWTLIGVYSGHHSILIAPYEVEANPSLWLSTLSQHR 1390
            |.|:||.||||.:|.:|:|||||||||||:|.|..|||||.||||.|.|:|:|..||||.:||::
 Frog  1184 CRSIKLQCELYSTRQIAICLDPYCGLGFVLWCLCSVYSGHQSILIPPMELESNLFLWLSAVSQYK 1248

  Fly  1391 VRDTFCSYGVIELCTKALSNSIPSLKQRNIDLRCVRTCVVVAEERPRVQLTQQFCKLFQALGLNT 1455
            :|||||||.|:|:|:|.|.|.|..||.:.|:|..||||||||||||||.|...|.|||:.|||:.
 Frog  1249 IRDTFCSYSVMEMCSKGLGNQIEVLKTKGINLSYVRTCVVVAEERPRVALAYSFSKLFKDLGLSP 1313

  Fly  1456 RCVSTSFGCRVNPAICVQGASSAESAQVYVDMRALRNNRVALVERGAPNSLCVIESGKLLPGVKV 1520
            |.|||:||.|||.|||:||.|..:...||||:::||::||.|||||:|.||.::||||:||||.|
 Frog  1314 RAVSTTFGSRVNTAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERGSPQSLLLLESGKILPGVTV 1378

  Fly  1521 IIANPETKGHCGDSHLGEIWVQAPHNANGYFTIYGDETDYNDHFNAKLVTGATSELYARTGYLGF 1585
            ||.||||||..||||||||||.:.|.|:||:|||..||...||||.:|..|.|..|:|:||||||
 Frog  1379 IIVNPETKGPLGDSHLGEIWVNSAHTASGYYTIYDSETLQADHFNTRLSFGDTQTLWAKTGYLGF 1443

  Fly  1586 LRRTECSQSASLLDETTPSVASRDSDTESLNSISQLQLNFSNVSLGGNSEHSLVGGASNANDQEL 1650
            :||||                                                   .::||. |.
 Frog  1444 VRRTE---------------------------------------------------LTDANG-ER 1456

  Fly  1651 HDAVYVVGAVDEVISLRGMNYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGNESEALDL 1715
            |||::||||:||.:.|||:.|||||||.||.|.|:.|||||||||||||||||||.|:|.|||||
 Frog  1457 HDALFVVGALDETLELRGLRYHPIDIETSVSRIHRSIAECAVFTWTNLLVVVVELCGSEQEALDL 1521

  Fly  1716 VPLVTNTVLEDHQLIVGVVVVVDPGVVPINSRGEKQRMHLRDGFLADQLDPIYVAYNM 1773
            ||||||.|||:|.|||||||||||||:|||||||||||||||.|||||||||||||||
 Frog  1522 VPLVTNVVLEEHYLIVGVVVVVDPGVIPINSRGEKQRMHLRDSFLADQLDPIYVAYNM 1579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP2	NP_612019.2	DMAP_binding	3..115	CDD:283995	40/109 (37%)
		ARG80	33..369	CDD:227400	69/364 (19%)
		PRK09192	470..1061	CDD:236403	342/599 (57%)
		Dip2	470..1054	CDD:213273	336/592 (57%)
		AMP-binding	1142..1587	CDD:278902	264/445 (59%)
		AFD_class_I	1159..1762	CDD:302604	350/603 (58%)
dip2b	XP_002933754.2	DMAP_binding	8..126	CDD:368923	62/210 (30%)
		Dip2	359..935	CDD:341231	344/604 (57%)
		Dip2	1011..1575	CDD:341231	360/615 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	613	1.000	Domainoid score	I186
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1697	1.000	Inparanoid score	I71
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D539697at2759
OrthoFinder	1	1.000	-	-		FOG0001187
OrthoInspector	1	1.000	-	-		otm49297
Panther	1	1.100	-	-	O	PTHR22754
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1757
SonicParanoid	1	1.000	-	-		X1019
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.190