Protein Alignment Ccnb1 and CycA

DIOPT Version :9

• Sequence 1: NP_741988.1
• Gene: Ccnb1 / 25203
• RGDID: 2291
• Length: 423
• Species: Rattus norvegicus
• Sequence 2: NP_524030.2
• Gene: CycA / 39340
• FlyBaseID: FBgn0000404
• Length: 491
• Species: Drosophila melanogaster
• Alignment Length: 467
• Identity: 119/467 - (25%)
• Similarity: 202/467 - (43%)
• Gaps: 103/467 - (22%)

  Rat    12 NTENKAKVSMAGAK--RVPVAVAASKPLLRSRTALGDIGNKVSEQSRIPLKKETKKLGSGTVTVK 74
            |.||......||.|  :.|:||               ||.|..:.:..|........|:..|
  Fly    12 NKENPGIKIPAGVKNTKQPLAV---------------IGGKAEKNALAPRANFAVLNGNNNV--- 58

  Rat    75 ALPKPVDKVPVCEPEVELDEPEPEPVMEVKHSPEPILVDTPSPSPMETSG---CAPA-------- 128
              |:|..||.|......|:..|.......|.:..|::....:.|..|.:.   .||:
  Fly    59 --PRPAGKVQVFRDVRNLNVDENVEYGAKKSNVVPVVEQFKTFSVYEDNNDTQVAPSGKSLASLV 121

  Rat   129 -------------EEYLCQAFSDVILAVSDVDADDGGDPNLCS---------------------- 158
                         :|.:........::|:||.:....|.::..
  Fly   122 DKENHDVKFGAGQKELVDYDLDSTPMSVTDVQSPMSVDRSILGVIQSSDISVGTETGVSPTGRVK 186

  Rat   159 ---------------EYVKDIYAYLRQLEEEQSVRPKYL-LGREVTGNMRAILIDWLIQVQMKFR 207
                           :|..||..|.|:.|::...:|.|: ..::::.|||:||||||::|..:::
  Fly   187 ELPPRNDRQRFLEVVQYQMDILEYFRESEKKHRPKPLYMRRQKDISHNMRSILIDWLVEVSEEYK 251

  Rat   208 LLQETMYMTVSIIDRFMQDSCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTYTKHQI 272
            |..||:|::|..:|||:....|.:..|||||..||:||:||||:||||:|:|.|:|:::|||.|:
  Fly   252 LDTETLYLSVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQV 316

  Rat   273 RQMEMKILRVLNFSLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELSMLDYD-MVHFAPSQIAA 336
            .:||..||::|:|.|..|....|:...:.:.::..:...:..|:.|||:::.: .:.:.||.:::
  Fly   317 LRMEQVILKILSFDLCTPTAYVFINTYAVLCDMPEKLKYMTLYISELSLMEGETYLQYLPSLMSS 381

  Rat   337 GAFCLALKILDNGEWTPTLQHYLSHTEESLLPVMQHLAKNIVMVNRGLTKHMTIK--------NK 393
            .:..||..||....|||.|:...::..|.|..|:.||...          |.|.|        .|
  Fly   382 ASVALARHILGMEMWTPRLEEITTYKLEDLKTVVLHLCHT----------HKTAKELNTQAMREK 436

  Rat   394 YATSKHAKISTL 405
            |....:.|::.:
  Fly   437 YNRDTYKKVAMM 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ccnb1	NP_741988.1	Interaction with CDK2. /evidence=ECO:0000250	159..167		3/7 (43%)
		Cyclin_N	163..288	CDD:278560	57/125 (46%)
		Interaction with CDK2. /evidence=ECO:0000250	248..251		2/2 (100%)
		Cyclin_C	290..408	CDD:281044	27/125 (22%)
CycA	NP_524030.2	Cyclin_N	206..332	CDD:278560	57/125 (46%)
		Cyclin_C	334..450	CDD:281044	27/125 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339988
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	1	1.000	-	-		FOG0000121
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100199
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X94
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750