DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tyro3 and dpr9

DIOPT Version :9

Sequence 1:	NP_058788.1	Gene:	Tyro3 / 25232	RGDID:	3923	Length:	880	Species:	Rattus norvegicus
Sequence 2:	NP_001287332.1	Gene:	dpr9 / 2768670	FlyBaseID:	FBgn0038282	Length:	602	Species:	Drosophila melanogaster

Alignment Length:	334	Identity:	78/334 - (23%)
Similarity:	124/334 - (37%)	Gaps:	80/334 - (23%)

- Green bases have known domain annotations that are detailed below.

  Rat    42 MTVSQGQPVKLNCSVEGMDDP------------DIHWMKDGAVVQNASQVSISISE---QNWIGL 91
            :|...|:...|||.|:.:.:.            |||.:..|.....:.|...:|.:   ::|  :
  Fly   266 VTALLGKTAYLNCRVKNLGNKTMLLQVSWVRHRDIHLLTVGRYTYTSDQRFRAIHQPQTEDW--M 328

  Rat    92 LSLKSAERSDAGLYWCQVKDGEETKISQSVWLTVEGVPFFTVEPK-------DLAVPPNVPFQLS 149
            |.:|..:..|:|:|.|||  .....:|..:.|.|       |||.       ||.:.......|:
  Fly   329 LQIKYPQHRDSGIYECQV--STTPHMSHYIHLNV-------VEPSTEIIGAPDLYIESGSTINLT 384

  Rat   150 CEAVGPPEPVTIFWWRGPTKVGGPASSPSVLN-------VTGVTQRTEFSCEAHNIKGLATSRPA 207
            |.....|||....:|......   .|.|.::|       |:.||.:.:.:.....||....|...
  Fly   385 CIIQNSPEPPAYIFWNHNNAF---PSHPQIINYDSPRGGVSVVTNKGDTTTSFLLIKSARPSDSG 446

  Rat   208 IIRLQAPPAAPFNITVTTISSSNASVA-WVPGADGLALLHSCTVQVAHAPGEWEALAVVVPVPPF 271
            ..:.....|.|.::||..::..:.||: .||.::. |...|.:..:||      :|:|.|||
  Fly   447 HYQCNPSNAKPKSVTVHVLNGVSHSVSRGVPSSNA-ARGTSASSPLAH------SLSVCVPV--- 501

  Rat   272 TCLLRNL------------APATNYSLRVRCANALGPSPYGDWVPFQTKGLAPARAPQNFHAIRT 324
             |:|..|            |.||...|| ....|.|..|       .:.|.||...... |.:.:
  Fly   502 -CVLLQLGACRWIAALLGAALATPPPLR-STRRATGERP-------GSPGCAPIACDMR-HFLAS 556

  Rat   325 DSGLILEWE 333
                :|.|:
  Fly   557 ----VLRWQ 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tyro3	NP_058788.1	IG_like	39..125	CDD:214653	23/97 (24%)
		IGc2	46..111	CDD:197706	20/79 (25%)
		Ig2_Tyro3_like	131..209	CDD:143226	20/91 (22%)
		IG_like	135..204	CDD:214653	17/82 (21%)
		FN3	215..307	CDD:238020	28/104 (27%)
		fn3	315..396	CDD:278470	3/19 (16%)
		PTKc_Tyro3	498..781	CDD:270659
		Pkinase_Tyr	508..776	CDD:285015
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	804..827
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	842..864
dpr9	NP_001287332.1	Ig	263..361	CDD:299845	24/105 (23%)
		IG_like	263..360	CDD:214653	23/97 (24%)
		IG_like	371..464	CDD:214653	21/95 (22%)
		IGc2	377..456	CDD:197706	15/81 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910