DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GlcAT-I and B3GAT1

DIOPT Version :9

Sequence 1:	NP_726910.1	Gene:	GlcAT-I / 251900	FlyBaseID:	FBgn0066114	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_001354902.1	Gene:	B3GAT1 / 27087	HGNCID:	921	Length:	347	Species:	Homo sapiens

Alignment Length:	346	Identity:	144/346 - (41%)
Similarity:	190/346 - (54%)	Gaps:	60/346 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PRQVLILIIVFLVV----------------LMMVHRN-----GKRTCQGP-------------EY 38
            |::..||.||.:|:                |:.||::     .:.|..|.             |.
Human    15 PKRRDILAIVLIVLPWTLLITVWHQSTLAPLLAVHKDEGSDPRRETPPGADPREYCTSDRDIVEV 79

  Fly    39 LQAMFVQ------GDTLPTIYAVTPTYPRPAQKAELTRLSHLFMLLPHLHWIIVEDTNATTPLVR 97
            ::..:|.      .||||||:.|||||.||.|||||||:::..:.:|:|||::|||....|||..
Human    80 VRTEYVYTRPPPWSDTLPTIHVVTPTYSRPVQKAELTRMANTLLHVPNLHWLVVEDAPRRTPLTA 144

  Fly    98 NLLDRAGLEKRSTLLNIKTPSEFKLKG--KDPNWIKPRGVEQRNLALAWLRNHVDVDRHS----I 156
            .||...||  ..|.|:::||..:||:|  :||.  .|||..||||||.|||.  ...|:|    :
Human   145 RLLRDTGL--NYTHLHVETPRNYKLRGDARDPR--IPRGTMQRNLALRWLRE--TFPRNSSQPGV 203

  Fly   157 VFFMDDDNSYSTELFAEMSKIERGRVGVWPVGLVGGLMVERPLLTEDGTKVTGFNAAWRPERPFP 221
            |:|.||||:||.|||.||....  ||.||||..||||..|.|.:...| ||.|:...:.|.|||.
Human   204 VYFADDDNTYSLELFEEMRSTR--RVSVWPVAFVGGLRYEAPRVNGAG-KVVGWKTVFDPHRPFA 265

  Fly   222 IDMAAFAISMDLFIRNPQATFSYE-VQRGYQESEILRHLTTRDQLQPLANRCTDVLVWHTRTEKT 285
            ||||.||:::.|.::..||.|... |:.|||||.:||.|.|.:.|:|.|..||.:|||||||||.
Human   266 IDMAGFAVNLRLILQRSQAYFKLRGVKGGYQESSLLRELVTLNDLEPKAANCTKILVWHTRTEKP 330

  Fly   286 KLAAEEALLKKGQRSDGGMEV 306
            .|..|.   ||| .:|..:|:
Human   331 VLVNEG---KKG-FTDPSVEI 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GlcAT-I	NP_726910.1	GlcAT-I	50..284	CDD:132995	119/240 (50%)
B3GAT1	NP_001354902.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	195	1.000	Domainoid score	I3154
eggNOG	1	0.900	-	-		E1_KOG1476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52067
OrthoDB	1	1.010	-	-		D385244at33208
OrthoFinder	1	1.000	-	-		FOG0000504
OrthoInspector	1	1.000	-	-		otm41931
orthoMCL	1	0.900	-	-		OOG6_101385
Panther	1	1.100	-	-	O	PTHR10896
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X314
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.790