Protein Alignment Jheh1 and Ephx1

DIOPT Version :10

• Sequence 1: NP_611385.1
• Gene: Jheh1 / 251984
• FlyBaseID: FBgn0010053
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_034275.1
• Gene: Ephx1 / 13849
• MGIID: 95405
• Length: 455
• Species: Mus musculus
• Alignment Length: 472
• Identity: 195/472 - (41%)
• Similarity: 277/472 - (58%)
• Gaps: 34/472 - (7%)

  Fly     8 LVLILA-IAGGLVYRNVTQLWADLPAPKLDPQE-------WWGDEAQPKDYEAYLKNNSEVIGNR 64
            |.|||| :.|.::|..|::          |.:|       |||..::|.     .|.:..:...:
Mouse     3 LELILASVLGFVIYWFVSR----------DKEETLPLEDGWWGPGSKPS-----AKEDESIRPFK 52

  Fly    65 LSYPDKTIADLKERLNRTLRLTPPLEGVAFEYGFNTNYLKEVVEYWRDDYLPRWREREVFLWQFN 129
            :...|:.|.||.:|::| .|.:|||||..|.||||::|||:||.:||:::  .||::...|.|:.
Mouse    53 VETSDEEIKDLHQRIDR-FRASPPLEGSRFHYGFNSSYLKKVVSFWRNEF--DWRKQVEILNQYP 114

  Fly   130 HFTTDIQGLRTHFLHLMVYDDNKVGKKHYPVLLLHGWPGSVREFYDFIHLLHQTNLDN-NNKYIF 193
            ||.|.|:||..||:|:.. .....|:...|:|::||||||..|||..|.||....... :::::|
Mouse   115 HFKTKIEGLDIHFIHVKP-PQLPSGRTPKPLLMVHGWPGSFYEFYKIIPLLTDPKTHGLSDEHVF 178

  Fly   194 NVVVPSLPGYGWSQGTSRKGLGPAQVAVMMRNLMLRLGYNKFFIQGGDWGSIIGSNIATLYPENV 258
            .|:.||:||||:|:.:|:|||.....|.:...||.|||:.||:||||||||:|.:|||.:.|.:|
Mouse   179 EVICPSIPGYGFSEASSKKGLNSVATARIFYKLMSRLGFQKFYIQGGDWGSLICTNIAQMVPNHV 243

  Fly   259 LGYHSNM---CNNLSPKSLAKGLVAEFWPSLFVPSGFEDFFFPKSNEMRY-LMEESGYFHIQATK 319
            .|.|.||   ..|:  .||...|...|...|.......:..:|...::.| :|.||||.||||||
Mouse   244 KGLHLNMSFISRNI--YSLTPLLGQRFGRFLGYTEKDLELLYPFKEKVFYNIMRESGYLHIQATK 306

  Fly   320 PDTIGAALTDNPVGLAAYILEKFSTWTNPSYRSLPDGGLTKRYKMDALLDNLMIYYLTNSITTSQ 384
            |||:|.||.|:||||||||||||||||...||.|.||||.:::.::.||.|:|||:.|.:|.:||
Mouse   307 PDTVGCALNDSPVGLAAYILEKFSTWTKSEYRELEDGGLERKFSLEDLLTNIMIYWTTGTIVSSQ 371

  Fly   385 RLYAEQYAQAQRDLHLDRVPTRVPTGCARFKSDIMQFLDVQLKDKYTNLVHSTYHKKGGHFAALE 449
            |.|.|...|.......:.:...||||.:.|.|:|:...:..:|.||..|:..:|.::||||||.|
Mouse   372 RFYKENLGQGVMVHRHEGMKVFVPTGYSAFPSEILHAPEKWVKVKYPKLISYSYMERGGHFAAFE 436

  Fly   450 VPKVLYKDFIDFVETVE 466
            .||:|.:|...||...|
Mouse   437 EPKLLAQDIRKFVSLAE 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jheh1	NP_611385.1	EHN	64..173	CDD:461913	46/108 (43%)
		MenH	129..>260	CDD:440361	59/131 (45%)
Ephx1	NP_034275.1	EHN	48..157	CDD:461913	46/112 (41%)
		Abhydrolase_1	142..349	CDD:395444	102/208 (49%)