DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GlcAT-I and sqv-8

DIOPT Version :9

Sequence 1:	NP_726910.1	Gene:	GlcAT-I / 251900	FlyBaseID:	FBgn0066114	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_496076.1	Gene:	sqv-8 / 174517	WormBaseID:	WBGene00005026	Length:	356	Species:	Caenorhabditis elegans

Alignment Length:	279	Identity:	133/279 - (47%)
Similarity:	188/279 - (67%)	Gaps:	11/279 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 MVHRNGK---RTCQGPEYLQAMFVQGDTLPTIYAVTPTYPRPAQKAELTRLSHLFMLLPHLHWII 85
            :|..|||   ...|..::|..:.....:.|.||.:|||:.|.||:|:|||||:....:|:||||:
Worm    68 LVRLNGKVEEIDTQIRDHLSLLPRVNRSTPFIYFITPTHFRAAQRADLTRLSYTLSHVPNLHWIV 132

  Fly    86 VEDTNATTPLVRNLLDRAGLEKRSTLLNIKTPSEFKLKGKDPNWIKPRGVEQRNLALAWLRNHVD 150
            |||::..||.:..:|.|:.:.  :|.||.:|||:.|::..||||..||||||||.||.|::|.:.
Worm   133 VEDSDELTPSIAGILKRSKIP--NTHLNARTPSDQKMRYDDPNWTLPRGVEQRNRALLWIQNQLS 195

  Fly   151 VDRHSIVFFMDDDNSYSTELFAEMSKIERGRVGVWPVGLVGGLMVERPLLTEDGTKVTGFNAAWR 215
            ..:..:|:|.||||:|..::|.||.|::  ..||||||:|||:.||.|:|.::|: ::.|||.|:
Worm   196 GVKEGVVYFGDDDNTYDLKIFGEMRKVK--NAGVWPVGIVGGMFVETPILEKNGS-ISHFNAVWK 257

  Fly   216 PERPFPIDMAAFAISMDLFIRNPQATFSYEVQRGYQESEILRHL-TTRDQLQPLANRCTDVLVWH 279
            |||||||||||||:::.|.:.|..|.||::|.||||||..|.:| ..|..::|||..||.|.|||
Worm   258 PERPFPIDMAAFAVNISLVLSNANALFSFDVPRGYQESTFLENLGIHRYNMEPLAEMCTKVYVWH 322

  Fly   280 TRTEKTKLAAE--EALLKK 296
            |||||.||:.|  :.|.||
Worm   323 TRTEKPKLSKESIDRLTKK 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GlcAT-I	NP_726910.1	GlcAT-I	50..284	CDD:132995	119/234 (51%)
sqv-8	NP_496076.1	DivIC	15..86	CDD:299713	5/17 (29%)
sqv-8	NP_496076.1	GlcAT-I	97..327	CDD:132995	119/234 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	223	1.000	Domainoid score	I1464
eggNOG	1	0.900	-	-		E1_KOG1476
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56554
Inparanoid	1	1.050	256	1.000	Inparanoid score	I1948
Isobase	1	0.950	-	0	Normalized mean entropy	S3762
OMA	1	1.010	-	-		QHG52067
OrthoDB	1	1.010	-	-		D385244at33208
OrthoFinder	1	1.000	-	-		FOG0000504
OrthoInspector	1	1.000	-	-		oto19564
orthoMCL	1	0.900	-	-		OOG6_101385
Panther	1	1.100	-	-	LDO	PTHR10896
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2815
SonicParanoid	1	1.000	-	-		X314
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.820