Protein Alignment Jheh1 and ephx1

DIOPT Version :10

• Sequence 1: NP_611385.1
• Gene: Jheh1 / 251984
• FlyBaseID: FBgn0010053
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001121449.1
• Gene: ephx1 / 100158543
• XenbaseID: XB-GENE-995306
• Length: 457
• Species: Xenopus tropicalis
• Alignment Length: 482
• Identity: 187/482 - (38%)
• Similarity: 273/482 - (56%)
• Gaps: 50/482 - (10%)

  Fly     8 LVLILAIAGGLVYRNVTQLWADLPAPKLDPQE----WWGDEAQPKDYEAYLKNNSEVIGNRLSYP 68
            |:|.||: |.|:|..:.:       .|.:..|    |||...:|.:     :.:.|:...::...
 Frog     5 LLLTLAV-GALLYHFIFK-------KKKETLEMGDGWWGPGVRPDN-----EGDEEIHPFKIETT 56

  Fly    69 DKTIADLKERLNRTLRLTPPLEGVAFEYGFNTNYLKEVVEYWRDDYLPRWREREVFLWQFNHFTT 133
            ::.:.||.:|::.| |.:.||||..|.||||:..|::||.|||:.:  .||::...|.:|.||.|
 Frog    57 EEELKDLFDRIDHT-RYSEPLEGSRFNYGFNSTPLRKVVAYWRNTF--NWRKQLDILNKFPHFKT 118

  Fly   134 DIQGLRTHFLHLMVYDDNKV-----GKKHYPVLLLHGWPGSVREFYDFIHLLHQT---NLDNNNK 190
            .|:||..||:|:      |.     |:...|::::||||||..|||..|..|...   .||  .:
 Frog   119 KIEGLDIHFIHV------KPPHLPGGRTAIPIIMVHGWPGSFYEFYKIIPFLTDPGSHGLD--TQ 175

  Fly   191 YIFNVVVPSLPGYGWSQGTSRKGLGPAQVAVMMRNLMLRLGYNKFFIQGGDWGSIIGSNIATLYP 255
            |||.|:.||:|||.:|:.:.::|.....||.:...||.|||:.:|:.|||||||:|.:|:|.:.|
 Frog   176 YIFEVICPSIPGYSFSEASHKQGCESVAVARIFYKLMRRLGFREFYAQGGDWGSLICTNLAQIAP 240

  Fly   256 ENVLGYHSNMCNNLSPK--SLAKGLVAEFWPSLFVPSGFEDF-------FFPKSNEMRYLMEESG 311
            ..|.|.|.||......|  .:...::.:.:|.||   |..|.       ||.|  .:.::::|||
 Frog   241 NQVKGLHINMAAAFPTKLPQILSVVLGQRFPGLF---GLHDEDVRRIFPFFKK--VVSHVIKESG 300

  Fly   312 YFHIQATKPDTIGAALTDNPVGLAAYILEKFSTWTNPSYRSLPDGGLTKRYKMDALLDNLMIYYL 376
            |.|:|||||||.|..|.::||||||||||||||||:|.:|...||||.:::.:|.||.|:|||:|
 Frog   301 YMHLQATKPDTAGCGLNNSPVGLAAYILEKFSTWTDPDFRDHEDGGLERKFSLDDLLTNIMIYWL 365

  Fly   377 TNSITTSQRLYAEQYAQAQRDLHLDRVPTRVPTGCARFKSDIMQFLDVQLKDKYTNLVHSTYHKK 441
            :.||.:|.|.|.|...:.......|||...||||.|.|.::::.......|.||.|::...|..:
 Frog   366 SGSIVSSMRFYKEVVGKGFGTAKHDRVQVTVPTGVASFPNELVHCPPFWAKQKYVNIISFNYMPR 430

  Fly   442 GGHFAALEVPKVLYKDFIDFVETVERK 468
            ||||||.|.|::|.||...||..||:|
 Frog   431 GGHFAAFEEPELLAKDVQQFVGKVEQK 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jheh1	NP_611385.1	EHN	64..173	CDD:461913	42/113 (37%)
		MenH	129..>260	CDD:440361	56/138 (41%)
ephx1	NP_001121449.1	EHN	48..157	CDD:461913	42/117 (36%)
		alpha/beta hydrolases	143..364	CDD:473884	100/227 (44%)