Protein Alignment GlcAT-I and B3GAT1

DIOPT Version :10

• Sequence 1: NP_726910.1
• Gene: GlcAT-I / 251900
• FlyBaseID: FBgn0066114
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_001354902.1
• Gene: B3GAT1 / 27087
• HGNCID: 921
• Length: 347
• Species: Homo sapiens
• Alignment Length: 346
• Identity: 144/346 - (41%)
• Similarity: 190/346 - (54%)
• Gaps: 60/346 - (17%)

  Fly     8 PRQVLILIIVFLVV----------------LMMVHRN-----GKRTCQGP-------------EY 38
            |::..||.||.:|:                |:.||::     .:.|..|.             |.
Human    15 PKRRDILAIVLIVLPWTLLITVWHQSTLAPLLAVHKDEGSDPRRETPPGADPREYCTSDRDIVEV 79

  Fly    39 LQAMFVQ------GDTLPTIYAVTPTYPRPAQKAELTRLSHLFMLLPHLHWIIVEDTNATTPLVR 97
            ::..:|.      .||||||:.|||||.||.|||||||:::..:.:|:|||::|||....|||..
Human    80 VRTEYVYTRPPPWSDTLPTIHVVTPTYSRPVQKAELTRMANTLLHVPNLHWLVVEDAPRRTPLTA 144

  Fly    98 NLLDRAGLEKRSTLLNIKTPSEFKLKG--KDPNWIKPRGVEQRNLALAWLRNHVDVDRHS----I 156
            .||...||  ..|.|:::||..:||:|  :||.  .|||..||||||.|||.  ...|:|    :
Human   145 RLLRDTGL--NYTHLHVETPRNYKLRGDARDPR--IPRGTMQRNLALRWLRE--TFPRNSSQPGV 203

  Fly   157 VFFMDDDNSYSTELFAEMSKIERGRVGVWPVGLVGGLMVERPLLTEDGTKVTGFNAAWRPERPFP 221
            |:|.||||:||.|||.||....  ||.||||..||||..|.|.:...| ||.|:...:.|.|||.
Human   204 VYFADDDNTYSLELFEEMRSTR--RVSVWPVAFVGGLRYEAPRVNGAG-KVVGWKTVFDPHRPFA 265

  Fly   222 IDMAAFAISMDLFIRNPQATFSYE-VQRGYQESEILRHLTTRDQLQPLANRCTDVLVWHTRTEKT 285
            ||||.||:::.|.::..||.|... |:.|||||.:||.|.|.:.|:|.|..||.:|||||||||.
Human   266 IDMAGFAVNLRLILQRSQAYFKLRGVKGGYQESSLLRELVTLNDLEPKAANCTKILVWHTRTEKP 330

  Fly   286 KLAAEEALLKKGQRSDGGMEV 306
            .|..|.   ||| .:|..:|:
Human   331 VLVNEG---KKG-FTDPSVEI 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlcAT-I	NP_726910.1	GlcAT-I	50..284	CDD:132995	119/240 (50%)
B3GAT1	NP_001354902.1	Glyco_transf_43	118..328	CDD:460898	101/218 (46%)