DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GlcAT-I and B3gat3

DIOPT Version :9

Sequence 1:	NP_726910.1	Gene:	GlcAT-I / 251900	FlyBaseID:	FBgn0066114	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_001121656.1	Gene:	B3gat3 / 293722	RGDID:	1311968	Length:	335	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	138/270 - (51%)
Similarity:	172/270 - (63%)	Gaps:	16/270 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 DTLPTIYAVTPTYPRPAQKAELTRLSHLFMLLPHLHWIIVEDTNATTPLVRNLLDRAGLEKRSTL 111
            :.|||||.:||||.|..|||||.|||....|:|.|||::|||..:.||||..||..:||  ..|.
  Rat    72 EALPTIYVITPTYARLVQKAELVRLSQTLSLVPRLHWLLVEDAESPTPLVSGLLAASGL--LFTH 134

  Fly   112 LNIKTPSEFKLKGKDPNWIKPRGVEQRNLALAWLRNH---VDVDRHS-------IVFFMDDDNSY 166
            |.:.||...:|:..:|.|::||||||||.||.|||..   |..::.|       :|:|.||||:|
  Rat   135 LAVLTPKAQRLREGEPGWVRPRGVEQRNKALDWLRGKGGAVGGEKDSPPPGTQGVVYFADDDNTY 199

  Fly   167 STELFAEMSKIERGRVGVWPVGLVGGLMVERPLLTEDGTKVTGFNAAWRPERPFPIDMAAFAISM 231
            |.|||.|| :..|| |.||||||||||..|.|.: :|| :|.||:.||.|.||||:|||.||:|:
  Rat   200 SRELFKEM-RWTRG-VSVWPVGLVGGLRFEGPRV-QDG-RVVGFHTAWEPNRPFPLDMAGFAVSL 260

  Fly   232 DLFIRNPQATFSYEVQRGYQESEILRHLTTRDQLQPLANRCTDVLVWHTRTEKTKLAAEEALLKK 296
            .|.:..|.|.|.....||:.||.:|.||.....|:|.|..||.||||||||||.|:..||.|.::
  Rat   261 PLLLAKPNAQFDATAPRGHLESSLLSHLVDPKDLEPRAANCTQVLVWHTRTEKPKMKQEEQLQRQ 325

  Fly   297 GQRSDGGMEV 306
            ||.||..:||
  Rat   326 GQGSDPAIEV 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GlcAT-I	NP_726910.1	GlcAT-I	50..284	CDD:132995	125/243 (51%)
B3gat3	NP_001121656.1	GlcAT-I	75..313	CDD:132995	125/243 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352911
Domainoid	1	1.000	200	1.000	Domainoid score	I2944
eggNOG	1	0.900	-	-		E1_KOG1476
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56554
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3135
OMA	1	1.010	-	-		QHG52067
OrthoDB	1	1.010	-	-		D385244at33208
OrthoFinder	1	1.000	-	-		FOG0000504
OrthoInspector	1	1.000	-	-		otm46068
orthoMCL	1	0.900	-	-		OOG6_101385
Panther	1	1.100	-	-	LDO	PTHR10896
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X314
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770