Protein Alignment Jheh1 and C45B11.6

DIOPT Version :9

• Sequence 1: NP_611385.1
• Gene: Jheh1 / 251984
• FlyBaseID: FBgn0010053
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001122878.1
• Gene: C45B11.6 / 6418708
• WormBaseID: WBGene00045379
• Length: 457
• Species: Caenorhabditis elegans
• Alignment Length: 520
• Identity: 126/520 - (24%)
• Similarity: 215/520 - (41%)
• Gaps: 139/520 - (26%)

  Fly     3 VTVKILVLILAIAGGLVYRNVTQLWADLPAPKLDPQEWWGDEAQPKDYEAYLKNNSEVIGNRLSY 67
            |.:.|..::|:|   .:::      .|.|..::||.::|..:...||       :..:....:..
 Worm    10 VVISIFSILLSI---YIHK------PDFPPLEIDPDDYWKLDDPEKD-------DDTIYSFTIDI 58

  Fly    68 PDKTIADLKERLNRTLRLTPPLEGVAFEYGFNTNYLKEVVEYWRDDYLP---------RWREREV 123
            .:..:::.||:| .:.|..|.|        ::|||         |:||.         .|::.:.
 Worm    59 KESEVSNFKEKL-ESERFLPTL--------YDTNY---------DNYLNELKQVLLGFNWKQHQH 105

  Fly   124 FLWQFNHFTTDIQGLRTHFLHLMVYDDNKVGKKHYPVLLLHGWPGSVREFYDFIHLL-----HQT 183
            ||..|..:.|:|:||:.|||.:.....:|..:. .|:|:.||:|||..:|:..|.:|     |..
 Worm   106 FLNTFKQYKTEIEGLKIHFLRVSTPPKDKKSRV-VPLLIFHGFPGSFWDFFKIIPILTNPSRHGF 169

  Fly   184 NLDNNNKYIFNVVVPSLPGYGWSQGTSRKGLGPAQVAVMMRNLMLRLGYNKFFIQGGD-WGSIIG 247
            :........|.|:||||||:.:|...:::|......|.::..||.||..|.:|:.|.: :||.:.
 Worm   170 DFGVEEAIQFEVIVPSLPGFIFSDKPTKQGFNAIATARIIAKLMYRLNLNNYFVHGTEGYGSDVA 234

  Fly   248 SNIATLYPENVLGYHSNMCNNLSPKSLAKGLVAEFWPSLFVPSGFEDFFFPK--------SNEMR 304
            :.:::|||..:.|.|.:     :|               ||...|..|...|        .:|.|
 Worm   235 TLLSSLYPTRIAGLHLS-----NP---------------FVNPTFSTFTLAKYALKAMGQKDEDR 279

  Fly   305 YLME--ESG------------YF----HIQATKPDTIGAALTDNPVGLAAYI------LEKFSTW 345
            ...|  |:|            ||    ....|.....|||..::|.|.|.||      |..|...
 Worm   280 ENQENRETGKDNRDQMTDLADYFKQDKFAYPTNSQAFGAAFLNSPSGTAKYIESRWKQLSTFFAE 344

  Fly   346 TNPSYRSLPDGGLTKRYKMDALLDNLMIYYLTNSITTSQRL------YAEQYAQAQRDLHLDRVP 404
            ||          |.:.:.||.:...:.:|:||:::.::..:      :...:..:|     .|:|
 Worm   345 TN----------LNELFTMDEIATEIYLYWLTDTLPSALTILDSSFNFESVWLSSQ-----VRIP 394

  Fly   405 TRV------PTGCARFKSDIMQFLDVQLKDKYTNLVHSTYHKKGGHFAALEVPKVLYKDFIDFVE 463
            |.|      |..|::   ||       |:|:|.||...:...|||.|..|:....:.:|...|||
 Worm   395 TAVSYSKQTPWRCSK---DI-------LEDRYLNLTRISELPKGGMFHHLQDGHKIAEDIFSFVE 449

  Fly   464  463
             Worm   450  449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jheh1	NP_611385.1	EHN	64..168	CDD:283978	28/112 (25%)
		MhpC	159..465	CDD:223669	91/355 (26%)
		Abhydrolase_5	159..>255	CDD:289465	32/101 (32%)
C45B11.6	NP_001122878.1	EHN	53..149	CDD:283978	28/114 (25%)
		Abhydrolase	120..>199	CDD:304388	25/79 (32%)
		Abhydrolase_1	140..378	CDD:278959	68/267 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D260574at33208
OrthoFinder	1	1.000	-	-		FOG0002081
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21661
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2361
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.910