DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jheh1 and Ephx3

DIOPT Version :9

Sequence 1:	NP_611385.1	Gene:	Jheh1 / 251984	FlyBaseID:	FBgn0010053	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_001028335.1	Gene:	Ephx3 / 71932	MGIID:	1919182	Length:	424	Species:	Mus musculus

Alignment Length:	138	Identity:	33/138 - (23%)
Similarity:	52/138 - (37%)	Gaps:	47/138 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 GLRTHFLHLMVYDDNKVGKKHYPVLL-LHGWPGS-------VREFYDFIHLLHQTNLDNNNKYIF 193
            |||.|::        ..|..:.|::| |||:|.:       :|||....|
Mouse   148 GLRLHYV--------SAGHGNGPLMLFLHGFPENWFSWRYQLREFQSHFH--------------- 189

  Fly   194 NVVVPSLPGYGWSQGTSRKGLGPAQVAVM--------MRNLMLRLGYNKFFIQGGDWGSIIGSNI 250
             ||...:.||..|.       .|.:|...        :::.:|.|||:|..:...|||:.:....
Mouse   190 -VVAVDMRGYSPSD-------APKEVDCYTIDLLLDDIKDTILGLGYSKCILVSHDWGASLAWEF 246

  Fly   251 ATLYPENV 258
            :..||..|
Mouse   247 SIYYPSLV 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jheh1	NP_611385.1	EHN	64..168	CDD:283978	10/31 (32%)
		MhpC	159..465	CDD:223669	28/116 (24%)
		Abhydrolase_5	159..>255	CDD:289465	25/111 (23%)
Ephx3	NP_001028335.1	Abhydrolase	139..>262	CDD:304388	33/138 (24%)
		MhpC	144..415	CDD:223669	33/138 (24%)
		Abhydrolase	<341..424	CDD:304388
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2361
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030