DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GlcAT-I and B3GAT2

DIOPT Version :9

Sequence 1:	NP_726910.1	Gene:	GlcAT-I / 251900	FlyBaseID:	FBgn0066114	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_542780.1	Gene:	B3GAT2 / 135152	HGNCID:	922	Length:	323	Species:	Homo sapiens

Alignment Length:	272	Identity:	136/272 - (50%)
Similarity:	164/272 - (60%)	Gaps:	34/272 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 RNGKRTCQGPEYLQAMFVQGDTLPTIYAVTPTYPRPAQKAELTRLSHLFMLLPHLHWIIVEDTNA 91
            ||..|....||         ..||||||:||||.||.||||||||::.|..:..||||:|||..|
Human    66 RNQSRPQPQPE---------PQLPTIYAITPTYSRPVQKAELTRLANTFRQVAQLHWILVEDAAA 121

  Fly    92 TTPLVRNLLDRAGLEKRSTLLNIKTPSEFKLKGKDPNWIKPRGVEQRNLALAWLRNHVDVDRH-- 154
            .:.||...|.||||.  ||.|::.||..:|..|      .||..||||..|||||     .||
Human   122 RSELVSRFLARAGLP--STHLHVPTPRRYKRPG------LPRATEQRNAGLAWLR-----QRHQH 173

  Fly   155 -----SIVFFMDDDNSYSTELFAEMSKIERGRVGVWPVGLVGGLMVERPLLTEDGTKVTGFNAAW 214
                 .::||.||||:||.|||.||....  :|.|||||||||...||||: |:| ||.|:...|
Human   174 QRAQPGVLFFADDDNTYSLELFQEMRTTR--KVSVWPVGLVGGRRYERPLV-ENG-KVVGWYTGW 234

  Fly   215 RPERPFPIDMAAFAISMDLFIRNPQATFSYE-VQRGYQESEILRHLTTRDQLQPLANRCTDVLVW 278
            |.:|||.||||.||:|:.:.:.||:|.|... .|.|.|||:.|:.:||.::|:|.||.||.||||
Human   235 RADRPFAIDMAGFAVSLQVILSNPKAVFKRRGSQPGMQESDFLKQITTVEELEPKANNCTKVLVW 299

  Fly   279 HTRTEKTKLAAE 290
            ||||||..||.|
Human   300 HTRTEKVNLANE 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GlcAT-I	NP_726910.1	GlcAT-I	50..284	CDD:132995	125/241 (52%)
B3GAT2	NP_542780.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	51..80		5/22 (23%)
		GlcAT-I	81..305	CDD:132995	124/240 (52%)
		Interaction with galactose moiety of substrate glycoprotein. /evidence=ECO:0000250	234..243		5/8 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52067
OrthoDB	1	1.010	-	-		D385244at33208
OrthoFinder	1	1.000	-	-		FOG0000504
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101385
Panther	1	1.100	-	-	O	PTHR10896
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X314
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.790